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9 Cards in this Set
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Herpesvirus
Acyclovir (Zovirax), Valacyclovir (Valtrex), Famiciclovir (Famvir) |
TX for HSV1 and 2, VZV, EBV,
Does not cure, used to alleviate S/S Monitor I/O, encourage fluids, monitor BUN and creatine |
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Influenza
Oseltamicir (Tamiflu), Zanamivir (Relenza) Prophylaxis- Amentadine (Symmetrel), Rimantidine (Flumadine) |
Prophylactiv meds start 48 hours after exposure
Screen for hx of substance abuse/suicide, may increase mental disease |
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Hepatitis
Adefovir dipivoxil (Hepsera) Entecavir (Baraclude), Tenofovir (Viread), Lamivudine (Epivir HBV) |
Tx of chronic Hep B infections
SE: GI, fatigue, hepatoxicity Monitor ALT, AST, blood counts |
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Interferons:
Peginterferon alfa 2a (Pegasys) Antivirals Ribavirin (Copegus, Virazole, Rebetol, Ribasphere) |
Tx of Hep C
SE: fatigue, HA, malaise, anorexia, diarrhea, suprainfection, thrombocytopenia |
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Antiretrovirals (HIV infection)
Fusion and Intefrase inhibitors Raltegravir (Isentress), Maraviroc (Selzentryl), Enfuvirtide (Fuzeron) |
Combination therapy only
SE: abdomincal pain, fatigue, GI complaints, nuetropenia, thrombocytopenia, nephrotoxicity, cough, dizziness, pyrexia, rash, upper respiratory infections, hepatoxicity, increased risk for MI CX: CAD, monitor ALT, AST |
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Antiretrovirals (HIV infection)
Monitor? |
Monitor CD4+ Teell counts, and HIV RNA viral load with all antiretrovirals
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Antiretrovirals (HIV infection)
Protease inhibitors Saquinavir mesylate (invirase), Nelfimavir (Viracept), Iopinavir/Ritomavir (Kaletra) |
SubQ site reactions, resistance develops rapidly, administer with NRTI, St Johns Wort contraindicated (reduces efficacy)
SE: GI, diarrhea, anemia, leucopenia, lymphadenopathy, hemorrhagic colitis, pancreatitits |
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Antiretrovirals (HIV infection)
Nucleoside/Nucleotide Reserve Transcriptase Inhibitors (NRTIs) Zidovudine or AZT (Retrovir) |
SE: rash, malaise, GI, bone marrow supression, Nurtopenia, anemia, neurotoxicity
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Antiretrovirals (HIV infection)
Non Nucleoside Reserve Transcriptase Inhibitors (NNRTIs) Efavirenz (Sustiva), Delavidrine (Rescriptor) |
SE: rash, GI, paratesia, hepatoxicity, Stevens Johns Syndrome.
Monitor ALT, AST |