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21 Cards in this Set
- Front
- Back
Physical elements of blood
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both solid and liquid elements, 55% Plasma, PH between 7.35-7.45, Accounts for 8% of body weight. males 5-6L of blood
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Hematocrit
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%of erythrocytes in formed element portion of blood (remaining 45% of blood, without plasma) 45%
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Red Blood Cells, RBC
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4-6 million
Transport o2 and CO2, Biconcave discs, Lacks mictchondria, 5 million cells per mm3, anucleated |
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Hemoglobin (Hb)
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Found on RBC's to transport O2, each RBC contains aprox 250mill hemoglobin molecules, each capible of binding 40 molecules of O2. Norm Bl Count 12-18Grams/100mm(ml) blood
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Life of RBC
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5-7 days for development, Lives for 120 days
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Pernicious
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Lack of Vit B12
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Leukocytes
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4000-11000 WBC's/mm3
accounts for less than 1% of total blood vol. |
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Diapedesis
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ability of WBC's to slip thru cell membranes
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Chemotaxis
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WBC's moving to needed site
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Granulocytes
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Granule containing WBC's:
Neutrophils Basophils Eosinophils |
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Neutrophils
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Multilobed nucleus
granulocyte phagocytosis used in infections |
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Basophils
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Rarest WBC, Release HISTAMINE
Granulocyte |
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Eosinophils
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ALLERGIC REACTIONS, and PARASITES
Granulocyte |
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Agranlocytes
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monocytes- phagocytes
lymphocytes-secrete antibodies |
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Lymphocytes
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Agranulocytes, tend to live in Lymph tissue, Plays role in immune response
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Monocytes
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Largest of WBC's, indented nucleus, macrophages with huge appetites, fight chronic infection
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Leukocytosis vs Leukopenia
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cytosis- over 11,000 cells/mm
penia- abnormally low WBC's |
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Megakaryocytes
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Bizarre Multinucleated cells, pinch off thousands of anucleated platelet peices
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3 Phases of Hemostatsis
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-Stoppage of blood
1. Platelet formation of plug 2. Vascular spasms occur 3. Coagulation occurs prothrombin, fibrin etc |
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Coagulation
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Clotting; Injured tissue releases (TF)tissue factor, PF3 interacts with TF, Vit K and CA, that activates prothrombin to thrombin. Thrombin joins to fibrinogen= Fibrin that traps cells and makes clot
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Agglutination
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Binding of antibodies cause RBC's to clump which leads to the clogging of small blood vessels throughout the body
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