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50 Cards in this Set

  • Front
  • Back
Calcium chelator
Tetracycline
Brown teeth
Tetracycline
Gray-baby syndrome
Chloramphenicol
Oto- and nephrotoxicity
Vancomycin, aminoglycosides
Optic neuritis
Ethambutol
Polyarthralgia
Pyrazinamide
Induces cytochrome P450
Rifampin
Red-man syndrome
Vancomycin
Pseudomembranous colitis
Clindamycin
Kernicterus
Sulfonamides
Megaloblastic anemia (supplement with vitamin B6)
Trimethoprim-sulfamethoxazole
Cartilage damage, tendonitis
Fluoroquinolones
Orange bodily fluids
Rifampin
Fast vs. slow acetylators
Isoniazid
Infusion-related toxicity
Amphotericin B
D-Ala-D-Ala
Vancomycin
PBP3
Aztreonam
Blocks peptidyltransferase
Chloramphenicol
Blocks peptide bond formation
Clindamycin
Blocks ribosomal translocation by preventing exit of tRNA
Macrolides
Inhibits initiation complex, causes mRNA misreading, blocks translocation
Aminoglycosides
Blocks tRNA binding to ribosome
Tetracycline
Bactericidal for H. flu, S. pneumo, N. meningitidis
Chloramphenicol
Blocks initiation step of protein synthesis
Linezolid
PABA analogue
Sulfonamides
Prevents synthesis of dihydrofolic acid
Sulfonamides
Inhibits dihydropteroate synthetase
Sulfonamides
Prevents synthesis of tetrahydrofolic acid
Trimethoprim
Inhibits dihydrofolate reductase
Trimethoprim
Resistance is due to rRNA methylation
Clindamycin, macrolides
DNA gyrase, topoisomerase IV
Fluoroquinolones
RNA polymerase
Rifampin
Inhibits mycolic acid synthesis
Isoniazid
Inhibits arabinogalactan synthesis
Ethambutol
Inhibits microtubule function
Griseofulvin
Inhibits beta(1,3)D-glucan synthetase
Caspofungin
Binds ergosterol
Amphotericin B, nystatin
Inhibits lanosterol demethylation by cytochrome P450
Azoles
Inhibits thymidylate synthase
Flucytosine
Used to treat cryptococcal meningitis
Flucytosine
Used for meningococcal prophylaxis
Rifampin
Used to treat Pseudomonas infection in CF patients
Fluoroquinolones
Used to treat nocardiosis
Sulfonamides
Used to treat VRE, MRSA, PRSP
Linezolid
Used to treat C. perfringens and B. fragilis
Clindamycin
Used to treat Mycoplasma pneumoniae
Tetracycline
Used to treat chlamydia
Tetracycline
Used to treat Legionella
Macrolides
Used to treat gonorrhea
Ceftriaxone
Used to treat H. flu meningitis
Chloramphenicol