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16 Cards in this Set

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P.N- what is Jaundice?
an excess bile pigments (billiverdin-green & b. rubin-yellow/orange) accumulate in the blood- it yellows the sclera, skin and nails
Altitude
(Factors affecting Erythropoiesis)
low atmospheric pressure @ high altitudes dec. Oxygen absorption
Pathology
(Factors affecting Erythropoiesis)
e.g., Blood loss, lung disease
B Complex Vitamins
(Factors affecting Erythropoiesis)
B12 & folic acid req. for DNA synthesis & producing Erythropoiesis
Minerals
(Factors affecting Erythropoiesis)
Fe is req. for hemoglobin synthesis
pregnancy
(Factors affecting Erythropoiesis)
blood vol. Inc, during pregnancy due to H2) retention but hematocrit decreases. Imbalance corrected by erythropoiesis.
Characteristics of Leukocytes (WBC's)
1. nucleated
2. capable of leaving circulatory system
3. 2x size of RBC in mammals
4. formed in red marrow
5. life span of WBC is 12hrs w/ exception of lymphocytes
6. comprise less than 1% of Pack cell volume
7. fight disease
8.Transported in circ. system
Types of WBC's
Classified based upon:
a. nuclear size and shape
b. size.
c. granulation of the cytoplasm
(Granulocytes)
Neutrophils (f)
F: phagocytize bacteria, fungi and some viruses
(Granulocytes)
Eosinophils (f)
f: moderate allergic reactions, fight parasitic worms (1-3% of WBC's)
(Granulocytes)
Basophils (f)
f: travels to damaged tissue and releases histamine and heparin (prevents clotting)
Heparin dilates capillaries & Inc. permeability allowing;
a)inc. blood flow to area
b)fluids to swell tissues (edema) reducing movement of pathogens through tissues.
(Agranulocytes-no cytoplasmic grains)
-Monocytes (f)
f; mature into macrophages that phagocytize bacteria, dead cells, and debris. (3-9% of WBC's)
(Agranulocytes-no cytoplasmic grains)
-Lymphocytes
Two major forms (25-33% of WBC's)
f: T CElls and B cells
T Cells (f):
directly attack; tumor cells, foreign cells, some microorganisms
B cells (function)
Produce antibodies (gamma globulin proteins) that attack; foreign cells and foreign proteins