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34 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What blocks peptidoglycan synthesis?
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Bacitracin, vancomycin, cycloserine
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What blocks mRNA synthesis?
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Rifampin
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Name the bactericidal antibiotics.
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Cephalosporins, Aminoglycosides, PCN, Vancomycin, Fluoroquinolones, Metronidazole
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CAP Villinous Fuckin Microbes:
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What antibiotic causes interstitial nephritis?
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methicillin
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What are the main SE of PCN?
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hemolytic anemia, hypersensitivity
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What are the 4th generation PCNs? What does it treat?
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Ticarcillin, Carbenicillin, Piperacillin - pseudomonas and GNR
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Ticking car pipe bomb
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What should you use w/ 3rd and 4th generation PCNs?
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clavulinic acid.
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What causes pseudomembranous colitis?
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clindamycin and Ampicillin
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What drug is given w/ imipenem? Why?
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Cilastin- Renal dehydroepeptiase I inhibitor to prevent metabolism.
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What are the side effects of cilastin/imipenem and meropenem?
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carbapenem SE include skin rash, seizures, and stomach upset
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3S
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What are the side effects of vancomycin?
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nephrotoxicity, ototoxicity, thrombophlebitis, red man syndrome
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NOT Vance!
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What are the side effects of amnoglycosides?
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nephrotoxicity, ototoxicity, teratogen
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NOT!
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What suffix do aminoglycosides have?
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mycin except amikacin
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What antibiotic cannot be give w/ divalent cations (in milk, anatacids, Fe)?
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tetracyclines
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What do tetracycles treat?
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Vibrio, acne, chlamydia, urealytica, ureaplasma, mycoplasma pneumoniae, tularemia, borrelia burgdoferri, rickettsiae
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Vacuum The BedRoom
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Which two antibiotics are contraindicated in pregnancy?
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metronidazole, chloramphenicol, aminoglycosides, tetrcyclines
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MCAT
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Side affect of sulfonamides (SMX)?
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G6PD hemolysis, displacement of other drugs from albumin, nephrotoxicity, kernicterus in infants and hypersensitivity.
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Good Drugs Never Kills Humans
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Side effects of TMP?
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megaloblastic anmia, leukopenia, granulocytopenia
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TMP Treats Marrow Poorly
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What do polymyxins treat?
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resistant gram negatives
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What does metronidazole treat?
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giardia, entamoeba, trichomonas, giardia, anaerobes, H pylori (w/ bismuth and amoxicillin)
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GET Gap on the Metro
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What does fluoroquinolones treat?
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gram negative rods of urinary and GI tracts
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What are the side effects of fluoroquinolones?
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tendonitis, tendon rupture, cartilage damage
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Lones hurt your bones
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What are the side effects of INH?
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neurotox, hepatotox, G6PD hemolysis, SLE-like syndrome: use Vit B6 to prevent neurotox.
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Injures nerves and hepatocytes (INH)
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What are the 4Rs of rifampin?
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RNA polymerase inhibitor, rapid resistance if used alone, Revs up P-450, Red/orange body fluids
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How do you prophylax gonorrhea?
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ceftriaxone
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How do you prophylax syphilis?
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benzathine penicillin G
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How do you prophylax meningococcal infection
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TMP-SMX
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How do you prophylax for endocarditis w/ surgical or dental procedures?
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PCN
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What are the SE of Amp?
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shaking (chills/fever), hypotension, anemia, kidney tox (nephrotoxicity), arrhythmias
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SHAKA
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What does fluconazole treat?
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cryptococcal meningitis in AIDS pts
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Think "flu" is in the head so it crosses BBB.
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How do you treat aspergillosis?
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caspfungin
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What Ab inhibits fungal squalene epoxidase?
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terbinafine
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What does terbinafine treat?
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dermatophytoses
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to be FINE you need to have nice skin
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What is the mechanism of amantidine and rimantidine? Which is safer?
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blocks viral uncoating, inhibits dopamine release from nerves. rimantidine is safer cuz it doesn't cross BBB
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think "a man to dine" takes off his coat
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