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82 Cards in this Set

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What are endocrine glands?

Glands that produce and secrete hormones into the bloodstream.

What are exocrine glands?

Glands that secrete chemicals for elimination.

What are hormones?

Specialized substances that regulate many body functions.

What is a prostaglandin?

A group of hormone-like fatty acids


Cause uterine contractions, regulation for blood pressure, smooth muscle contraction and pain and inflammation.

Do corticosteroids and thyroid hormones bind to receptors on the inside or outside of cells?

Inside


All other hormones bind to outside receptors

What is negative feedback?

The concept that once the desired effect of the hormone is achieved further production of that hormone is inhibited until it is needed again.

Negative feedback is also called _________.

Feedback inhibition

What is positive feedback?

The concept that once the desired effect of the hormone begins, further production of that hormone is stimulated.

Which gland is called the master gland and where is it found?

The pituitary gland


The base of the brain

What regulates the function of the pituitary gland?

The hypothalamus

What are hormones produced by the neurohypophysis called?

Neurohormones

What are the two major hormones stored and secreted by the neurohypophysis?

Antidiuretic hormone


Oxytocin

In high concentrations what does an antidiuretic hormone do to the body?

Constricts blood vessels and raises BP

What does an antidiuretic hormone cause in the kidneys?

Promotes water retention and reduction in urine volume.

What does oxytocin do?

Causes the smooth muscles of the pregnant uterus to contract and milk to be released from the breast of a lactating women.

What is the anterior pituitary gland called and why are their hormones not called neurohormones?

Adenohypophysis


Because it is not considered part of the CNS

What is the growth hormone called?

Somatotropin

What does somatotropin do?

Stimulates growth especially in long bones


Increases protein synthesis and the use of fats for energy


Stimulates production of protein in liver and skeletal muscle

What releases growth hormone-releasing hormone and growth hormone-inhibiting hormone?

Hypothalamus

What is the thyroid-stimulating hormone called?

Thyrotropin

What is ACTH and what does it do?

Adrenocorticotropic hormone


Essential in development of the cortex of the adrenal gland and its secretion of corticosteroids steroids

What hormones regulates the production of both egg and sperm as well as production of reproductive hormones?

Luteinizing hormone and follicle stimulating hormone

Both are under the influence of ganadotropin-releasing hormone

Which hormone plays an important role in milk production in women?

Prolactin

Helps in sperm production in men

Where is the thyroid gland and how many lobes does it have?

Below the larynx


2 lobes

What is the band of tissues called that connects the two lobes of the thyroid gland?

Isthmus

What do the hormones that the thyroid secretes do?

Hormones that influence growth, development and metabolism

Where can you find thyroglobulin and what does it do?

In the follicles of the thyroid gland


A protein that binds thyroid hormones

Where can you find calcitonin and what does it do?

In the parafollicular cells between the follicles of the thyroid glands


Important in regulating calcium levels in the body

What are the two major hormones produced by the thyroid?

T³ triiodothyronine


T⁴ tetraiodothyronine

Produced when the anterior pituitary gland is stimulated by thyroid stimulating hormone


Where are the parathyroid glands located?

Posterior thyroid gland surface

Is the pancreas a exocrine or an endocrine gland and how?

Exocrine when secreting digestive juices


And


Endocrine when releasing hormones (insulin and glucagon)

What does insulin do?

Causes sugar, fatty acids, and amino acids to be taken up and metabolized by cells.

What does glucagon do?

Stimulated the breakdown of glycogen to glucose


Also cause the liver and kidney to produce glucose from non carbohydrate sources (gluconeogenesis).

Where are the adrenal glands located and what do they do?

On top of the kidneys


Manufacture and secrete sex hormones as well as hormones vital in maintaining the body's water and salt balance.

What do the adrenal glands secrete?

Adrenaline and corticosteroids

What are the reproductive glands?

Ovaries in women


Testes in men

What (is,are) the major reproductive hormones in men and women

Men-testosterone


Women-estrogen, progesterone, human chorionic ganadotropin.

Where is the pineal gland located and what hormone does it secrete?

Deep in the cerebral hemispheres


Secretes melatonin in response to light conditions

What does aldosterone do?

Increases the rate of active reabsorption sodium and chloride ions into the blood and decreases the reabsorption of potassium.

What are alpha cells?

Cells located in the islets of Langerhans that secrete glucagon.

What are anabolic steroids?

Synthetic adrogens used to increase muscle mass

What are adrogens?

Male sex hormones

What is vasopressin?

ADH


Constricts blood vessels and raises BP

What are beta cells?

Cells located in the islets of Langerhans that secrete insulin.

What are beta endorphins and what do they do?

Protein produced in the hypothalamus and anterior pituitary


Have same effects as opiate drugs such as morphine but are 80x more potent

What are circadian rhythms?

Help the body distinguish day from night

What is Conn syndrome?

A condition that results in the excess secretion of aldosterone

Commonly caused by a benign tumor

What is the most important steroid created by the adrenal glands?

Cortisol

What is Cushing syndrome?

A condition caused by the excessive production of cortisol


Results in obesity,moon face, high BP, abnormal hair growth.

How does diabetes insipidus and mellitus differ?

Insipidus is a pituitary gland disorder that causes large productions of dilute urine


Mellitus is an impaired production of insulin by the pancreas

What is exophthalmos?

Protrusion of the eyes from the normal position within the socket

What is a goiter?

Enlarged visible mass in the anterior part of the neck caused by enlargement of the thyroid gland

What are hormone-sensitive lapase and what do they do?

Enzyme activated by glucagon


Breaks triglycerides down into free fatty acids and glycerol.

What is hyperparathyroidism?

When there is an excess secretion of parathyroid hormones there is a loss of calcium from the bones and an increase in serum calcium levels

What is hyperthyroidism and what side effects does it have?

Over activity of the thyroid gland


Increased metabolic rate, weight loss, rapid pulse, elevates BP, diarrhea, and sometimes bulging eyes

What is hypophysis?

The gland that secretes hormones that regulate the function of many other glands in the body

Also called pituitary glands

What are releasing factors and what I'd another name for them?

Compounds that travel from the hypothalamus to the pituitary gland in a specialized set of blood vessels.


Also called inhibiting factors

What is the hypothalamohypophyseal portal system?

The specialized set of blood vessels that carry releasing factors from the hypothalamus to the anterior pituitary.

What is the infundibulum?

The stalk that connects the hypothalamus and the pituitary gland.

What is another name for adenohypophysis?

Anterior pituitary (lobe)

What is another name for the neurohypophysis?

Posterior pituitary (lobe)

What are the two divisions of the pituitary gland?

Anterior and posterior.

How does the posterior pituitary gland differ from the anterior pituitary?

It is made up mostly of nerve fibers and neuroglial cells

What is another name for ADH?

Vasopressin

What are osmoreceptors?

Specialized neurons in the brain that regulate the secretion of ADH

Growth hormone stimulates the production of a protein. What is that protein?

Somatomedins

What is another name for growth hormone-release inhibiting hormone?

Somatostatin

What does somatostatin do?

Inhibits the release of GH.

What are corticosteroids?

Any if several steroids secreted by the adrenal glands.

Which hormone stimulates the release of LH and FSH?

Gonadotropin-releasing hormone

Where are prolactin-releasing hormones and prolactin-inhibiting hormones realeased?

Hypothalamus

Just know!

The thyroid has 2 lobes


Connected by isthmus


Covered by connective tissue w/secrtory parts called follicles


Filled with clear substance called colloid


Colloid stores hormones produced by follicles

What is thyroxine-binding globulin?

Protein synthesized by the liver that binds to hormones T3 and T4

What does parathyroid hormone do?

Maintain normal levels of calcium in blood and normal neuromuscular function

What is gluconeogenosis?

The production of glucose from noncarbohydrate molecules

What is hormone-sensitive lipase?

An enzyme that is activated by glucagon.

Breaks triglycerides down into free fatty acids and glycerol.

Where is epinephrine and norepinephrine produced?

Medulla of the adrenal glands.

What are the zones of the adrenal cortex?

Zona glomerulosa


Zona fasciculata


Zona reticularis

Just know!

Zona glomerulosa produces mineralocorticoids (hormones in regulating the water and salt balance)


Most important mineralocorticoid is aldosterone.

Just know!

Zona fasciculata


Glucocorticoids


Cortisol

Just know!

Zona reticularis


Androgens


Androstenedione

What is the hypothalamic pituitary adrenal axis?

Regulates the secretion of corticosteroids