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11 Cards in this Set
- Front
- Back
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What bacterial species from soil are made into antibiotics?
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Streptomyces spp. and Bacillus Spp.
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What fungi species from soil are made into antibiotics?
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Penicillium Spp. and Cephalorsporin spp.
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Which one supplies more thn 50% of the current antibiotics?
Streptomyces Bacillus Penicilluim Cephalosporin |
streptomyces
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What is a narrow spectrum antibiotic?
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An antibiotic that targets a limited number of species.
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What is a broad spectrum antibiotic?
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An antibiotic that target a broad range of species.
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What is special about the mycobacteria?
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The wax like mycolic acid that replaces LPS. This resists penetration by antibiotics.
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Explian Rickettsia and Chlamydia.
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They are obligatory intracellular parasites, gram (-) enveloped cells. Chlamydia spp. have no peptidoglycan, and rickettsia spp. are transmitted by insects.
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What are the advantages of narrow spectrum antibiotics?
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The antibiotic is more specific so it can target the pathogen. Also normal microbiota does not take as big a hit because it is so specific.
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What are the disadvantages or narrow spectrum antibiotics?
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The disadvantages are that it is only effective against a limited species, and can't have widespread use.
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What are superinfections?
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These are infections that only occur because of antibiotic use. the normal flora of the body is damaged so oppurtunistic pathogens are free to infect the body.
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What are the prime modes of antibiotic action?
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1) inhibition of cell wall synthesis
2) inhibition of protein synthesis 3) disruption of plasma membrane 4) inhibition of nucleic acid synthesis 5) inhibition of metabolite synthsis |
