Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

6 Cards in this Set

  • Front
  • Back
Activates antithrombin III, decreases thrombin & factor Xa.

Intrinsic pathway inhibitor, increases PTT more than PT.

Short half-life. Does not cross placenta.

Antidote = protamine sulfate
Inhibits synthesis & gamma-carboxylation of vit K dependent factors (II, VII, IX, X, prot C, prot S).

Crosses placenta (teratogen).

Inhibits extrinsic pathway, increases PT.

Antidote = vitamin K, fresh frozen plasma
Irreversibly inhibits COX-1 and COX-2.

Increased bleeding time. No change to PT, PTT.

SE: ulcers, bleeding, hyperventilation, Reye's syndrome, tinnitus (CN8)
Clopidogrel, Ticlopidine
Inhibits platelet aggregation. Irreversibly blocks ADP receptors, blocks GP IIb/IIIa expression.

SE: ticlopidine = neutropenia
Inhibits platelet aggregation, antibody to GP IIb/IIIa receptors.

SE: thrombocytopenia
tPA, urokinase, streptokinase, anistreplase
Thrombolytics, aid conversion of plasminogen to plasmin and cleaves thrombin/fibrin clots.

Antidote = aminocaproic acid (fibrinolysis inhibitor)