Antimuscarinic & Ganglionic Drugs

Front 1

Atropine
-Class
-Therapeutic use
-Adverse effects

Back 1

-Antimuscarinic tertiary amine
-visceral hypermotility, excessive salivation, cardiovascular disorders, AchE OD, ophthalmology(* can last 3 days), preanesthetic medication
-atropine poisoning (100> in adults, but 5mg can be lethal in kids), symptoms appear 30-60min ingestion and can last 2-7 days, death due to respiratory failure

Front 2

Scopolamine
-Class
-Therapeutic use
-Adverse effects

Back 2

-Antimuscarinic tertiary amine
-motion sickness prevention/tx, ophthalmology, preanesthetic medication

Front 3

Homatropine
-Class
-Therapeutic use
-Adverse effects

Back 3

-Antimuscarinic tertiary amine
-Opthalmology

Front 4

Darifenacin (benztropine)
-Class
-Therapeutic use
-Adverse effects

Back 4

-Antimuscarinic tertiary amine, can only block M3
-neurogenic bladder, urinary urge incontinence

Front 5

Glycopyrrolate
-Class
-Therapeutic use
-Adverse effects

Back 5

-Antimuscarinic quaternary ammonium compound (also blocks nicotinic receptor), 1/2 life ~10hrs, doesn't enter CNS
-visceral hypermotility and spasms, cardiovascular disorders, preanesthetic medication

Front 6

Ipratropium
-Class
-Therapeutic use
-Adverse effects

Back 6

-Antimuscarinic quaternary ammonium compound (also blocks nicotinic receptor)-doesn't enter CNS
-Bronchospastic disorders: ONLY antimuscarinic drug used for bronchial asthma and COPD since it doesn't decrease bronchial secretions and mucociliary clearance

Front 7

Nicotine
-Class
-Therapeutic use
-Adverse effects

Back 7

-Ganglionic stimulant
-treatment of nicotine addiction

Front 8

Mecamylamine
-Class
-Therapeutic use
-Adverse effects

Back 8

-Ganglionic blocking, competitively blocks Nn, given orally and can enter CNS/BBB
-Some neurological dz like Tourette's, and therapy for nicotine and cocaine dependence