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13 Cards in this Set

  • Front
  • Back

Narrow spectrum

Antibiotic only affects a few organisms

Broad Spectrum

Large range of organisms affected



Example: some drugs combat both gram + and gram - bacteria

Bacteriocidal

Kill microbes directly

Bacterostatic

Prevent microbial growth (most bacteria)

Semisynthetic Penicillins

Example: Amoxicillin, Ampicillin

Polypeptide Antibiotics

Example: Bacitratin, Vancomycin


Nucleotide analogs

drugs that mimic nucleotides which prevents viral replication

Enzyme Inhibitors

Block viral enzymes, like neuraminidase in influenza



Example of drug: Acyclovir

Interferons

Proteins that are produced by cells infected with a virus. Cause uninfected cells to produce antiviral proteins.



Example of Drug: Tamiflu --> blocks enzyme

Broth dilution Test

Microdilution plates are used with many tiny wells with varying concentrations of antibiotics to determine the MIC

Blocking Entry

Some bacteria alter the structures of porins, which no longer allow entry of the antibiotics

Synergism

When two or more antibiotics are more effective when taken together

Antagonism

Antibiotics taken in tandem actually are less effective than when taken alone