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217 Cards in this Set

  • Front
  • Back

Atoms

Smallest units of matter; atoms combine to form molecules.

Cell

Smallest living units in the body; cells contain organelles which are formed from molecules.

Tissues

Many similar cells grouped together to perform a function or series of related functions. There are four main groups of tissues; epithelial, connective, muscular and nervous.

Organ

Several different types of tissues grouped together to perform a function of a series of related functions. A few examples of organs would be the kidney, liver, brain and heart.

Organ Systems

Several organs working together to perform a series of related functions. An example of an organ system is the respiratory system or the cardiovascular system.

Organism

A form of life composed of mutually interdependent parts that maintain various vital processes; - a form of life considered as an entity.

Anatomy

The study of the structures that make up the body and how those structures relate to each other. The Greek translation of the word anatomy means, "to cut up".

Gross Anatomy

The study of body structures that can be seen without a microscope.

Microscopic Anatomy

The study of the tiny structures of the body that can only be seen with a microscope.

Physiology

The study of how the body functions and carries out the activities of life.

Anatomical Position

Standing forward, feet together, palms forward.

Supine

Body lying face up in anatomical position.

Prone

Body lying face down in anatomical position.

Axial

Body, head, chest, abdomen, pelvis.

Appendicular

Limbs extremities, arms and legs

Right

The subject's right side (not the observers)

Left

The subject's left side (not the observers)

Planes of the body

Traverse, sagittal, midsagittal, parasagittal, frontal (Coronal)

Tranverse Plane

(Cross section) Divides the body into inferior and superior sections.

Sagittal Plane

Divides the body into left and right halves

Midsagittal Plane

Divides the body into equal left and right halves

Parasagittal Plane

Divides the body into unequal left and right halves.

Frontal (Coronal) Plane

Divides the body into posterior and anterior portions.

Superior (Cranial)

above, toward the head. The leg is superior to the foot.


Inferior (caudal)

Below; toward the feet. The foot is inferior to the leg.

Anterior (ventral)

Toward the front of the body. The nose is anterior to the ears.

Posterior (dorsal)

Toward the back of the body. The ears are posterior to the nose.

Rostral

Situated toward the oral or nasal region.

Medial

Toward the midline of the body. The heart is medial to the lungs.

Lateral

Away from the midline. The eyes are lateral to the nose.

Proximal

Toward (nearer) the trunk of the body; closer to the point of attachment. The elbow is proximal to the wrist.

Distal

Away (farther) from the trunk of the body; further away from the point of attachment. The wrist is distal to the elbow.

Superficial (external)

Nearer to the surface of the body; toward or on the surface of the body. The skin is superficial to the muscles.

Deep (internal)

Away from the surface of the body; farther from the surface of the body. The muscles are deeper than the skin.

Abdominopelvic Quadrants

Right upper


Left upper


Right Lower


Left lower

Abdominopelvic Regions

Right hypochondriac region


Epigastric region


Left Hypochondriac region


Right lumbar region


Umbilical region


Left lumbar region


Right inguinal (iliac) region


Hypogastric region


Left inguinal (ilian) region

Body Cavities

Dorsal


Cranial cavity


Spinal cavity


Ventral


Thoracic cavity


Pleural cavities


Pericardial cavity


Mediastinum


Abdominopelvic (peritoneal) cavity


Pelvic cavity


Abdominal cavity


Cranial Cavity

Contains the brain

Spinal Cavity

Contains the spinal cord

Pleural cavities

surrounds left and right lungs

Pericardial cavity

Surrounds heart

Mediastinum

Partition area between the lungs.

Pelvic Cavity

Contains urinary bladder, reproductive organs.

Abdominal Cavity

Contains digestive organs and many glands.


Organ Systems

Integumentary System


Skeletal System


Muscular System


Nervous System


Edocrine System


Cardiovascular System


Lymphatic System


Respiratory System


Digestive System


Urinary System


Reproductive System

Integumentary System

Skin, hair, nails and exocrine glands (sweat and sebaceous glands).

Skeletal System

Bones, cartilage, tendons, ligaments

Muscular System

Skeletal muscles, smooth muscles, cardiac muscles.

Nervous System

Central nervous system (brain and spinal cord) and peripheral nervous system.

Endocrine System

Pituitary, thyroid, parathyroid, pineal, adrenal glands, pancreas, ovaries, testes.

Cardiovascular System

Heart, blood vessels, and blood

Lymphatic System

Lymphatic vessels, nodes, spleen and thymus

Respiratory System

Lungs, alveoli, bronchi, trachea, larynx, pharynx, and nasal cavity, diaphragm

Digestive System

Oral cavity, pharynx, esophagus, stomach, small intestine and large intestine, liver, pancreas and gallbladder.

Urinary System

Kidneys, ureters, urinary bladder, urethra.

Reproductive System

Male: testes, prostate gland, Cowper's glands, seminal vesicles, ductus deferens, penis.



Female: ovaries, uterine tubes, uterus, vagina

Types of microscopes

Compound Light Microscope


Stereoscopic or dissecting


Micro-video System


Photographic microscope


Phase-contrast microscope


Scanning electron microscope


Transmission electron microscope

Compound Light microscope

uses a series of lenses and a light source

Stereoscopic (or Dissecting) Microscope

Used to view objects in 3D

Micro-video System

Uses a compound light microscope with a camera attached.

Photographic Microscope

uses a compound light microscope with a camera attached to produce a photmicrograph

Phase-contrast Microscope

Filters out certain light rays to view certain structures better (especially clear objects)

Scanning electron microscope

Shines a beam of electrons across the surface of an object in a vacuum that gives an image of surface and dimensions of an object.

Transmission electron microscope

Uses electrons in a vacuum to view ultra-thinly slice objects that have been treated with heavy metal salts to improve contrast.

Monocular

One ocular lense

Binocular

Two ocular lenses


Nosepiece

Holds and moves objective lenses on microscope

Condenser

A series of lenses that you can move up and down to condense and clarify the light shining through the object.


Cells

The building blocks of life


The study of of cells is cytology


Organelles

"little organs" within the cell carry out the functions of the cell.


Plant cells: usually square


Animal cells: generally round


Plant cells

usually square


contain cellulose, which helps to strengthen and support the cell.


Also contacin chloroplasts where photosynthesis occurs.

Cell (plasma) membrane

surrounds animal cells.


Semi-permeable


Provides form to cell and controls passage of materials into and out of cell.


Forms a thin, protective layer around the cell.


Made up of two phopholipid molecules. One of the end phospholip molecules has a charged polar end (hydrophilic) while the other end has an uncharged nonpolar end (hydrophobic).


Some proteins are loosely bound on the surface and may function as receiptors, channels, carriers, enzymes, anchors or identifiers.


Others are embedded in the phospholipid bilayer.


Nucleaus

control center of the cell


Suspended in cytosol

Cytosol

gel-like fluid where nucleus and other organelles are suspended and materials are diffused.


Cytoplasm

The collective term given to the cytosol and the organelles. Each organelle performs specific functions in the cell.

Nucleolus

Dense area found within nucleus, forms ribosomes.

Mitochondria

"powerhouse" of the cell: produces ATP whic provides energy for cellular metabolism.


(singular: Mitochonrion)

Endoplasmic Reticulum

Membranous flattened channels and canal-like structures found throughout cytosol, provides transport of substances, synthesizes proteins and other products.


Rough Endoplasmic Reticulum

Ribosomes are attached to the surface of the membrane giving the ER a "rough appearance", contains newly synthesized proteins.

Smooth Endoplasmic Reticulum

Contains no ribosomes, lipid and carbohydrate synthesis

Ribosomes

Site of protein synthesis

Golgi Apparatus

Flattened sacs with vacuoles, synthesizes carbohydrates and packages molecules for secretion.

Lysomes

Membranous sacs containing digestive enzymes used to break down damaged cell parts and foreign substances: sometimes called "suicide bags" due to the fact that when lysosomes rupture within the cell, they detroy it.

Peroxisomes

Membranous vesicles containing exzymes that degrade and neutralize toxic compounds; smaller than lysosomes.

Cilia

Short, membranous extensions of the cell which move materials over the cell surface.

Flagella

Long, membranous extensions of the cell which provide means of movement for sperm.

Microtubules

Hollow, slender, cylindrical structures which provide strength and support and assist in movement of cellular structures and material.

Microfilaments

Solid, rodlike structures containing the protein actin which provide structural support and assist cell movement.

Microvilli

Membrane extensions which contain microfilaments; increase surface area.

Centriole

Composed of 9 triplet microtubules, assist in movement of chromosomes during cell division; form basal body of cilia and flagella.

Centrosome

Cytoplasm containing two centrioles at right angles.

Hydro-

water

-philic

loving


-phobic

fearing, hating

Water

Makes up 2/3 total body weight.


Vital to matabolism.


Transports substances and helps lubricate and cushion organs.


Acts as a solvent for viochemical reactions.


Considered universal solvent.


Helps control temperature of body by evaporation through theskin.


H2O > the oxygen atom is negative


the hydrogen atom has a positive charge


because the charges are different - they are considered polar molecules.


A person can live about 3 days without water.

Solvent

a liquid or gas capable of dissolving another substance.

Solute

The substance being dissolved

Solution

mixture of solvent and dissolved solute.


Somatic Cells

All other body cells except sex cells

Mitosis

nuclear division of somatic cells

Meisois

nuclear division of sex cells

Dipolid

normal somatic number of chromosomes (46)

Haploid

Half the dipoid number of chromosomes (23) egg and sperm contain the haploid chromosome number due to meiosis.

Chromosome

coils of DNA

Chromatid

one strand of a double stranded chromosome

Centromere

Cener of a chromosome

Deoxyribonucleic Acid (DNA)

Nucleic acid containing cellular information.


Made up of two linear strands of repeating subunits (nitrogenous bases)


Double helix


Each nucleotide has 3 components: a sugar, photphate group and a nitrogenous base.


The sugar is always a 5-carbon sugar, either ribose in RNA or deoxyribose in DNA.


Made up of 4 kinds of nitrogenous bases:


Adenine (A)


Guanine (G)


Ctyosin (C)


Thymine (T)



All bases bonded together by sugar - phospate linkages.


Adenine and Thymine always bond together adn Cytosine and Guanine always bond together.

Nucleic Acids

large molecules made up of carbon, hydrogen, oxygen, nitrogen and phosphorus.


Responsible for storing and regulating protein synthesis in the nucleus.


Two types: RNA & DNA

RNA

riboninucleic acid


involved in transcriptoin and translation of the genetic code.


Contains a fifth nitrogenous base (uracil) U

Mitosis

The division of somatic (body) cell nuclei.


Results in the replication of the dipoid (normal somatic) choromosome number (all daughter cells contain the same kind and number of chromosomes as the parent cell). In human body cells the dipoloid chromosome number is 46.


The sex cells each contain 23 chromosomes.

4 main types of tissue

Epithelial


Connective


Muscle


Neural

Basement Membrane

The layer of filaments and fibers that attach an epithelium to the underlying connective tissue.

Epithelial Tissue

Covers all the surfaces of the body, including the external surfaces, the inner lining of the digestive, respiratory, circulatory, excretory and reproductive systems, and the dorsal and ventral body cavities.


Types of epithelial tissue

squamous, cuboidal, columnar, transitional & goblet.

Connective tissue

Serves to bind or support the organs and is the most widely distributed tissue in the body.

Types of connective tissues

Loose connective tissue, adipose tissue, dense connective tissue, elastic connective tissue, blood, cartilage & bone.

Muscle Tissue

Characterized by irritability, excitability, elasticity and contractility. Contractile fibrils in the cells enable the tissue to shorten, generating a force, and producing movement.

Intercalated disc

Specialized cell junctions between heart muscle cells that facilitate the passing of an impulse from one heart cell to the next.

Nervous tissue

Serves to coordinate systems in the body.


Types: Neuron (nerve cell)


Neuroglia (supporting cells)

Types of membrane permeability

impermeable - nothing can cross


freely permeable - anything can cross


semipermeable - some things can cross but some things can't.

Factors that determine how a substance will get in and out of a cell

1. Molecular size


2. Electrical Charge


3. Lipid solubility


4. Carrier molecule availability


5. Energy

Simple Diffusion

The process in which molecules spread out randomly from heavily concentrated areas to areas of lesser concentration until they are distributed evenly in a state of equilibrium.


Concentration gradient

The difference in concentration of molecules in a given area. (as a result of diffusion)

Facilitated diffusion

When molecules pass through the cell membrane with assistance from other cellular structures such as large proteins.


Carrier proteins temporarily bind with the molecules to assist them in passing through the cell membrane. the carrier protein changes shape to allow passage through the cell membrane, deposits the molecule and returns to its original shape.

Carrier proteins

proteins that temporarily bind with the molecules to assist them in passing through the cell membrane. Amino acids and glucose use carrier proteins to enter the cell.


The shape changes to allow passage through the cell membrane. After releasing molecule, the protein returns to its original shape.

Osmosis

The diffusion of water molecules through a semipermeable membrane from a region of higher water concentration to a region of lower water concentration until equilibrium is achieved.


Occurs in red blood cells when water concentration outside the cell is in higher than the water conentration inside the cell (or vice versa)

Osmotic Pressure

pressure developed in a solution due to osmosis.

Solute

particles in a solvent

Solvent

Liquid the solute in it

Solution

the mixture of a solute and solvent.

Integumentary System

Consists mainly of skin but also includes hair, nails and skin.


Skin

part of the integumentary system.


largest organ of the body.


Three main sections: Epidermis, dermis, hypodermis

Epidermis

Outer-most layer of epithelial tissue.


Five layers: Stratum Corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum germinativum

Dermis

Thicker layer of connective tissue beneath the epidermis. It contains blood vessels, nerves, etc.

Hypodermis

(Subcutaneous) layer of loose connective tissue beneath the dermis. It is characterized by the presence of adipose tissue.

Skin Color

Controlled by Carotene - orange, yellow pigment and Melanin - dark brown pigment.


The color of the blood reflected through the epidermis also effects skin color.

Melanin

dark brown pigment produced by cells called melanocytes.


Screens out excessive ultraviolet rays, to protect the nucleus and the genetic material of the cell.

How do wounds heal?

A blood clot is formed which stops external bleeding


A scab forms from the dried blood clot


Phagocytic white blood cells remove damaged tissue and harmful microorganisms.


Epidermal cells multiply under the scab


Cells in the dermis called fibroblasts produce collagenous fibers and form a scar.

Dermatology

The medical study of the physiology and pathology of the skin

Rule of Nines

method of estimating extend of skin burns

Dermatitis

Inflammation of the skin

Scab

A blood clot that forms at the surface of a wound to the skin.

Contusion

A bruise causing bleeding in the dermis

Urticaria

hives

Sebaceous

oil glands connected to hair follicles that function to lubricate and protect.

Sebum

oily secretion

Sudoriferous

Sweat glands: two types: apocrine and merocrine

Apocrine

Large sweat glands (arm pits & genital area)

Merocrine or eccrine

small sweat glands (palms, fingers, soles)

Cerumen

ear wax

Pacinian corpuscles

Receptors for deep pressure

Meissner's corpuscles

(Corpuscles of touch)


Sensitive touch receptors.

Macule

A localized change in skin color (freckles)

Wheal

A localized elevation of the overlying epidermis which accumulates fluid in the papillary dermis. Ex. hives

Papule

A solid elevated area containing epidermal and papillary dermal components. Ex. mosquito or other insect bite.

Nodules

Large papules that may extend into the subcutaneous layer. Ex. cyst

Vesicles

A blister.


a papule with a fluid core. A large vesicle may be called a bulla. Ex. second-degree burn.

Pustule

A papule-sized lesion filled with pus. Ex. acne pimple

Erosion

(An ulcer) may occur following the rupture of a vesicle or pustule. Eroded sites have lost part of all of the normal epidermis. Ex. decubitis ulcer

Crust

An accumulation of dried sebum, blood, or interstitial fluid over the surface of the epidermis. Ex. seborrheic dermatitis, scabs, impetigo.

Scales

Thin plates of cornified cells which form as a result of abnormal keratinization. Ex. psoriasis

Fissure

A split in the integument that extends through the epidermis and into the dermis. Ex. athletes foot

Major types of open wounds

Abrasion


Incision


Laceration


Puncture


Avulsion

Laceration

jagged, irregular tear in the surface produced by solid impact or by an irregular object.

Avulsion

chunks of tissue are torn away by force

Major Classification of Bones

Long Bones (ex. femur)


Short Bones (ex. carpal)


Flat Bones (ex. skull bones)


Irregular Bones (ex. spinal vertebrae)


Sesamoid Bones (develop inside tendons) (ex. patella)


Sutural Bones (Wormian Bones) found between the skull bones.

Typical Long Bones

Has three general parts:


Epihysis - the ends of the bone (head)


Diaphsis - the long, hollow shaft of the bone


Metaphysis - the flared region where the epiphysis and diaphysis meet.

Compact bone

Is dense and relatively solid


Under microscopic cross section, appears to have a pattern of concentric rings (osteons or Haversian systems)

Spongy Bone

forms an open network of struts and plates (contains red marrow)


Made up of a latticework of thin, bony plates called trabeculae. The spaces between the trabeculae of the spongy bone are filled with red marrow, which produces red blood cells, some white cells and platelets.

Process

surface marking of bone


a projection or bump

Ramus

surface marking of bone


angle of a bone

trochanter

surface marking of bone


very large, rough, rounded projection (present only in femur)

tuberosity

surface marking of bones


large (smaller than trochanter), rough rounded projection

Tubercle

Surface marking of bones


small, rough, rounded projection

Crest

Surface marking of bones


prominent projection or ridge

Line

Surface marking of bones


narrow, low ridge


Spine

Surface marking of bones


Pointed process

Head

surface marking of bones


expanded, rounded surface at end of bone.

Condyle

Surface marking of bones


large, convex projection that usually contacts another bone.

Trochlea

surface marking of bones


grooved surface shaped like a pulley

Facet

Surface marking of bones


small smooth, flat surface

Fossa

Surface marking of bones


Shallow depression or concavity

Foramen

Surface marking of bones


natural opening on a bone surface for nerves and/or blood vessels

Fissure

Surface marking of bones


deep cleft between adjacent parts of bone


Meatus

Surface marking of bones


Canal


Sinus or antrum

Surface marking of bones


hollow space within bone

Axial Bones

Mandible


Maxilla


Frontal


Parietal


Occipital


Hyoid


Temporal


Strenum


Vertebrae


Ribs


Sacrum & Coccyx

Appendicular Skeleton

Clavicle


Scapula


Humerus


Radius


Ulna


Carpals & Metacarpals


Phalanges


Coxal Bone


Femur


Patella


Tibia


Fibula


Tarsals & Metatarsals


Long bone

Has three general parts:


Epiphysis


Diaphysis


Metaphysis

Epiphysis

The ends of the bone


have only a thin layer of compact bone surrounding a larger network of spongy bone.

Diaphysis

The long, hollow shaft of the bone

Metaphysis

The flared region where the epiphysis and diaphysis meet.


The growing portion of the bone.


Consists of spongy bone covered with compact bone and an epiphyseal (growth) plate.

Medullary cavity

Cavity within diaphysis that contains yellow marrow

Periosteum

Dense fibrous membrane covering the surface of a bone

Endosteum

lining of the medullary cavity

Osteon

the structural unit of compact bone

Osteocyte

bone cells found in lucanae

Epiphyseal (growth) plate

Growth plate


Generate new cells until about age 17 when the growing period stops.

Flat bones

Similar in structure in that they consist of two layers of dense bone surrounding a central core of spongy bone called the diploe.


Haversian System (osteons)

Pattern of concentric rings seen in a cross section of compact bone under microscope.


Runs longitudinally through the bone and contains blood vessels, lymph vessels and nerves. Lamellae (rings) encircle the central canal. Within and between the lamellae are lacunae (small spaces) that are interconnected by small channels called canaliculi. Within each lacuna is a bone cell (osteocyte.

Osteocytes

mature bone cells

Osteoblasts

precursor cells atha are responsible for the producation fo new bone in a prcoess called osteogenesis. When completely surrounded by bone matrix it differentiates into an osteocyte. Always adding matrix.

Osteoclasts

giant cells with 50 or more nuclei that function to remove bone matrix.


They secrete acids and exzymes thus dissolving the matrix and releasing stored minerals. Are always removing matrix.

Bone facts

Turnover rate is high: 1/5 of a young adults skeleton is demolished and rebuild or replaced within a year.



> calcium, bone will release it


< calcium, bone will store it.



When stressed, the mineral crystals in bone give off tiny electrical fields which attract osteoblasts and start to produce bone.



Heavily stressed bones become stronger and thicker



Bones without enough stress become thin and brittle

Anulus Fibrosus

Tough outer layer of fibrocartilage

Nucleus Puposus

soft, elastic gelatinous core

Slipped disc

When compression of the nucleus pulposus distort the annulus fibrosus, forcing it partway into the vertebral canal.



Disc does not really "slip"



Whiplash

Herniated disc

Nucleus pulposus breaks through the annulus fibrosus and protrudes into vertebral canal.



Sensory nerves distorted



Painful



May have burning or tingling in lower back and lower limb.


(Partial loss of control over skeletal muscles)

Shoulder joint

*Articulation of head and humerus w/ glenoid cavity of scapula


*Ball and socket joint


*Permits greatest range of motion of any joint


*Most frequently dislocated joint


*Stability sacrificed to obtain mobility


*Stability from surrounding muscles, ligaments and tendons


*"Rotator Cuff" muscles primary support


*Bursae reduce friction

Elbow joint

*Complex hing joint


*Involves humerus, radius and ulna


*Trochlea of humerus articulates with trochlear notch of ulna


*Very stable joint


*nursemaids elbow - partial dislocation caused by pulling a toddler's arm

Hip joint

*Ball and socket joint


*flexion, extension, adduction, abduction, circumduction, rotation


*Acetabulum articulates with head of femur


*Extremely stable joint


*Hip fractures common in elderly w/severe osteoporosis


Knee joint

*Complicated hinge joint


*Flexion, extension, limited rotation


*Medial and lateral menisci- fibrocartilage pads act as cushions and provide lateral stability.


*7 major ligaments stabilize knee joint:


patellar ligament - holds patella


fibular collateral ligament


tibial collateral ligament


anterior cruciate ligament (ACL)


posterior cruciate ligament (PCL)


Popliteal ligaments


*injury common because the knee is a mobile, weight bearing joint, stability depends on associated ligaments and muscles.

"Unhappy triad"

Can result if the foot is planted then blow to side of leg:


Results in "clipping" in football; tibial collateral ligament ruptures, opening the joint on medial side and possibly tearing the medial meniscus and ACL

Synovial joints

Gliding (carpal, tasal)


Hinge (elbow, knee)


Pivot (atlas, axis)


Saddle (carpometacarpal joint of thumb)


Ball-and-socket (shoulder, hip)


Ellipsoidal (Candyloid) (modified ball-and-socket) metacarpophalangeal (knuckle) (except thumb)

Types of movement at synovial joints

Flexion - bending in which angle between 2 bones is decreased


Extension - straightening motion in which angle between bones increases


Abduction - movement of a limb away from the midline of the body; (mvmt. of fingers and toes away from longitudinal axis of the hand or foot)(spreading of fingers)


Adduction - mvmt. of a limb toward the midline of the body. Movement of the fingers or toes toward the midline of the hand and foot. (bringing the fingers back together)


Circumduction - mvmt. in which distal end of bone moves in a circular motion while the proximal end remains stable: as when you move your arm in a large circle.


Rotation - mvmt. of a bone around its longitudinal axis: as when you shake your head no.


Inversion - mvmt. of the sole of the foot inward (medially)


Eversion - mvmt. of the sole of the foot outward (laterally)

Fractures

Complete - the bone breaks completely into 2 pieces.


Incomplete (partial) - The bone does not break completely into 2 or more pieces.


Comminuted - The bone is splintered or crushed into small fragments.


Greenstick - the bone is broken on one side and bent on the other; common in children.


Simple (closed) - The bone is broken but does not break through the skin.


Compound (open) - The bone is broken and cuts through the skin.


Spiral - the bone is broken by twisting


Transverse - the bone is broken directly across at a right angle to the bone's long axis.


Oblique - the bone is broken on a slant, at approx. a 45 degree angle to the bone's long axis.


Chip - the bone is chipped where a protrusion is exposed.


Impacted - the bone is broken when one part is forcefully driven into another, as at shoulder or hip.


Linear Skull - the skull is broken in a line, lenghtwise


Colles' - the distal end of the radius is displaced posteriorly.


Depressed skull - the skull is broken by a puncture, causing a depression below the surface.


Pott's - The distal part of the fibula and medial malleolus of the tibia are broken.

How a fracture heals

1. Bleeding occurs immediately after the fracture and after several hours a fracture hematoma (blood clot) forms.


2. Fibroblasts enter the damaged area and a hard callus forms a few days later.


3. Osteogenic cells differentiate into new bony trabeculae, knitting the new fragments together.


4. Osteoclasts and osteoblasts remodel the region for the many months. This trabecular bone will eventually be replaced w/compact bone. The repaired area may even be thicker and stronger than the original bone and if a similar break occurs it will usually not occur in the same place as the original break.