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21 Cards in this Set

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Aminoglycosides MOA
Inhibit bacterial RNA synthesis - bactericidal
Aminoglycosides adverse events
Nephrotoxicity - increase in BUN and SCr
Ototoxicity
Aminoglycoside Examples
Amikacin, Gentamicin, Neomycin, streptomycin
Penicillins MOA
Inhibit cell wall synthesis by binding PBPs - bactericidal
Penicillin Adverse events
GI, Allergic, Hypokalemia
Cephalosporins MOA
Inhibit mucopeptide synthesis in bacterial cell wall
Cephalosporins Adverse Drug events
Hypersensitivity, GI, Seizures, C. Diff colitis
Fluoroquinolones MOA
inhibit bacterial DNA topoisomerase
Fluoroquinolones Adverse drug events
GI, CNS, QT prolongation
Fluoroquinolones examples
Ciprofloxacin, Levofloxacin, Oflaxacin
Fluoroquinolones Counseling
Don't take antacints, calcium, magnesium, iron at least 2 hour after each dose
Macrolides MOA
Inhibit RNA synthesis
Macrolides ADEs
GI, QT prolongation, ototoxicity
Macrolides examples
Azithromycin, clarithromycin, erythromycin
Tetracyclines Spectrum of Activity
Respiratory infections, genital infections
Tetracyclines counseling
Administer with food
Tetracyclines ADEs
Photosensitivity reactions
Contraindicated in pregnancy, and children
Hepatotoxic
GI intolerance
Antacids decrease GI absorption
Tetracyclines examples
Doxycycline, Minocycline, Tetraycycline
Sulfonamides MOA
Interfere with folic acid synthesis
Sulfonamides ADEs
rash, urticaria
Sulfonamides examples
Sulfamethizole, sulfamethoxazole