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48 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Moraxella catarrhalis
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TMP-SMZ.
What is the mechanism of resistance? |
1 decreased sensitivity of dihydropterate synthase or DHF reductase for drug (chromosomal mutation)
2 exogenous folate source |
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Neisseria gonorrhoeae
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Ceftriaxone, cefpodoxime
If the patient had a cephalosporin allergy, what would be an alternative? |
Spectinomycin
Aminoglycoside-like 50s initiation inhibitor, administered by IM injection |
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Neisseria meningiditis
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Penicillin G.
But uh OH! this patient has a beta-lactam sensitivity. What now? |
Administer chloramphenicol, despite risk of fatal aplastic anemia
Cephalosporin is also an option, but there is a slight chance of cross-reactivity. |
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E Coli, Klebsiella, Proteus
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Cephalosporin (1st or 2nd), TMP-SMZ.
But this patient has a beta-lactam sensitivity AND a sulfa allergy. What now? |
Quinolone or aminoglycoside
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Enterobacter, Citrobacter, Serratia
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TMP-SMZ, quinolone, carbapenem
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Shigella
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Quinolone
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Salmonella
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TMP-SMZ, quinolone, cephalosporin (3rd gen)
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Campylobacter jejuni
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Erythromycin or azithromycin
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Brucella sp
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Tetracycline
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H. Pylori
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bismuth + metronidazole + tetracycline or amoxicillin
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Vibrio sp
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Tetracycline
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Pseudomonas aeruginosa
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Anti-pseudomonal penicillin + aminoglycoside
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Burkholderia cepecia (Pseudomonas cepacia)
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TMP-SMZ
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Stenotrophomonas maltophilia (Xanthomonas maltophilia)
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TMP-SMZ
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Legionella sp
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Azithromycin + rifampin or quinolone + rifampin
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Streptococcus pneumonae
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Penicillin
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Streptococcus pyogenes (Group A)
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Penicillin, clindamycin
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Streptococcus agalactiae
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Penicillin (+aminoglycoside?)
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Viridans streptococci
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Penicillin
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Beta-lactamase negative Stapholococcus aureus
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Penicillin
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Beta-lactamase positive Staphylococcus aureus
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Penicillinase-resistant penicillin
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Methicillin resistant-Staph aureus
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Vancomycin
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Enterococcus sp
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Penicillin +/- Aminocglycoside
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Bacillus sp (non-anthracis)
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Vancomycin
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Listeria sp
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Ampicillin (+/- aminoglycoside)
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Nocardia sp
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Sulfadiazine, TMP-SMZ
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Gram positive anaerobes (clostridia, peptococcus, actinomyces, peptostreptococcus)
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penicillin, clindamycin
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Clostridium difficile
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Metronidazole
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Bacteroides fragilis
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Metronidazole
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Fusobacterium, Prevotella, Porphyromonas
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Metronidazole, clindamycin, penicillin
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Mycobacterium tuberculosis
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Isoniazid + rifampin + ethambutol + pyrazinamide
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Mycobacterium leprae, multibacillary and paucibacillary
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Multibacillary: dapsone +rifampin + clofazimine
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Mycoplasma pneumoniae
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Tetracycline, erythromycin
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Chlamydia trachomatis
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Tetracycline, azithromycin
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Chlamydia pneumoniae
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Tetracycline, erythromycin
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Chlamydia psittaci
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Tetracycline
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Borrelia recurrentis
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Doxycycline
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Borrelia burdorferi
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Doxycyline, amoxicillin
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Leptospira sp
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Penicillin
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Treponema sp
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Penicillin
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Aspergillus sp
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Voriconazole
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Blastomyces sp
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Amphotericin B
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Candida sp
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Amphotericin B, capsofungin
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Cryptococcus
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Amphotericin B +/- flucytosine
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Coccidiodes immitis
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Amphotericin B
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Histoplasma capsulatum
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Amphotericin B
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Mucoraceae (Rhizopus, Absidia)
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Amphotericin B
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Sporothrix schenkii
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Amphotericin B
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