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32 Cards in this Set
- Front
- Back
You should consider what three main factors when thinking of how blood pressure is regulated?
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Cardiac Output, Peripheral Resistance, Blood Volume
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In homeostatic management, when one factor decreases, typically, feedback mechanisms elecate the other two parameters to get blood pressure back up to that "magic number" programmed for that activity level -- even if the programmed number is too high. This presents problems in the management of what? Why?
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Hypertension; as soon as you decrease one factor with drugs, the others go up, elevating blood pressure again.
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Pulse wave and blood pressure decrease as you get further from the heart, T/F
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T
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__________ __________ is the most significant type of resistance and is the resistance that the blood encounters due to it's friction against the walls of the vessels.
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Peripheral Resistance
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Peripheral resistance is influenced by what 3 factors?
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Blood viscosity, Vessel length, Vessel Radius
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Blood viscosity is mostly due to what two things?
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Plasma proteins, erythrocytes
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What is the most abundant plasma protein? Erythrocytes are the most numerous what?
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Albumin, Formed element
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Blood with fewer solutes/cells flows more rapidly than blood with more solutes cells. T/F
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T
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Blood viscosity is likely to change. T/F
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F
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In regards to vessel length, the longer the tube, the greater the?
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Resistance to fluid moving through it
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Vessel length does not change from moment to moment. It will change however, with with large ______ ____ and _____ and can, in that respect, influence ______ ______.
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Weight gains and losses; blood pressure
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Often people who are hypertensive and obese are advised to do what? Why?
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Lose weight to reduce vessel length
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That is the most important (and rapidly variable) factor in determining resistance?
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Vessel radius
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In regards to vessel radius, based on the activity of the _______ (mostly sympathetic) nervous system, _________ can change nearly instantly. Numerous hormones and other agents can also produce _______/________. This does, therefore, change from moment to moment as a normal part of homeostatic regulation that aids in delivering blood to rapidly metabolizing tissues by?
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In regards to vessel radius, based on the activity of the AUTONOMIC (mostly sympathetic) nervous system, VESSEL DIAMETER can change nearly instantly. Numerous hormones and other agents can also produce VASOCONSTRICTION/DIALATION. This does, therefore, change from moment to moment as a normal part of homeostatic regulation that aids in delivering blood to rapidly metabolizing tissues by SHUNTING BLOOD FLOW FROM LESS ACTIVE AREAS.
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A tiny arteriole can constrict down to ______ or less of it's original diameter (remember, the ______ is to the fourth power!)
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one third; radius
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What controls blood flow in a given area from moment to moment based on local chemical conditions?
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Autoregulation
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Autoregulation is an example of what kind of control?
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Local control
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If autoregulation fails, what happens? This is an example of what kind of control?
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The nervous system (specifically the sympathetic branch of the autonomic n.s) becomes involved and rapidly acts in an attempt to correct homeostasis; Neural control
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Vasomotor centers are located near the ______ _____ in the _____ _____. Sometimes these centers are collectively referred to as the ______ ______.
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cardiac centers; medulla oblongata; cardiovascular centers
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Most blood vessels _______ with sympathetic stimulation. Blood vessels supplying skeletal muscle _____ under sympathetic stimulation. Why?
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constrict; dialate; So you can fight or flight.
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The vasomotor centers constantly fire at a _______ rate, maintaining "______", (a moderate degree of vasoconstriction) and keeping the vascular compartment as a whole, matched to our normal ______ _____.
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moderate, "vascular tone", blood volume
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When the baroreceptors are stretched and blood pressure is too high, feedback mechanisms cause ______ to drop. (____________ center is _______ and ________ center is _______.)
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CO; CARDIOACCELERATORY CENTER is INHIBITED and CARDIOINHIBITORY CENTER is STIMULATED.
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When the baroreceptors are stretched and blood pressure is too _____, ________ _______ cause CO to drop.
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high; feedback mechanisms
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When the baroreceptors are stretched and blood pressure is too high, feedback mechanisms cause CO to drop. (Cardioacceleratory center is inhibited and Cardioinhibitory center is stimulated). The vasomotor centers also fire less, thus?
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Lowering blood pressure
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In regards to baroreceptors, the opposite feedback occurs when there is too little ______ and the _______ is too low.
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stretch, blood pressure
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In regards to baroreceptors, the ______ ______occurs when there is too little stretch and the blood pressure is too low.
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opposite feedback
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In regards to baroreceptors, the opposite feedback occurs when there is too little stretch and the blood pressure is too low. These feedback mechanisms function to perform what? Give an example.
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Short term corrections, such as when we change posture.
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These respond to blood chemistry changes by adjusting respiration, CO, and vasomotion. Give two examples.
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Chemoreflexes; Aortic bodies and Carotid bodies.
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Chemoreflexes respond to what three things? Where are they located? If any of these occur, feedback response is to do what? The most sensitive chemoreceptors are?
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Low pH, High carbon dioxide levels, Low oxygen levels; In the major arteries and medulla oblongata; Any one or combination of these conditions will activate feedback response is to increase blood pressure/CO. Most sensitive to decrease in pH and increase in carbon dioxide.
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Specific reflex that protects the brain during sudden drops in perfusion rate there through initiation of widespread vasoconstriction and increases in HR and SV.
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Medullary Ischemic Reflex.
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Medullary Ischemic Reflex: Specific reflex that protects the brain during what? What does it do to protect it?
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Sudden drops in perfusion rate there through initiation of widespread vasoconstriction and increases in HR and SV.
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Homeostatic regulation of blood volume usually involves the ______ ______ and is a more ______ _____ means of control
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endocrine system; long term
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