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12 Cards in this Set
- Front
- Back
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Who developed the "magic bullet"?
When? What number proved successful? |
Paul Ehrlich. early 1900's.
#606 cured Trypanosomal infections |
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What is the magic bullet now referred to as?
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Selective Toxicity.
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Therapeutic index = ?
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minimum toxic dose / minimum effective dose
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A low ratio for a therapeutic index would be _______ toxic to a patient.
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More toxic.
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What is a broad spectrum antibiotic?
What are some popular examples? (3) |
Broad spectrum antibiotics are effective against many types of bacteria.
ampicillin, tetracycline, streptomycin |
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Who discovered Penicillin?
Penicillin is _____ spectrum? |
Fleming 1928.
Narrow spectrum. |
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Who were the first to perform clinical trials for penicillin?
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Florey and Chain 1940.
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What are the three categories of antibiotic resistance mechanisms?
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1. Resistance Genes
2. Mutations 3. Multiple resistance |
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Indinavir inhibits ______ (HIV)
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Protease
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Zanamivir inhibits ______ (influenza)
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Attachment
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Amantadine inhibits _______(influenza)
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uncoating
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Interferons prevent the spread of what?
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Viruses
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