Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
Fluoxetine
Sertraline Paroxetine Fluvoxamine Citalopram Escitalopram |
SSRIs
Inhibit 5HT reuptake and some NE/DA reuptake Don't have risk of cardiac arrythmia in OD like TCAs Side effects are Nausea, Sexual dysfunction and Fatigue |
|
|
Venlafaxine
Desvenlafaxine Duloxetine |
SNRIs
Inhibit 5HT and NE reuptake Same side effects as SSRI except for increased BP |
|
|
Mirtazepine
|
Atypical Antidepressant
Antagonist at a2 and 5HT receptors Side effects are sedation and weight gain |
|
|
Buproprion
|
Atypical Antidepressant
NDRI: Inhibits uptake of NE and DA Side effects are agitation, insomnia, weightloss and low seizure threshold |
|
|
Nefazodone and Trazodone
|
SARIs
5HT receptor antagonist and 5HT reuptake inhibitor Side effects are sedation, orthostatic hypotension and priapism |
|
|
Alpha 1 subunit on GABA channel
|
Hypnotic, Amnestic
|
|
|
Alpha 2 & 3 subunit on GABA channel
|
Anxiolytic
|
|
|
Alpha 5 subunit on GABA
|
Tolerance
|
|
|
1st Line therapy for anxiety disorders
|
SSRIs or SNRIs
Ineffective in acute panic Increased anxiety on initiation |
|
|
2nd line therapy for anxiety disorders
|
Buspirone
5HT1 agonist Faster onset than AD but slower than BZD Non sedative and no potential for abuse |
|
|
1st line therapy for anxiety disorder and acute panic attacks
|
SSRI + BZD
(SSRI negates the rebound anxiety of BZDs) |
|
|
Short acting BZDs for parenteral or preanesthetic procedure
|
Midalozam (Versed)
Lorazepam (Ativan) |
|
|
Flumenazil
|
BZD binding site antagonist to reverse overdose or therapeutic effect
|
|
|
Z drugs for insomnia
|
Alpha 1 selective and act at BZD site
No REM rebound like BZDs No disruption of sleep architecture |
|
|
Zolpidem
|
Z drug for insomnia
|
|
|
Zaleplon
|
Z drug
Short half life Can be given in middle of night to go back to sleep |
|
|
Eszoplicone
|
Z drug approved for chronic use
|
|
|
Ramelteon
|
Treats circadian desynchrony
|
