Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
41 Cards in this Set
- Front
- Back
Which connective tissue coat surrounds groups of muscle fibers, separating them into fascicles?
|
Perimysium bundles groups of muscle fibers into fascicles.
|
|
Which of the following is the smallest: muscle fiber, thick filament, or myofibril? Which is largest?
|
smallest-largest: thick filament, myofibril, muscle fiber
|
|
How are sarcomeres separated from each other?
|
Sarcomeres are separated from one another by Z discs.
|
|
Which proteins connect into the Z disc? Which proteins are present in the A band? In the I band?
|
Actin and titin anchor into the Z discs. A bands contain myosin, actin, troponin, tropomyosin, and titin; I bands contain all but myosin.
|
|
What happens to the I band and H zone as muscle contracts? Do the lengths of the thick and thin filaments change?
|
The I bands and H zones disappear during muscle contraction; the lengths of the thin and thick filaments do not change.
|
|
What would happen if ATP suddenly were not available after the sarcomere had started to shorten?
|
If ATP were not available, the crossbridges would not be able to detach from actin. The muscles would remain in a state of rigidity, as occurs in rigor mortis.
|
|
What are the three functions of ATP in muscle contraction?
|
1. Its hydrolysis by an ATPase activates the myosin head so it can bind to actin and rotate; 2. its binding to myosin causes detachment from actin after the power stroke; 3. it powers the pumps that transport Ca2+ from the cytosol back into the sarcoplasmic reticulum (SR)
|
|
Why is tension maximal at a sarcomere length of 2.2 um?
|
A sarcomere length of 2.2um gives a generous zone of overlap btwn the parts of the thick filaments that have myosin heads and the thin filaments without the overlap being so extensive that sarcomere shortening is limited.
|
|
What part of the sarcolemma contains acetylcholine receptors?
|
the motor end plate
|
|
Where inside a skeletal muscle fiber are the events shown here occurring?
|
Glycolysis, exchange of phosphate btwn creatin phosphate and ADP, and glycogen breakdown occur in the cytosol. Oxidation of pyruvic acid, amino acids, and fatty acids (aerobic cellular respiration) occurs in mitochondria.
|
|
What is the effect of the size of a motor unit on its strength of contraction?
|
Motor units having many muscle fibers are capable of more forceful contractions than those having only a few fibers.
|
|
What events occur during the latent period?
|
During the latent period, the muscle action potential sweeps over the sarcolemma and calcium ions are released from the sarcoplasmic reticulum (SR)
|
|
Would the peak force of the second contraction be larger or smaller if the second stimulus were applied a few milliseconds later?
|
If the second stimulus was applied a little later, the second contraction would be smaller than the one illustrated.
|
|
What type of contraction occurs in your neck muscles while you are walking?
|
mainly isometric contractions
|
|
Which type of smooth muscle is more like cardiac muscle than skeletal muscle, with respect to both its structure and function?
|
Visceral smooth muscle is more like cardiac muscle; both contain gap junctions, which allow action potentials to spread from each cell to its neighbors.
|
|
How does the speed of onset and duration of contraction in a smooth muscle fiber compare with that in a skeletal muscle fiber?
|
Contraction in a smooth muscle fiber starts more slowly and lasts much longer than a contraction in a skeletal muscle fiber.
|
|
Which part of a somite differentiates into skeletal muscle?
|
The myotome of a somite differentiates into skeletal muscle.
|
|
Where is the belly of the muscle that extends the forearm located?
|
The triceps brachii is located posterior to the humerus
|
|
How does the inferior oblique muscle move the eyeball superiorly and laterally?
|
b/c it originates at the anteromedial aspect of the floor of the orbit and inserts on the posterolateral aspect of the eyeball.
|
|
Which is the strongest muscle of mastication?
|
The masseter is the strongest chewing muscle.
|
|
What are the functions of the tongue?
|
chewing, tasting, swallowing, and speech
|
|
Which abdominal muscle aids in urination?
|
rectus abdominis muscle aids in urination
|
|
Which muscle associated with breathing is innervated by the phrenic nerve?
|
The diaphragm is innervated by the phrenic nerve.
|
|
Which tendons make up the rotator cuff?
|
consists of the flat tendons of the subscapularis, supraspinatus, infraspinatus, and teres minor muscles that form the nearly complete circle around the shoulder joint.
|
|
Which muscles are the most powerful flexor and the most powerful extensor of the forearm?
|
The brachialis is the most powerful forearm flexor; the triceps brachii is the most powerful extensor.
|
|
Muscles of the thenar eminence act on which digit?
|
Muscles of the thenar eminence act on the thumb.
|
|
What is the approximate volume of blood in your body?
|
Blood volume is about 8% of body mass; 5-6L in males, and 4-5L in females
|
|
Which formed elements of the blood are cell fragments?
|
Platelets are cell fragments
|
|
From which connective tissue cells do pluripotent stem cells develop?
|
Pluripotent stem cells develop from mesenchyme.
|
|
How many molecules of O2 can one hemoglobin molecule transport?
|
One hemoglobin molecule can transport a max. of four O2 molecules, one O2 bound to each heme group.
|
|
What is the function of transferrin?
|
Transferrin is a plasma protein that transports iron in the blood.
|
|
How might the hematocrit change if you moved from a town at sea level to a high mountain village?
|
Once you moved to high altitude your hematocrit would increase due to increased secretion of erythropoietin.
|
|
Which WBCs are called granular leukocytes? Why?
|
Neutrophils, eosinophils, and basophils are called granular leukocytes b/c all have cytoplasmic granules that are visible through a light microscope when stained.
|
|
In what way is the “traffic pattern” of lymphocytes in the body different from that of other WBCs?
|
Lymphocytes recirculate from blood to tissues adn back to blood. After leaving the blood, other WBCs remain in the tissues until they die.
|
|
Along with platelet plug formation, which to mechanisms contribute to hemostasis?
|
Along with platelet plug formation, vascular spasm and blood clotting contribute to hemostasis.
|
|
What is serum?
|
Serum is blood plasma minus the clotting proteins.
|
|
What is the outcome of the first stage of blood clotting?
|
First stage of clotting is the formation of the prothrombinase.
|
|
Which antibodies are usually present in type O blood?
|
Type O blood usually contains both anti-A and anti-B antibodies.
|
|
Why is the firstborn baby unlikely to have HDN?
|
B/c the mother is likely to start making anti-Rh antibodies after the first baby is already born, that baby suffers no damage.
|
|
What is agglutination?
|
the clumping of red blood cells.
|
|
What are some symptoms of sickle-cell disease?
|
Anemia, mild jaundice, joint pain, shortness of breath, rapid heart rate, abdominal pain, fever, fatigue
|