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7 Cards in this Set

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Classification of Anibiotics are based on __1___ and __2__ __ __2____.

4 Primary Classes are:
1. site
2. mechanism of action

1. Cell wall synthesis Inhibitors (Penicillin)

2. Protein Synthesis Inhibitors (Tetracycline)

3. Metabolic & nuclei acid inhibitors (Sulfa)

4. Cell membrane inhibitors (Ketoconazole)
Bactericidal: Drugs that __1__ the oragnism.

*example is ___2____
*drugs perferred mechanism of action
*__3__ or ___3__ something necessary for microbial survial
1. KILL
2. Penicillen
3. Inhibit or inactivate
Selection of Agents

*Determined by __1__ activity

*__2__ therapy use in routine
infections and initially in
severe infections.

*Drugs of Choice
*Many __3__
*__4___
1. Antimicrobial

2. Empiric

3. References

4. Experience
Concentration dependent drugs:

Examples of 2 types
Higher the concentration the more effective

1. fluroquinolone
2. aminoglycosie
Combination Therapy

*Often used in _1_
infections or _2_ to treat
organisms
i.e. M___ 3
P. ___ 4

*Used in _5_ infections
i.e. _6__ wounds or surgery

*For _7_ of resistance in
certain diseases
i.e. _ _ 8
1. Severe
2. Difficult
3. Meningitis
4. Aeruginosa
5. Mixed
6. GI
7. Prevention
8. TB
Penicillnase Resistant Agents

*N, M, D

*Used agains P-ase _4__ _5__
infections
*not useful vs other
p-ase resistant bact.
*Endocarditis,
Osteomylitis &
skin/soft tissue infec

*Staph resistant to these
are called __6___
1. Nafcillin
2. Methicillin
3. Dicloxacillin
4. Resistant
5. Staphylococcal
6. MRSA
Nitrofurantoin, Macrodantin,
Macrobid

*U T anti__ 1

*Use is ONLY in _ _ _ 2

*_3_ incidence of _4_

* _ _ upset is primary limiting factor
1. Urinary Tract antiseptic
2. UTI
3. Low
4. Resistance
5. GI