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10 Cards in this Set
- Front
- Back
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What is Hypertension?
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When the systolic exceeds 140mmhg and diastolic exceeds 90mmhg
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What are the therapeutic objectives for Hypertension?
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Prevention of organ damage
Reduction of mortality Easiest to do this by lowering BP rather than looking at individual cases |
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What can the patient do prior to drug treatment to attempt to lower BP?
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Lower body weight
reduce Nacl |
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What are the drugs of first choice in hypertension?
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Diuretics
B-Blockers |
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What is the first option of drug in HT?
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Thiazide Diuretics
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What if the first option doesn't work, what can you add?
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B-Blocker or ACE Inhibitor, AT1 Antagonist or Ca2+ Blocker (Dependant on patient issues)
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How do ACE inhibitors assist in lowering BP?
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Reduce ANGII = reduced peripheral vascular resistance and reduced BP.
May induce Dry cough, Impair renal function or hyperkalemia (then At1 antagonist) |
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Who should not have B-Blockers
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Those with lung disease, COPD as can impair pulmonary function
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Why are Ca2+ Blockers good and is there a risk?
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Dihydropyridines - Long Half Life - beneficial as short Half life drugs rapidly lower BP and elicit reflex Tachy.
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Is mono therapy the best or combined therapy?
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Not really combined is better.
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