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65 Cards in this Set

  • Front
  • Back

___________ control is fast but short-lived


(on or off - instantaneous)

Nervous

_____________ control is slow and last a long time


(chemical)

Chemical

7 Organs of the endocrine system

Hypothalamus


pituitary (hypophysis)


thyroid


parathyroid


adrenal


pineal


thymus

Organs that have more than one role

pancreas


testis


ovary

Produces digestive enzymes, insulin and glucogone

Pancreas

the testies and ovaries are also known as the ___________.

Gonads

Produce gamates, sperm and eggs

Gonads

2 main classes of hormones based on how they are built

Amino-acid based


Steroid based

Most hormones are ______________ based.

Amino-acid

_________ hormones are water based and they like water because they are polar

Amino acid-based

______________ based hormones are synthesized from cholesterol

Steroid

Target cell specificity refers to.....





Hormones circulate throughout body, but only affect cells that have receptors for that hormone

If hormone level is low, cells produce more receptors to become more sensitive

Up regulation

If hormone level is high, cell may decrease number of receptors (taking away receptors)

Down-regulation

A cell that has the receptors that a particular hormone is attaching to is called the __________________

Target cell

5 cell effects resulting from mechanism of hormone action

alters membrane permeability


Stimulates protein synthesis


Enzyme activity


Secretory activity


Cell division

example of how hormones alter permeability

Ions

Example of hormones stimulating protein synthesis

enzymes, collagen

Example of hormones activating or deactivating enzyme activity

Prolactin - mamory gland

Example of hormones activating secretory activity

increasing the activity level of glands

Example of hormones activating cell division

increase rate of mitosis

2nd messenger

cAMP


cyclic AMP

Is cAMP steroid or amino acid based?

Amino acid

5 steps for 2nd messenger system

1st messenger (hormone) binds to receptor


G protein is activated


Active g protein activates adenylate cyclase


Adenylate cyclase turns ATP into cAMP


cAmp activates protein kinases (which in turn activates or deactivates some enzymes)



2 mechanisms of hormone action

2nd messenger system


Direct gene activation

Hormone mechanism of action where steroids easily diffuse thru membrane, bind to inracellular receptor and then the hormone/receptor complex is transported to the nucleus, attaches to DNA and activates gene.

Direct gene activation

Most hormones of the body are under ________ feedback control

negative

True or False




the nervous system can override the hormonal system eg: fight/flight

True

3 methods of that stimulate hormonal release

Hormonal


Humoral


Neural

Another hormone control the gland's release of hormone

Hormonal stimuli

3 types of hormonal stimuli

RH - releasing hormone


IH - inhibiting hormone


tropic hormones that control other endocrine organs

the hormonal stimuli is triggered by the level of something in the body fluids control gland

Humoral

stimuli causing a hormonal release by the nervous system - epi and nor-epi

Neutral

8 organs of the endocrine system

Pituitary (hypophysis)


Thyroid


Parathyroid


Adrenal


Pancreas


Thymus

attached by talk (infundibulum) to the inferior side of the brain

Pituitary (hypophysis)

2 main lobes of the pituitary

Anterior adenohypophysis


Posterior neurohypophysis

5 hormones released by the adenohypophysis

Growth hormone GH


Thyroid stimulating hormone (TSH)


Adrenocorticotropic hormone (ACTH)


Gonadotropins


Prolactin

GH

growth hormone

TSH

thyroid stimulating hormone

ACTH

adenocorticotropic hormone

children have increased levels causing mitosis in general body tissues

growth hormone

Stimulates the thyroid that releases thyroid hormone

TSH

Is TSH tropic?

yes

Controls adrenal cortex

Adrenocorticotropic hormone

2 kinds of gonadotropins that control ovaries and testies

FSH


LH

is prolactin tropic or not?

not

neural control of pituitary

Posterior lobe aka neurohypophysis

In neurphypophysis cell bodies of neurons are in the __________________ and endings are in the ______________.

hypothalamus


Neurohypophysis

glial like cells forun in the neurohypophysis

pituicytes

portion of the pituitary that stores hormones

posterior lobe

2 hormones stored in neurohypophysis

ADH - antidiuretic hormone


Oxitocin

If in the dessert ADH is high or low?

High, it instructs the kidneys to retain water

Stimulates contraction of smooth muscle in uterus and breast

Oxytocin

Is the release of oxytocin positive or negative feedback?

positive

Overlies the trachea and is inferior to the larynx

Thyroid

The structure of the thyroid is a ___________

follicle

True or False


Thyroid that controls calcitonin, regulating Ca++ balance. Decrease in blood Ca++ stimulates osteoblasts and humoral control

True

4 hidden in the posterior thyroid gland

Parathyroid glands

In the parathyroid gland small chief cells produce

PTH

PTH increases blood ca++ stimulating ____________. It is the single most important factor in ______ Ca++ control.

osteoclasts


adult

function of oxyphil cells

unclear

Located in the fat above each kidney

Adreanal glands

The adrenal gland is the size of ________

the tip of a finger

3 layers of zona of the adrenal cortex

Zona glomerulosa


Zona fasciculata


Zona reticularis

mineralocorticoids - ion blance

zona glomerulosa