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43 Cards in this Set

  • Front
  • Back
What hormones does the pancreas produce? What are their functions?
1) Alpha (A cells)
-glucagon: increase blood sugar

2) Beta (B cells)
-Insulin: decrease blood sugar

3) Delta (D cells)
-Somatostatin (GHIH): stops secretion of insulin, glucagon, GHIH

4) F cells
-Pancreatic Polypeptide: stop secretion of all enzymes made by pancreas
Which stem cells become lymphocytes? Myeloid or Lymphoid?
Lymphoid
What will megakaryocytes become?
Platelets
List the hormones of the adenohypophysis and their releasing hormones from the hypothalamus.
- hGH --> GHRH
- TSH --> TRH
- FSH --> GnRH
- LH --> GnRH
- PRL --> PRH
- ACTH --> CRH
- MSH --> CRH
List all steps to Renin- Angiotensin- Aldosterone.
1) Renin converts Angiotensinogen to angiotensin I
2) Angiotensin I converted to Ang II by Angiotensin Converting Enzyme (ACE Inhibitor)
3) Ang II is Vasoconstrictor and cause release of aldosterone
4) Aldosterone causes increase Na+ = increase blood vol = increase blood pressure
Name two antagonist hormones. Explain what each antagonist hormone does.
Insulin & Glucagon

-Insulin: lower blood sugar
-Glucagon: raises blood sugar
What blood type is the universal donor? Universal recipient?
-Universal Donor: Type O
-Universal Recipient: AB
Where are the antagonist hormones manufactured
Insulin and glucagon are manufactured in the pancreas.
How are the thyroid hormone made?
1) Follicular cell pulls iodide out of the blood
2) Turn 2 I to I2 then puts it into the colloid
3) Follicular cells make TGB and put it into the colloid
4) TGB + Iodine = T1 and T2
5) T1 and T2 pair up to make T3 and T4
6) T3 and T4 secrets back into the blood by riding on (TBG) transport protein
What does an elevated TSH level indicated?
Hyperthyroid
Besides vascular spasm, what are the other two ways the blood loss can be controlled. Explain their pathways.
-Platelets & Coagulation

-Platelets: have three chemicals ADP, Thromebarne A2, & serotonin
*ADP&Thromebarne A2 make platelets sticky
* Thromebarne A2 & serotonin act as a vasoconstrictor

-Coagulation: Prothrobinase converts prothrombin to thrombin, thrombin converts to fibrinogen to fibrin
List the five leukocytes. What does an increase level of each indicate?
Neutrophil- bacterial Granular
Leukocyte- viral
Monocytes- Fungi,TB
Eosinophil- parasite
Basophil- cancer, hypothyroid
What is leukopenia?
<5,000 WBC
How long is the life of an erythrocyte? Where are they produced?
-120 days (4 months)
-They're produced in the red bone marrow
What is the fate of hemoglobin?
*Hemoglobin splits into two parts: heme & globin

*Globin recycles the amino acids (protein).

*Heme has two parts: iron & pigment
-Iron: Transferrin transports iron to the ferritin, picks that up later and recycle it in the red bone marrow
-Pigment: (cannot be recycled) Biliverdin and bilirubin turns into urobilinogen and it breaks up into sterobin (feces) and urobilin (urian)
What is hemolytic disease of the newborn?
When a Rh- mother has an Rh+ fetus. Her body builds antibodies to attack the fetus. The 1st baby dies but rest live
What is plasma mainly composed of? What are the plasma proteins and their functions?
- Mainly composed of water

Plasma Proteins
-Albumin: transport
-Globulin: immunity
-Fibrinogen: make blood clotsa
Atenolol is a commonly known beta block, which are receptors for epinephrine. How does this help with hypertension?
....
Which pituitary hormones work on negative feedback system?
-TSH
-FSH
-LH
-ACTH
-MSH
Cell Mediated
(T cell)
1) A macrophage eats antigens
2) The antigen is presented on the surface of the macrophage in MHC II
3) A helper T cell w/ the same antibody on surface binds to the MHC II containing the antigen
4) Helper T cell then activates cytotoxic T cells
5) Cytotoxic T cells then patrol the body looking for other infected cell
6) When cytotoxic T cell finds an infected cell, it binds to the MHC I receptor containing the antigen present on the surface
7) Cytotoxic T cells will then release Interferon to slow down the infected cell's reproduction, later causing cell to undergo apoptosis
Cell Mediated
(T cell)
1) A macrophage eats antigens
2) The antigen is presented on the surface of the macrophage in MHC II
3) A helper T cell w/ the same antibody on surface binds to the MHC II containing the antigen
4) Helper T cell then activates cytotoxic T cells
5) Cytotoxic T cells then patrol the body looking for other infected cell
6) When cytotoxic T cell finds an infected cell, it binds to the MHC I receptor containing the antigen present on the surface
7) Cytotoxic T cells will then release Interferon to slow down the infected cell's reproduction, later causing cell to undergo apoptosis
Antibody-Mediated
(B Cells)
1) B cells, have antibodies attached to their surface which, will bind to an antigen floating around the blood
2) The antigen subsequently presents on the B cell surface in a MHC II receptor
3) A helper T cell containing the same antibody will bind to MHC II receptor
4) Causing the B cell to differentiate into plasma cells and memory cells
5) Plasma cells generate free floating antibodies, memory B cells stay around in case of later infection
Cell Mediated
(T cell)
1) A macrophage eats antigens
2) The antigen is presented on the surface of the macrophage in MHC II
3) A helper T cell w/ the same antibody on surface binds to the MHC II containing the antigen
4) Helper T cell then activates cytotoxic T cells
5) Cytotoxic T cells then patrol the body looking for other infected cell
6) When cytotoxic T cell finds an infected cell, it binds to the MHC I receptor containing the antigen present on the surface
7) Cytotoxic T cells will then release Interferon to slow down the infected cell's reproduction, later causing cell to undergo apoptosis
Antibody-Mediated
(B Cells)
1) B cells, have antibodies attached to their surface which, will bind to an antigen floating around the blood
2) The antigen subsequently presents on the B cell surface in a MHC II receptor
3) A helper T cell containing the same antibody will bind to MHC II receptor
4) Causing the B cell to differentiate into plasma cells and memory cells
5) Plasma cells generate free floating antibodies, memory B cells stay around in case of later infection
Which type of cell assists in both these processes?
Helper T Cell
Name four different types of organisms that can infect a person. Which one of them is endogenous?
A) -Virus
-Parasites
-Fungus
-Bacteria

B) Virus
List the flow of blood through the heart include the lungs and tissues (cells). Identity which carry oxygenated blood.
Rt Atrium ➡️ Tricuspid Valve ➡️ Rt Ventricle ➡️ Pulmonary Valve ➡️ Pulmonary Truck ➡️ Pulmonary Arteries ➡️ Lungs (Deoxygenated) ➡️ Pulmonary Veins ➡️ Lt Atrium ➡️ Mitral Valve ➡️ Lt Ventricle ➡️ Aorta Valve ➡️ Aorta ➡️ Arteries Tissue ➡️ Veins ➡️ Vena Cava ➡️ Rt Atrium
What factors contribute to heart rate? Include chemical and neurological.
...
What factor regulate stroke volume? List them and explain.
....
What factors contribute to heart rate? Include chemical and neurological.
Neurological:
-Beroreceptors- Blood pressure
-Chemoreceptors- Monitor chemicals
-Proprioreceptors- Monitor Limb movement
ANS- vagus nerve (x)

Chemical:
-Epinephrine
-Na+, K+ decrease heart rate & contractility
-Ca+ increase heart rate
What factor regulate stroke volume? List them and explain.
Preload: Amount of stretching in ventricle

Contractility: Forcefulness of contraction

Afterload: Amount of pressure exceeded before ventricular ejection
What are the other names for deep and shallow breathing? What are two factors responsible for increasing the volume capacity of the lungs?
A) -Diaphragnic 75%
-Costal 25%

B) -Diaphragan
-External Intercostal
What are the three laws pertaining to respiration? Explain them.
-Boyle's Law: Inverse relationship between volume and pressure

-Dalton's Law: Each gas exerts it's own independent pressure

-Henry's Law: Quality of gas dissolving in a liquid is proportion to:

1)Partial pressure of gas
2) Solubility

How does gas move through the respiratory membrane? What are the partial pressures of oxygen and carbon dioxide in oxygenated blood? In deoxygenated blood?
1) Diffusion
2) O2: 100-45 mmHg; CO2: 45-40mmHg
What factors influence the affinity of oxygen to hemoglobin? Explain how.
- pH decrease; Affinity decrease
- Heat increase; Affinity decrease
- BPG increase; Affinity decrease
- PCO2 increase; Affinity decrease
What makes up the respiratory membrane? Where is it found? What type of cell makes surfactant?
1) -Type I & II alveolar
-Epithelial Basement
Membrane
-Capillary Endothelial

2) Lungs

3) Type 2
In milliliters, what is the tidal volume? what percentage of that air actually reaches the capillaries.
-500mL
-70%
What factors affect the rate of gas exchange? Why is the air "thin" in the mountains?
1. a)Partial pressure difference b)membrane thickness c)surface area of gas exchange d) ventilation perfusion ratio

2. Air pressure is less up in the mountains, so the air there is dense
Explain the cardiac cycle including events of systole, diastole, and valve position.
Atrial: Atrium contracting, ventricle is relaxed; AV valve open,SL valve closed; blood fills up into the ventricle EDV=130mL

Ventricular: Atrium is relaxed; ventricle is contracting; SL valve are opened AV valve closed

Relaxation: All valves are closed for a moment
What is the pacemaker of the heart called? If it fails, what can compensate for it?
-SA node is the pacemaker
-AV node compensates if the pacemaker fails

What is the function of the small intestine? How is it adapted to preform that function?
-Responsible for breaking down food,,
-these three help break down food,
1) Duodenum
2) Jejunum
3) ilei
-when the stomach is full it tells the brain to slow down or stop. So it can process what's already in the intestines.
-Chemical breakdown use circular folds,villi, and microvilli (brush border): sucrase, lactase, and maltase
Explain what happens in the three phase of digestion. Include any chemicals and neurological competent.
1) Cephalic Phase
-Thoughts of food, etc
2) Gastric Phase (food in stomach)
-Stretch receptor, chemoreceptors-pH, gastric relaxes
3) Intestinal Phase (food in intestine)
-CCK: gallbladder, tells pancreas to release enzymes
-Secretin: stops gastric emptying, tells pancreas to release bicarbonate
** both: Stimulates pancreatic juices
List the enzyme that deal with carbohydrate. Where is each manufactured? What is their substrate?
Made by pancreas:
-Amylase ➡️ Starch
-Lipase ➡️ Lipid
-Trypsinogen + Enterokinase = Tsypsin
-Chymotrypsinogen
-Procarboxypeptidase + Trypsin
-Proaminopeptidase
Pepsin