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51 Cards in this Set
- Front
- Back
Cortical nephrons are the most abundant type of nephron
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true |
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The nephron loop (loop of Henle) is located in the renal cortex
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false, renal medulla |
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Juxtamedullary nephrons extend into the renal medulla
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true |
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The glomerulus and the glomerular capsule are components of the renal corpuscle
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true |
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The renal tubule is located in the renal cortex
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true (both the cortex and medulla) |
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. The proximal convoluted tubule is part of the renal tubul
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true |
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Filtration takes place in the renal cortex
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true
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Most tubular reabsorption takes place in the distal convoluted tubule
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False, proximal convoluted tubules |
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Urine is concentrated in the collecting duct
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true |
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Filtrate contains red blood cells
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False, does not contain |
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Glucose is reabsorbed from the filtrate in the proximal convoluted tubule
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True |
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Vasa recta are permeable to water and NaCl
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True |
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The interstitial fluid of the renal medulla is greater in osmolality than the renal cortex.
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True |
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Urine is formed in the urinary bladder
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False, it is formed in nephrons and stored in the bladder
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Tubular secretion takes substances out of the filtrate
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False, secretion puts substance in, reabsorption takes out
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. Filtrate reaches its lowest concentration at the bottom of the nephron loop
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False, highest at bottom
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Glomerular filtration rate will increase if blood pressure increases
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True |
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Hydrostatic pressure of the glomerular capillaries will increase if resistance in the afferent arteriolesincreases
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False, Resistance will decrease blood flow and decrease hydrostatic pressure
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Increasing the resistance of afferent arterioles will increase blood flow to the glomerulus
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False |
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Efferent arterioles are smaller in diameter than afferent arterioles
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True |
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Filtration and reabsorption take place in glomerular capillaries
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False , filtration only
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In the absence of Antidiuretic hormone (ADH) urine is dilute
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True |
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Urine is 95% water |
True |
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The ureter carries urine from the bladder to the body exterior
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False, ureter = renal pelvis to bladderUrethra = bladder to exterior
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Water is actively pumped out of the collecting duct by aquaporins
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False, osmosis is passive
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The calyces and renal pelvis collect urine from the collecting ducts in the renal pyramids
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True |
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The male urethra is part of the reproductive system
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True |
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The internal urethral sphincter is voluntarily controlled
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False, internal = involuntary, external = voluntary
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Urine is yellow in color due to the presence of a chemical called Urobillin (aka urochrome)
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True |
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Urine is yellow in color due to the presence of a chemical called Urobillin (aka urochrome)
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Descending
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Permeable to water
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Descending
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Actively pumps NaCl out of the filtrate
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Ascending
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Filtrate is being concentrated
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Descending
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Filtrate is being diluted
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Ascending
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Solute concentration of the filtrate is high
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Descending
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Impermeable to water
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Ascending
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Located in ascending limb
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Macula Densa
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Contain mechanoreceptors which respond to blood pressure
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Granular
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Release renin
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Granular
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Contain chemoreceptors which respond to NaCl in filtrate
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Macula Densa
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Located in arteriolar wall
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Granular
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Vasoconstrict afferent arterioles in the kidney
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Macula Densa
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Vasoconstrict systemic blood vessels
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Granular
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Part of the intrinsic mechanisms used by the kidneys to autoregulate the GFR
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Macula Densa
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Part of the extrinsic mechanisms used to indirectly modify the GFR
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Granular
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1. The glomerular filtration rate (GFR) in a patient is much too fast. Will this result in low or high NaCl inthe filtrate passing through the ascending limb of the nephron loop? How will Macula Densa cellsrespond, as part of the intrinsic to help lower the GFR?
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Since the filtration rate is so fast, the filtrate will advance through the renal tubules too quickly forreabsorption of salt. So, there will be a high level of NaCl in the filtrate passing in to the ascendinglimb of the nephron loop. The Macula Densa cells contain chemoreceptors which will detect thepresence of high NaCl, release vasoconstrictor chemicals which will: decrease the diameter of theafferent arterioles, increase arteriole resistance, decreasing blood flow, decrease hydrostaticpressure in the glomerular capillaries and ultimately decrease the glomerular filtration rate (GFR).
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Aside from depressing the nervous system and coordination, why is it a bad idea to drink alcoholbefore exercising – particularly in hot and dry conditions?
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Alcohol will block the production and secretion of anti-diuretic hormone (ADH) from the posteriorpituitary. ADH normally inserts aquaporin channels into the plasma membrane of tubule cellslining the collecting duct, allowing for the reabsorption of water (by using the medullary osmoticgradient!). If ADH is blocked, then water reabsorption is blocked. As a result, dilute urine will beproduced in large volume. This will only make dehydration more of a concern during exercise inhot, dry conditions
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A patient begins taking Lasix and experiences episodes of fainting and orthostatic hypotension. Whatis happening?
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Lasix is a loop diuretic drug used to treat hypertension (high blood pressure). It works by blockingNaCl pumps in the ascending limb of the nephron loop. This will prevent the juxtamedullarynephrons from creating an osmotic gradient in the interstitial fluid of the renal medulla. Withoutthis gradient, reabsorption of water will not take place in the collecting duct (even if ADH insertsaquaporin channels, there is no gradient for water to follow). This will produce large volumes ofurine. Ridding the bod of excess water can reduce the blood volume and decrease blood pressure.But, if a patient has only border line high blood pressure or is dehydrated, dangerously low bloodpressure may result in fainting and orthostatic hypotension because of reduced blood flow to thebrain.
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Female reproductive events are regulated by cycling levels of hormones over a period of about 28 days.Events taking place in the __________ are described by the ovarian cycle.
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ovaries |
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Events taking place in theuterus are described by the ______________________.
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uterine/menstrual cycle |
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___________ is secreted by the hypothalamus and stimulates the anterior pituitaryto produce and release the gonadotropins _________ and _________
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GnRH, LH, FSH |