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7 Cards in this Set
- Front
- Back
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Where is specificity of antibodies determined?
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Variability 2
where antigen binds |
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Antigen binding sites of Ig
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CDR of both light and dark chain combined
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Instructive theory
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Cells respond to antigens and make antibodies accordingly
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Selective theory
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Cells
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B cells in bone marrow
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Lymphoid stem cell --> immature b cell --> mature B cell
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B cells in peripheral system
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After antigen stimulation --> plasma cell and memory B cell
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germ line DNA
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DNA which is passed down through the gamete before somatic recombination
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