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14 Cards in this Set

  • Front
  • Back
Name the two causes of myocardial ischemia.
1. Impairment of coronary flow.
2. Elevated myocardial oxygen demand
Explain what happens to ATP during cardiac ischemia.
oxidative phosphorylation can't proceed because of a lack of oxygen so ATP production and myocardial contractility drops
What are free radicals?
particles released after a cardiac ischemia that can damage myocardial tissue
What is myocardial infarction?
myocardial cell death due to prolonged cardiac ischemia
Name 4 diagnosis tools of myocardial infarction.
1. Clinical signs and history
2. ECG analysis
3. Protein markers
4. Imaging
Name the 3 hemodynamic consequences of a heart attack.
1. Cardiac output decreases.
2. Venous pressure and right atrial pressure increase.
3. Arterial pressure drops
Name the 5 sympathetic responses to a heart attack.
1. Heart rate increases.
2. Healthy muscle beats more forcefully.
3. Vasoconstriction
4. Renin-angiotensin-aldosterone system activation
5. Release of epinephrine
What happens if sympathetic activation isnt enough to correct cardiac ouput?
Decompensation
Describe the effects of decompensation.
Retention of fluid by the kidneys.
What are "rales"
The sounds heard by a doctor when examining edemic lungs?
When does cardiogenic shock occur?
When more than 40% of the myocardium has undergone myocardial infarction.
What happens when the left ventricle fails?
Rise in blood pressure in the pulmonary circuit...which in turn causes pulmonary edema.
What happens when the right ventricle fails?
peripheral edema...rise in venous pressure
Name 3 different types of interventions used to restore the Supply-Demand mismatch after a heart attack.
1. Reduction of Myocardial Oxygen Demand.
2. Increasing Coronary Flow: Reperfusion Strategies.
3. Medication