Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
32 Cards in this Set
- Front
- Back
|
Penicillins
Mechainsm Resistance Pharacokinetics Adverse RXNS |
bind PBP
Beta-Lactamase or mutate PBP Short half life, kidney excrete with no metabolism Hypersensitivity with immediate anaphylaxis and uticaria; delayed days to weeks with rash, fever, serum sickness. |
|
|
Natural penicillins
Resistance Types Sucept |
MRSA
Procaine PenG: IM, lasts 1 - 4 d, longer with probenicid banzathine Pen G: IM, weeks Pen V: oral, acid stable Strep pyogenes, penomo, n> Meningitis, Clostridium |
|
|
Aminopenicillins
Resist How Made Types Sucepts |
MRSA
semi0synthetic Amipicillin, 4x/d, idiosyncratic rash esp with mononucl and allopurinol amoxicillin:most common abiotic, also has same idiosyncratic rxn, 2 - 3 /d, and higher dose for penicillin resit pneumococcus Haemo influenza, enterococcus, strep pyogenes, pneumo, proteus gram - |
|
|
Extended spectrum Pseudomonal penicillins
Drugs Adverse Uses Resist |
pierpacillin pipracil with tazobactam zosyn, excrete in biliary tract
high dose gives Na overload and thrombocytopenia combine with aminoglycosides for gram - bacteria MRSA |
|
|
B-lactamase inhibitor penicillin combos
Name them Mechanism |
Augmentin with claugenlanic acid and amoxicillin for diabetic foot and bites
Unasyn with sulbactam and ampicillin Zosyn with tazobactam and piperacillin is most used IV in hospitals for all grams and anaerobics Same adverse rxns as penicillins |
|
|
Penicillinase resistant penicillins
|
Methicillin for MRSA
Nafcillin can cause phlebitis, 4 - 6 / d, Dicoxacillin give oral |
|
|
Cephalosporins
Origin Mech Bact resistance Pharmacokinetics Adverse Rxns Describe the different generations and their uses. |
.
|
|
|
Monobactams
Does it have the same penicillin rxns? What is suscept? What is resistant? |
.
|
|
|
Carbapenems
Describe the spectrum. Name some of the drugs and how they are used. What are these drugs used for? What are some bad reactions? |
.,
|
|
|
Penicillins
Mechainsm Resistance Pharacokinetics Adverse RXNS |
bind PBP
Beta-Lactamase or mutate PBP Short half life, kidney excrete with no metabolism Hypersensitivity with immediate anaphylaxis and uticaria; delayed days to weeks with rash, fever, serum sickness. |
|
|
Natural penicillins
Resistance Types Sucept |
MRSA
Procaine PenG: IM, lasts 1 - 4 d, longer with probenicid banzathine Pen G: IM, weeks Pen V: oral, acid stable Strep pyogenes, penomo, n> Meningitis, Clostridium |
|
|
Aminopenicillins
Resist How Made Types Sucepts |
MRSA
semi0synthetic Amipicillin, 4x/d, idiosyncratic rash esp with mononucl and allopurinol amoxicillin:most common abiotic, also has same idiosyncratic rxn, 2 - 3 /d, and higher dose for penicillin resit pneumococcus Haemo influenza, enterococcus, strep pyogenes, pneumo, proteus gram - |
|
|
Extended spectrum Pseudomonal penicillins
Drugs Adverse Uses Resist |
pierpacillin pipracil with tazobactam zosyn, excrete in biliary tract
high dose gives Na overload and thrombocytopenia combine with aminoglycosides for gram - bacteria MRSA |
|
|
B-lactamase inhibitor penicillin combos
Name them Mechanism |
Augmentin with claugenlanic acid and amoxicillin for diabetic foot and bites
Unasyn with sulbactam and ampicillin Zosyn with tazobactam and piperacillin is most used IV in hospitals for all grams and anaerobics Same adverse rxns as penicillins |
|
|
Penicillinase resistant penicillins
|
Methicillin for MRSA
Nafcillin can cause phlebitis, 4 - 6 / d, Dicoxacillin give oral |
|
|
Cephalosporins
Origin Mech Bact resistance Pharmacokinetics Adverse Rxns Describe the different generations and their uses. |
.
|
|
|
Monobactams
Does it have the same penicillin rxns? What is suscept? What is resistant? |
.
|
|
|
Carbapenems
Describe the spectrum. Name some of the drugs and how they are used. What are these drugs used for? What are some bad reactions? |
.,
|
|
|
Bacitracin
What is it used for? How is it given? |
.
|
|
|
Daptomycin, cubicin
How is it given? What is the mech? What is it used for? |
.
|
|
|
Vancomycin
How does it work? What is suscept? How is it given? Describe the pharmacokinetics. What are some adverse rxns? What is it used for? |
.
|
|
|
Macrolides
Mech? Suscept? Uses? Drug examples. What are some negative interactions for the drugs? |
.
|
|
|
Ketolides, Telithromycin
Mech? Interactions. Suscept |
.
|
|
|
Tetracyclines
Mech. What is suscept? Adverse rxns and interactions. Uses. Drug examples and uses |
.
|
|
|
Quinupristin, dalfopristin, synercid
Mech Suscept Uses How to give. Adverse reactions and interactions |
.
|
|
|
Aminoglycosides
Mech Sucept Resistant Uses Pharacokinetics Adverse Rxns Drugs and uses |
.
|
|
|
Clindamycin, cleocin
Mech Suscept Uses Pharmacokinetics Adverse Rxns |
.
|
|
|
Mupirocin, Bactroban
What is it used for? |
.
|
|
|
Fluoroquinolones
Mech Sucept Uses Pharacokinetics. Adverse rxns Drug interactions Describe the different generations of drugs |
.
|
|
|
Trimethoprim, sulfamethoxazole, bactrim
Mech Suscept uses Pharacokinetics Adverse Rxns Drug interactions |
.
|
|
|
Nitrofurantoin
Uses reactions |
.
|
|
|
Metronidazol flagyl
uses how to give cross reactive with? |
.
|
