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123 Cards in this Set
- Front
- Back
Hierarchy of human complexity (8 levels in order) |
Atoms --> molecules --> organelles --> cells --> tissues --> organs --> organ systems --> organism |
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Characteristics of life (8) |
1. Maintaining boundaries 2. Movement 3. Responsiveness 4. Digestion 5. Metabolism 6. Excretion 7. Reproduction 8. Growth |
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Metabolism |
Sum total of all chemical reactions that occur in the body. |
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Homeostasis (and control mechanisms) |
Relatively stable internal conditions.
Controlled by negative feedback mechanisms (most common) or positive feedback mechanisms. |
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3 planes of the body |
1. Sagittal plane - vertical plane that divides the body into right and left parts. 2. Transverse/Horizontal plane - runs horizontally from right to left dividing the body into superior and inferior parts. 3. Frontal plane - vertical plane dividing the body into anterior and posterior parts. |
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Superior vs. Inferior |
Superior (cranial) - toward the head end or upper part of the body
Inferior (caudal) - away from the head end or toward the lower part of the body |
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Anterior vs. Posterior |
Anterior (ventral) - toward the front of the body
Posterior (dorsal) - toward the back of the body |
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Medial vs. Lateral vs. Intermediate |
Medial - toward the midline of the body
Lateral - away from the midline of the body
Intermediate - between a more medial and a more lateral structure |
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Proximal vs. Distal |
Proximal - closer to the origin of the body part or the point of attachment of a limb to the body trunk
Distal - farther from the origin of a body part or the point of attachment of a limb to the body trunk |
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Superficial (external) vs. deep (internal) |
Superficial (external) - toward or at the body surface
Deep (internal) - away from the body surface more internal |
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The diaphragm separates what two body cavities? |
Thoracic cavity and abdominal cavity |
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What is the smallest part of an element? |
Atom |
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What are the parts of an atom? |
Nucleus - contains protons and neutrons and is positively charged Protons - positive charge, 1 atomic mass unit Neutrons - neutral charge, 1 atomic mass unit Electrons - negative charge, 0 atomic mass unit
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Atomic number |
Equal to the number of protons in an atom's nucleus |
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Mass number |
The sum of the masses of an atom's protons and neutrons |
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Isotopes |
Variations of elements in which there are the same number of protons and electrons but different numbers of neutrons. |
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Atomic weight |
An average of the relative weights or mass numbers of all the Isotopes of an element |
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Electron shells |
The region of space around a nucleus where electrons are. There are 7 possible shells numbered 1 to 7 from the nucleus outward. |
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Octet rule or the rule of eights |
Atoms tend to have eight chemically reactive electrons in their outermost valence shell. |
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Ionic bond |
Involves a transfer of electrons |
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Covalent bond |
Involves a sharing of electrons |
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Anion vs Cation |
During the forming of an ionic bond the atom that gains electrons acquires a negative charge and is called an anion. The atom that loses electrons gains a positive charge and is called a cation. |
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Polar covalent bond vs. Nonpolar covalent bond |
A polar covalent bond has unequal sharing of electrons and a slight negative charge at one end of a molecule and a slight positive charge at the other end. A nonpolar covalent bond has equal sharing of electrons and a balanced charge among atoms. |
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Molecular weight |
The sum of the atomic weights in a molecule |
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Hydrogen bond |
A weak intermolecular attraction between a slightly positive hydrogen atom in one molecule and a slightly negative oxygen or nitrogen in another. |
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Characteristics of water (6) |
1. 50-75% of the body is water 2. Solvency - most substances dissolve in water 3. Cohesion - water molecules "stick" to each other. 4. Adhesion - water "sticks" to other substances. 5. Chemical reactivity - water is important in dehydration synthesis and hydrolysis reactions 6. Thermal stability - water gains and loses heat very slowly. |
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Solutions |
Homogenous mixture of components. Has two parts: solvent (substance present in greatest amount) and solute (substance being dissolved/substance present in smaller amounts). |
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Colloids |
Heterogeneous mixtures who solutes do not settle out |
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Suspensions |
Heterogeneous mixtures with visible solutes that tend to settle out |
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Anabolism |
Synthesis |
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Catabolism |
Decomposition |
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Carbohydrates |
AKA sugars. Includes monosaccharides, disaccharides, and polysaccharides. Most important is glucose which is the body's readily available source of energy. It is stored as glycogen in the liver and skeletal muscles. |
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Lipids |
AKA fats. Includes triglycerides, phospholipids, and steroids. Lipids are hydrophobic. |
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Amino acids |
The building blocks of protein |
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Structural levels of protein |
Primary - amino acid sequence Secondary - alpha helices or beta pleated sheets Tertiary - superimposed folding of secondary structures Quaternary - polypeptide chains linked together in a specific manner |
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Protein denaturation |
When a protein loses its 3D shape. Reversible denaturation is caused by drops in PH and/or increased temperature. Irreversible denaturation is caused by extreme pH or temperature changes. |
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Enzymes |
Enzymes help speed up chemical reactions by putting pieces close enough together for a reaction to happen. |
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Phospholipid bilayer |
Part of the plasma membrane. Includes: Phosphate heads: polar and hydrophilic Fatty acid tails: nonpolar and hydrophobic |
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Functions of membrane proteins (6) |
1. Transport - cells use proteins to bring substances in and for excreting substances from the cell 2. Receptors of signal transduction - these proteins represent the starting point of intracellular messaging 3. Attachment to cytoskeleton and extracellular matrix - anchoring proteins 4. Enzymatic activity - these proteins increase the rate of chemical reactions 5. Intercellular joining - creation of tissues 6. Cell-to-cell recognition - used by the immune system to recognize foreign pathogens |
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Glycocalyx |
Sugar layer around cells that tell your immune system that this cell is yours and it should not attack. |
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Microvilli |
Finger-like projections that serve to increase the surface area of cells. |
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Cilia |
Hairs on cell surface |
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Flagella |
Tails of cells |
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5 main cell types in bone |
1. Osteogenic cells (stem cells) 2. Osteoblasts (bone builders) 3. Osteocytes (embedded in lacunae) 4. Osteoclasts (break down bone) 5. Bone lining cells |
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Ossification (two types) |
1. Endochondral ossification (begins with hyaline cartilage at the ends of long bones) 2. Intermembranous ossification ( begins with mesenchymal cells, usually forms flat bones) |
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Parts of a long bone (8 parts) |
1. Diaphysis: shaft 2. Endosteum: inside lining 3. Epiphyseal plate: growth plate 4. Epiphysis: ends of long bones 5. Periosteum: covering 6. Red marrow: blood cell production 7. Yellow marrow: fat |
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Two types of bone growth |
Interstitial growth: grows and repairs from the inside Appositional growth: grows and repairs from the outside |
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What is the primary mineral found in bone? |
Calcium |
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What are three things involved in calcium homeostasis? |
1. calcitriol (vitamin D) 2. parathyroid hormone (increases calcium in the bloodstream) 3. calcitonin (decreases calcium in the bloodstream) |
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What are the three parts of the axial skeleton? |
1. Skull 2. vertebral column 3. rib cage |
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What are the four components of the appendicular skeleton? |
1. Pectoral girdle 2. Upper Limb 3. pelvic girdle 4. lower limb |
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Bone marking: Projections |
Bone markings that bulge outward from the surface. E.g. heads, trochanter, spines, Etc. |
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Bone markings: Depressions and Openings |
Fossae, sinuses, foramina and grooves |
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Fontanelles |
Membranous areas between cranial bones. Include the anterior fontanelle, the posterior fontanelle, the sphenoidal fontanelle, and mastoid fontanel. |
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Intervertebral disc |
Made of fibrocartilage. Cushionlike pad between the vertebra. |
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Joint classifications by degree of movement: fibrous joints |
1. Syndesmosis - found at the distal end of the tibia, fibula, ulna, and radius 2. Gomphosis - articulation between the teeth and the jaw 3. Sutures - skull bones |
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Joint classification by degree of movement: cartilaginous joints |
1. Synchondrosis: ribs, growth plates 2. Symphysis: intervertebral discs fibrocartilage |
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Joint classification by degree of movement |
1. Synarthrosis- immovable 2. Amphiarthrosis - slightly movable 3. Diarthrosis - freely movable |
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Synovial joint |
Synovial joints have a fluid-filled joint cavity. E.g. hinge joint (elbow), pivot (head), ball-and-socket (hip or shoulder) |
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Types of lever systems |
1. First class (e.g. seesaw) 2. Second class (e.g. wheelbarrow) 3. Third class (e.g. tweezers) |
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5 functional characteristics of muscles |
1. Responsiveness 2. Conductivity 3. Contractility (no other tissue has this) 4. Extensibility 5. Elasticity |
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What are the ends of muscles called? |
The immovable end is called the origin. The movable end is called the insertion. |
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Sarcomere |
Structural unit of muscle.
Components: 1. Sarcolemma: muscle cell membrane 2. Sarcoplasmic reticulum: stores calcium 3. Myofibrils: myosin (thick) and actin (thin) 4. T tubules 5. Glycosomes 6. Myoglobin |
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Regulatory proteins |
1. Tropomyosin (blockade over binding site) 2. Troponin (key to unlock the lock) |
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Power stroke |
Myosin attaches to actin molecules and muscle moves |
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Three types of muscle attachments |
1. Direct muscle attachment (e.g. ribs) 2. Indirect muscle attachment (most common, connect with tendons) 3. Aponeurosis (sheet of tendons) |
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Muscle types by fascicular arrangement |
1. Fusiform 2. Parallel 3. Convergent 4. Pennate - feather like 5. Circular |
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Muscle classification: functional groups |
1. Prime movers -Agonists: primarily responsible for producing movement 2. Synergists: help 3. Antagonists: oppose 4. Fixators: stabilize |
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What is a tendon? |
A cord like extension of muscle |
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7 Ways muscles are named |
1. Muscle location (e.g. temporalis) 2. Muscle shape (e.g. deltoid or trapezius) 3. Muscle size (e.g. gluteus maximus) 4. Directions of muscle fibers (e.g. erectus abdominus or transversus abdominis) 5. Number of Origins (e.g. biceps brachii) 6. Location of the attachments (e.g. sternocleidomastoid) 7. Muscle action (e.g. adductor longus) |
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Nervous system functions |
1. Sensory input (stimulus receptors for pain, pressure, temperature) 2. Integration 3. Motor output |
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Functional classification of neurons |
1. Sensory (afferent) 2. Interneurons (association) 3. Motor (efferent) |
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Structural classification of neurons |
1. Multipolar neurons (99% of all neurons) 2. bipolar neurons (rare, found in special senses) 3. unipolar neurons (sensory neurons) |
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Two types of neuron processes |
1. Dendrites (incoming) 2. Axons (outgoing) |
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What does a synaptic vesicle do? |
Holds neurotransmitters |
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Resting membrane potential (polarization) |
The inside of the cell membrane is more negatively charged than the outside |
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Depolarization |
A decrease in membrane potential: the inside of the membrane becomes less negative than the resting potential. |
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Hyperpolarization |
An increase in membrane potential: the inside of the membrane becomes more negative than the resting potential. |
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Myelin sheath |
Increases the transmission speed of nerve impulses. Formed in the PNS by Schwann cells and in the CNS by oligodendrocytes. |
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Four types of neuroglial cells |
1. Astrocytes: most numerous make blood-brain barrier 2. oligodendrocytes: make myelin in CNS 3. ependymal cells: line the ventricles 4. microglia: phagocytes |
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What is the absolute refractory period? |
The period when a neuron cannot respond to another stimulus. |
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Two types of postsynaptic potentials |
1. Excitatory Postsynaptic Potentials (EPSP) - depolarization 2. Inhibitory Postsynaptic Potential (IPSP) - hyperpolarization |
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Where is cerebrospinal fluid formed and reabsorbed? |
It is formed in the choroid plexus and reabsorbed in the arachnoid Villi |
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Gyri |
Elevation |
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Sulci |
Depression |
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Fissure |
Deep grooves |
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What is the function of the corpus callosum? |
Connects hemispheres so they can operate as a coordinated whole. |
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Five lobes of the cerebrum and their basic functions |
1. Temporal: hearing 2. frontal: personality and motor output 3. parietal: sensory input 4. occipital: Vision 5. insula |
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What is the function of the thalamus? |
It relays incoming sensory information |
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What is the purpose of the hypothalamus? |
It regulates hunger, temperature, sexual response, thirst, etc. |
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What is the cerebellum involved in? |
Motor coordination |
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What are the three parts of the midbrain? |
1. Corpora quadrigemina 2. red nucleus 3. substantia nigra |
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What is the medulla oblongata for? |
It's the decussation center where incoming afferent pathways cross. It controls heart rate, blood pressure, and respiratory rate |
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Name the meninges in order from superficial to Deep |
Dura mater, epidural space, arachnoid Mater, subarachnoid space, Pia Mater |
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Regions of the spine in order from top to bottom |
Cervical enlargement, lumbar enlargement, conus medullaris, cauda equina, filum terminale |
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Spinal tracts |
Ascending (sensory) tracts are three neuron chains going up. Descending motor tracts are two neuron chains going down. |
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How are gray and white matter arranged in the spinal |
Gray matter is on the inside and forms horns and the gray commisure. White matter is on the outside and it forms columns. |
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What is the breakdown of spinal nerves? |
8 cervical 12 thoracic 5 lumbar 5 sacral 1 coccygeal |
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What are the two roots of spinal nerves and their purpose? |
Dorsal root: sensory information in Ventral root: motor output |
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Name the four major nerve plexuses and the primary nerve in each |
1. Cervical plexus - phrenic nerve 2. brachial plexus - arm 3. Lumbar plexus- femoral 4. sacral plexus - sciatic |
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What is a nocireceptor? |
Pain receptor |
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What is a chemoreceptor? |
Detect changes in glucose, oxygen, and hydrogen ion concentration. |
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What do Merkel discs detect? |
Light touch |
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What do meissner corpuscles detect? |
Light pressure |
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What do lamellar corpuscles detect? |
Deep pressure |
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What are the effectors of the autonomic nervous system? |
It controls the heart, smooth muscles, and glands. |
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What is the sympathetic division known for? |
Fight or flight |
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What is the parasympathetic division known for? |
Resting and digesting |
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What are cholinergic fibers? |
Axon terminals that release acetylcholine. |
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What are adrenergic fibers? |
Axon terminals that release norepinephrine. |
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What are cholinergic receptors? |
Acetylcholine binds to them |
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What are adrenergic receptors? |
Norepinephrine binds to them |
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What are the primary receptors for taste (gustation)? |
Taste hairs |
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The primary receptors for smell (olfaction)? |
Olfactory cells which are bipolar neuron receptors |
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Where are the primary receptors for hearing? |
Cochlea |
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What picks up sensory hearing input? |
Temporal lobe |
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What is the vestibular apparatus? |
The collective term for equilibrium receptors. |
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What is the Crista ampullaris? |
Dynamic equilibrium receptor |
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What is the macula? |
Static equilibrium receptor |
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What are the three layers of the eye and what is located in each? |
Fibrous layer: (outer layer) includes sclera and cornea Vascular layer: this is where the blood supply is. Includes choroid, ciliary body and Iris Inner layer: retina |
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What is the aqueous humor? |
The anterior segment of the eye |
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What is the vitreous body or vitreous humor? |
The posterior segment of the eye |
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What are the two types of photoreceptors and what do they see? |
Rods: black and white receptors, give vision in dim light Cones: color receptors, they require lots of light |