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34 Cards in this Set

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  • Back
  • 3rd side (hint)
What blocks peptidoglycan synthesis?
Bacitracin, vancomycin, cycloserine
What blocks mRNA synthesis?
Name the bactericidal antibiotics.
Cephalosporins, Aminoglycosides, PCN, Vancomycin, Fluoroquinolones, Metronidazole
CAP Villinous Fuckin Microbes:
What antibiotic causes interstitial nephritis?
What are the main SE of PCN?
hemolytic anemia, hypersensitivity
What are the 4th generation PCNs? What does it treat?
Ticarcillin, Carbenicillin, Piperacillin - pseudomonas and GNR
Ticking car pipe bomb
What should you use w/ 3rd and 4th generation PCNs?
clavulinic acid.
What causes pseudomembranous colitis?
clindamycin and Ampicillin
What drug is given w/ imipenem? Why?
Cilastin- Renal dehydroepeptiase I inhibitor to prevent metabolism.
What are the side effects of cilastin/imipenem and meropenem?
carbapenem SE include skin rash, seizures, and stomach upset
What are the side effects of vancomycin?
nephrotoxicity, ototoxicity, thrombophlebitis, red man syndrome
NOT Vance!
What are the side effects of amnoglycosides?
nephrotoxicity, ototoxicity, teratogen
What suffix do aminoglycosides have?
mycin except amikacin
What antibiotic cannot be give w/ divalent cations (in milk, anatacids, Fe)?
What do tetracycles treat?
Vibrio, acne, chlamydia, urealytica, ureaplasma, mycoplasma pneumoniae, tularemia, borrelia burgdoferri, rickettsiae
Vacuum The BedRoom
Which two antibiotics are contraindicated in pregnancy?
metronidazole, chloramphenicol, aminoglycosides, tetrcyclines
Side affect of sulfonamides (SMX)?
G6PD hemolysis, displacement of other drugs from albumin, nephrotoxicity, kernicterus in infants and hypersensitivity.
Good Drugs Never Kills Humans
Side effects of TMP?
megaloblastic anmia, leukopenia, granulocytopenia
TMP Treats Marrow Poorly
What do polymyxins treat?
resistant gram negatives
What does metronidazole treat?
giardia, entamoeba, trichomonas, giardia, anaerobes, H pylori (w/ bismuth and amoxicillin)
GET Gap on the Metro
What does fluoroquinolones treat?
gram negative rods of urinary and GI tracts
What are the side effects of fluoroquinolones?
tendonitis, tendon rupture, cartilage damage
Lones hurt your bones
What are the side effects of INH?
neurotox, hepatotox, G6PD hemolysis, SLE-like syndrome: use Vit B6 to prevent neurotox.
Injures nerves and hepatocytes (INH)
What are the 4Rs of rifampin?
RNA polymerase inhibitor, rapid resistance if used alone, Revs up P-450, Red/orange body fluids
How do you prophylax gonorrhea?
How do you prophylax syphilis?
benzathine penicillin G
How do you prophylax meningococcal infection
How do you prophylax for endocarditis w/ surgical or dental procedures?
What are the SE of Amp?
shaking (chills/fever), hypotension, anemia, kidney tox (nephrotoxicity), arrhythmias
What does fluconazole treat?
cryptococcal meningitis in AIDS pts
Think "flu" is in the head so it crosses BBB.
How do you treat aspergillosis?
What Ab inhibits fungal squalene epoxidase?
What does terbinafine treat?
to be FINE you need to have nice skin
What is the mechanism of amantidine and rimantidine? Which is safer?
blocks viral uncoating, inhibits dopamine release from nerves. rimantidine is safer cuz it doesn't cross BBB
think "a man to dine" takes off his coat