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69 Cards in this Set

  • Front
  • Back
Pulmonary Circuit
The flow of blood from the heart through the lungs back to the heart
Picks up oxygen and releases carbon dioxide in the lungs
System Circulation:
The flow of blood from the heart through the body back to the heart
Delivers oxygen and picks up carbon dioxide in the body’s tissues
Location, size and shape of the heart
Location
Anterior to the vertebral column, posterior to the sternum
Left of the midline
Deep to the second to fifth intercostal spaces
Superior surface of diaphragm
Shaped like a blunt cone, with an apex and a base
Approximately the size of your fist
Pericardial Sac that encloses the heart:
a double-walled sac around the heart composed of
A superficial fibrous pericardium
A deep two-layer serous pericardium
parietal layer
lines the internal surface of the fibrous pericardium
visceral layer
lines the surface of the heart
pericardial cavity
Parietal and Visceral layer are separated by the fluid-filled (pericardial fluid)
Three Layers of the Heart Wall:
Epicardium
Myocardium
Endocardium
Epicardium
Visceral layer of the serous pericardium (visceral pericardium)
Provides protection against the friction of rubbing organs
Myocardium
Cardiac muscle layer forming the bulk of the heart
Responsible for contraction
Endocardium
Endothelial layer over crisscrossing, interlacing layer of connective tissue
Inner endocardium reduces the friction resulting from the passage of blood through the heart
4 chambers of the heart:
The two ventricles (right and left) are muscular chambers that propel the blood out of the heart (the right ventricle to the lungs, and the left ventricle to all other organs).
The two atria (right and left) hold the blood returning to the heart, and at just the right moment empty into the right and left ventricles.
Atrioventricular (AV) valves
lie between the atria and the ventricles
AV valves prevent backflow into the atria when ventricles contract
Chordae tendineae
anchor AV valves to papillary muscles
Tricuspid valve:
separates the right atrium and ventricle
Bicuspid valve:
separates the left atrium and ventricle
Semilunar valves do what?
prevent backflow of blood into the ventricles
Two types of semilunar valves:
Aortic semilunar valve: lies between the left ventricle and the aorta
Pulmonary semilunar valve: lies between the right ventricle and pulmonary trunk
Route of Blood Flow through the heart: Blood from the body....
flows through the right atrium into the right ventricle and then to the lungs
Route of Blood Flow from the lungs....
Blood returns from the lungs to the left atrium, enters the left ventricle, and is pumped back to the body
Coronary arteries
branch off the aorta to supply the heart
Blood returns from the heart tissues to the right atrium through coronary sinus and cardiac veins
Fibrous Skeleton of the Heart
Consists of a plate of fibrous connective tissue
Forms fibrous rings around the AV and SL valves for support
Provides a point of attachment for heart muscle
Electrically insulates the atria from the ventricles
Cardiac Muscle Cells
Are branched and have a centrally located nucleus
Actin and myosin are organized to form sarcomeres (striated)
T tubules and sarcoplasmic reticulum are not as organized as in skeletal muscle
Normal contraction depends on extracellular Ca2+
Rely on aerobic respiration for ATP production
They have many mitochondria and are well supplied with blood vessels
Joined by intercalated disks
Allow action potentials to move from one cell to the next, thus cardiac muscle cells function as a unit
Action Potentials
(electrical activity of the heart)
After depolarization and partial repolarization, a plateau phase is reached, during which the membrane potential only slowly repolarizes
The opening and closing of voltage-gated ion channels produce the action potential
depolarization
The movement of Na+ through Na+ channels
During depolarization
K+ channels close and Ca2+ channels begin to open
Early repolarization results from ...
closure of the Na+ channels and the opening of some K+ channels
The plateau exists because ...
Ca2+ channels remain open
The rapid phase of repolarization results from
the closure of the Ca2+ channels and the opening of many K+ channels
2 Refractory Periods :
Absolute refractory period
Cardiac muscle cells are insensitive to further stimulation
Relative refractory period
Stronger than normal stimulation can produce an action potential
Why do cardiac muscles relax before AP causes a contraction?
Cardiac muscle has a prolonged depolarization and thus a prolonged absolute refractory period
Some cardiac muscle cells are autorhythmic because ...
spontaneous development of a prepotential
Prepotential: slowly developing local action potential
sinoatrial (SA) node is...
pacemaker of the heart
Collection of cardiac muscle cells capable of spontaneously generating action potentials
Heart rate is determined by...
duration of the prepotential
Prepotential:
slowly developing local action potential
The sinoatrial (SA) node and the atrioventricular (AV) node are in
The RIGHT atrium
The AV node is connected to
the bundle branches in the interventricular septum by the AV bundle
Purkinje fibers:
supply the ventricles and carry the impulse to the heart apex and ventricular walls
What does the SA node initiate?
Action potentials that spread across the atria and cause contraction
Where do the Action potentials slow down?
AV node. This allows atria to contract and blood to flow into the ventricles
atrioventricular bundles
pass the action potentials from atria to ventricles
Where do the AV bundle splits into two pathways ?
interventricular septum
P wave
corresponds to depolarization of the atria (SA node)
QRS complex
corresponds to ventricular depolarization
T wave
corresponds to ventricular repolarization
Atrial repolarization record is masked by the...
QRS complex
ECGs can be used to diagnose
heart abnormailities
Atrial systole
contraction of the atria
Systole
contraction of the ventricles
Atrial diastole
relaxation of the atria
Diastole
relaxation of the ventricles
During systole ( 4 things happen)
AV valves close
Pressure increases in the ventricles
Semilunar valves are forced to open
Blood flows into the aorta and pulmonary trunk
At the beginning of diastole (2 things happen)
Pressure in the ventricles decreases
Semilunar valves close to prevent backflow of blood from the aorta and pulmonary trunk into the ventricles
When the pressure in the ventricles is lower than in the atria
the AV valves open and blood flows from the atria into the ventricles
During atrial systole
the atria contract and complete the filling of the ventricles
3 Events Occurring During Ventricular Systole
1. Ventricular depolarization
2.The volume of blood in a ventricle just before it contracts is the end- diastolic volume
3.The volume of blood after contraction is the end- systolic volume
Ventricular depolarization produces:
the QRS complex
Initiates contraction of the ventricles, which increases ventricular pressure
The AV valves close
Semilunar valves open
Blood is ejected from the heart
Aortic Pressure Curve
Contraction of the ventricles forces blood into the aorta
systolic pressure is
Maximum pressure in the aorta
diastolic pressure is
Minimum pressure in the aorta
Heart sounds (lub-dup) are associated with :
First sound occurs as AV valves close and signifies beginning of systole (lub)
Second sound occurs when SL valves close at the beginning of ventricular diastole (dup)
Mean arterial pressure is
the average blood pressure in the aorta
Cardiac output (CO) is
product of heart rate (HR) and stroke volume (SV)
HR is the number of heart beats per minute
SV is the amount of blood pumped out by a ventricle with each beat
Venous return is
the amount of blood returning to the heart
Starling’s law
describes the relationship between preload and the stroke volume of the heart
An increased preload causes the cardiac muscle fibers to contract with a greater force and produce a greater stroke volume
LaPlace Law
Force=Diameter * Pressure (anurism)
Pousilles law
velocity of a liquid flowing through a capillary is directly proportional to the pressure of the liquid (viscosity as well included)
Ischemia (caused by low CO)
Inadequate blood flow that fails to meet the oxygen demands of tissues
4 Factors that govern CO:
1-preload (volume)
2-Afterload (BP)
3-Cardiac Contractility
4-Pulse rate