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9 Cards in this Set
- Front
- Back
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Pre krebs |
Pyruvate is converted to CoA in 3 steps: 1) pyruvates carboxyl group is removed and given off as CO2 2) the remains become oxidized, forming acetate; the extracted electrons are transferred to NAD+ storing energy in the form of NADH 3) CoA attaches to the acetate, forming acetyl CoA |
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Krebs cycle 1 |
Acetyl CoA adds its 2 carbon acetyl group to oxaloacetate, producing citrate |
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Krebs cycle 2 |
Citrate converted to its isomer by the removal of one water molecule and addition of another |
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Krebs 3 |
Isocitrate is oxidized, reducing NAD+ to NADH. Then the resulting compound loses a CO2 molecule |
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Krebs 4 |
Another CO2 is lost, and the resulting compound is oxidized, reducing NAD+ to NADH. The remaining molecule is then attached to coenzyme A by an unstable bond |
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Krebs 5 |
CoA is displaced by a phosphate group, which is transferred to GDP, forming GTP, a molecule with functions similar to ATP. FTP can also be used, as shown, to generate ATP |
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Krebs 6 |
2 hydrogens are transferred to FAD, forming FADH2, and oxidizing succinate |
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Krebs 7 |
Addition of water molecule rearranges bonds in the substrate |
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Krebs 8 |
The substrate us oxidized, reducing NAD+ to NADH and rearranging oxaloacetate |
