11-Antimicrobial Drugs

Front 1

The findings of the antibacterial properties of penicillin notatum were first published by

Back 1

Fleming

Front 2

Prontosil, a dye, first used as an antibiotic by

Back 2

Domagk

Front 3

All of the following are General metabolic or structural targets for antimicrobial drugs except

Back 3

Lipid synthesis inhibition

Front 4

Which of the following is not a common characteristic used in the selection of an antimicrobial drug?

Back 4

Ability to administer intravenously or penetration of the blood-brain barrier

Front 5

The term bacteriostatic means that bacteria

Back 5

No longer can multiply

Front 6

Drugs that are effective against gram-positive and gram-negative bacteria, but not all of them, are__________ actively drugs

Back 6

Medium Spectrum

Front 7

Which of the following is not a test to determine the efficacy of an antimicrobial agent against a specific organism

Back 7

Polymerase chain reaction

Front 8

When two antibiotics are given together to increase the therapeutic effect, the phenomenon is referred to as

Back 8

Synergism

Front 9

Antimicrobial drugs that adversely affect the red bone marrow are referred to as

Back 9

Hemotoxic

Front 10

All of the following are mechanisms of resistance used by microbes except

Back 10

Changing ribosome composition

Front 11

Which of the following is a synthetic antimicrobial drugs?

Back 11

Quinolone

Front 12

Cephalosporins have____________ generations of developed agents

Back 12

Five

Front 13

Which of the following antimicrobial is effective against Mycobacteria?

Back 13

Rifampin

Front 14

Which of the following is an antiviral agent

Back 14

Amentadine

Front 15

Which of the following drug is effective against Candida albicans

Back 15

Echinocandins

Front 16

A drug that kills pathogenic bacteria is referred to as

Back 16

Microbicidal

Front 17

Most agents that inhibit protein synthesis involve disrupting the process of

Back 17

Translation

Front 18

An ideal antimicrobial drug will kill harmful microbes without significant damage to the host. This principal is referred to as

Back 18

Selective toxicity

Front 19

Another term for the effectiveness of a drug against a microbe is also referred to

Back 19

Efficacy

Front 20

An order for an antimicrobial drug to be able to cross the blood-brain barrier it must be__________ soluble

Back 20

Lipid

Front 21

Resistance to only one type of drug may allow resistance to a similar drug; this process is called

Back 21

Cross resistance

Front 22

The range of pathogen type that a given drug is effective against is referred to as the drug's

Back 22

Spectrum of activity

Front 23

In the MIC method of determining antibiotic Effectiveness, the lowest concentration containing no living organisms is called the

Back 23

Minimal bacterial concentration

Front 24

The zone of inhibition is the result of the __________method

Back 24

Disk diffusion and Kirby Bauer

Front 25

The assessment of a drug to determine its benefits versus the risks is called the

Back 25

Therapeutic index

Front 26

Erythromycin

Back 26

Sansac

Front 27

Clindamycin

Back 27

Dalacin

Front 28

Rifampan

Back 28

Rofact

Front 29

Isoniazide

Back 29

Nydrazid

Front 30

Ethambutol

Back 30

Etibi

Front 31

Describe the five basic mechanism of action that are targeted by antimicrobial drugs

Back 31

Inhibition of cell wall synthesis, inhibition of protein synthesis, inhibition of nucleic acid synthesis, inhibition of metabolic pathways, disruption of plasma membrane