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10 Cards in this Set

  • Front
  • Back

Propulsive Uncontrolled Movement

occurs when mobility has deteriorated to cause patient to have quickened and shortened steps

Bradykinesia

difficulty performing intentional movements, slow and jerky

Akinesia

loss of movement

tremors

occur at rest, typically start in hand/ face

Dopaminergic Agent Adverse effects

Orthostatic Hypotension. Fall risk.

Drug interactions

Vitamin B6 decreases the effectiveness

Carbidopa and Levodopa

Drug of choice for Parkinsons


Levadopa will work in the CNS


Carbidopa reduces the metabolism of levadopa so more of administered levadopa reaches receptor site


restores dopaminergic actions



Anticholinergeric Agents

Oppose effects of acetylcholine


have a great affinity for receptor sites in CNS than peripheral


helps with tremors and drooling





Adverse Effects of Anticholinergic Agents (ABCDSS)

agitation

blurred vision


constipation


dry mouth


stasis of urine/ sweating

Adjunctive Agents

COMT inhibitors reduce destruction of dopamine in the peripheral tissues