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8 Cards in this Set
- Front
- Back
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What are some common pitfalls in prescribing antibiotics ?
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prescribing for viruses or chronic colonization
overusing combination therapy using a drug beyond its scope using for persistent fever inadquate surgical therapy home IV therapy |
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Why is monotherapy preferred ?
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less potential for error
cost less ADR's (less suprainfections,less toxic and allergic reactions) |
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What are the indications for using combination therapy ?
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initial therapy for severe infection w/ unknown etiology
mixed infections to prevent resistance in TB decreased toxicity (able to reduce the dose of both meds) enhanced antibacterial action |
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What are two situations where combination therapy is useful in preventing resistance ?
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Aminoglycosides and penicillin
Rifampin and INH for TB |
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Why do we draw and monitor peak levels ?
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for efficacy purposes
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Why do we draw and monitor trough levels ?
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for toxicity...if the trough stays too high, it can be toxic
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When do you draw a trough ?
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at least 30 minutes before the dose
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When do you draw a peak ?
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2 hours after the dose
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