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29 Cards in this Set

  • Front
  • Back
5 causes of hypoxemic hypoxia
High altitude
Obstructive pulm disease
Fibrotic lung disease
Pulmonary edema
2 causes of hypoperfusion hypoxia
high PEEP
What abnormal lab finding indicates hypoperfusion hypoxia
decreased PVO2
3 causes of anemic hypoxia
decreased RBC
decreased hgb in RBCs
CO poisoning
2 causes of histotoxic hypoxia
cyanide poisoning
nipride poisoning
VCO2 at rest
CO2 per 100 mL blood passing through the tissues
4 mL CO2
Solubility coefficient of CO2
0.063 ml/ 100ml/ torr
% CO2 transported to the lungs in the dissolved state
Where does CO2 bind on the plasma protein
Terminal amine
PCO2 at the tissue level
45-48 torr
In the lungs pO2 increases and decreases the Hgb affinity for CO2
Haldane effect
Catalyzes the formation of carbonic acid from CO2 and H2O in the RBC
carbonic anyhydrase
Two ways that venous labs will differ from arterial labs d/t CO2 entering the RBC
increased HCT
decreased pH
% of CO2 transported as bicarbonate dissolved in plasma
% of CO2 transported as carbamino compounds
% of CO2 dissolved in plasma
For a given change in O2 or CO2 tension, which has the greater change in blood content
What is the respiratory exchange ratio
ratio of CO2 output/O2 uptake in the lungs 0.8
What does consuming carbohydrates do to RE
increases it to 1

1:1 ratio
What does consuming fats do to RE
decreases it to 0.7

1:1.4 ratio
What is the respiratory quotient
CO2 production/ O2 consumption at the level of the tissues 0.8
Is RE or RQ greater during exercise
Will hypoxemia always lead to hypoxia
no because CO can compensate to a point
Hypoxic conditions caused by inadequate amounts of O2 content in the blood
4 major causes of hypoxemia
diffusion limitation
V/Q mismatch
Where do H+ ions come from in the venous blood
release from carbamino compounds
release from carbonic acid breakdown
What displaces oxygen attached to Hgb at the level of the tissues
H+ ions
decreased affinity d/t CO2
What displaces H+ attached to Hgb at the level of the lungs
O2 molecules