Antibiotics

Front 1

Chemical substance produce by microorganism

Back 1

Antibiotics

Front 2

Limited number of pathogen

Back 2

Narrow spectrum

Front 3

Destroy different kinds of organism

Back 3

Broad spectrum

Front 4

Produced by bacteria

Back 4

Natural drugs

Front 5

Bacillus subtilis

Back 5

Bacitracin

Front 6

Bacillus polymyxa

Back 6

Polymyxin

Front 7

Streptomyces nodosus

Back 7

Amphotericin B

Front 8

Streptomyces venezuelae

Back 8

Chloramphenicol

Front 9

Streptomyces erythreus

Back 9

Erythromycin

Front 10

Streptomyces noursei

Back 10

Nystatin

Front 11

Streptomyces fradiae

Back 11

Neomycin

Front 12

Microspora purpurea

Back 12

Gentamycin

Front 13

Cephalosporium

Back 13

Cephalosporin

Front 14

Penicillium notatum

Back 14

Penicillin

Front 15

Modified natural drugs

Back 15

Semi- synthetic drugs

Front 16

Chemically produced drug

Back 16

Synthetic drug

Front 17

Chloramphenicol

Back 17

Synthetic drug

Front 18

Ampicillin

Back 18

Semi synthetic drugs

Front 19

Isoniazid

Back 19

Synthetic drugs

Front 20

Trimetophrim

Back 20

Syntehtic drugs

Front 21

Kill organism: life threatening infection

Back 21

Bactericidal

Front 22

Inhibit bacterial growth nut niy actually kill the organism

Back 22

Bacteriostatic

Front 23

Tetracyclines

Back 23

Bacteriostatic

Front 24

Gentamycin

Back 24

Bactericidal

Front 25

Quinolones

Back 25

Bactericidal

Front 26

Erythromycin

Back 26

Bacteriostatic

Front 27

Inhibits transpeptidation enzymes

Back 27

Cell wall inhibitors

Front 28

Cell wall inhibitors

Back 28

Beta lactams

Beta lactam penicillin

Cephalosporins

Konobactams

Carbapenems

Glycopeptides

Fosfomycin

Front 29

Antimicrobial actions

Back 29

Inhibits cell wall synthesis

Inhibits protein synthesis

Inhibits nucleic acid synthesis

Destroy cell membrane

Inhibit essentila metabolites

Front 30

Inhibits transpeptidation

All are bactericidal

Non toxic

Back 30

Beta lactams

Front 31

Beta lactamass enzymes examples

Back 31

Penicillinases

Cephalosporinases

Cephycinases

Carbapenemases

Front 32

Organic acids and are most soluble in water

Back 32

Beta lactam

Front 33

Broadest spectrum ofaction. Active against high level cephalosporinases of Ebteribacteriacea and P. aeruginosa

Back 33

4th generation cephalosporin C4G

Front 34

Inhibits the first step of the peptidoglycan synthesis process and transport precursor

Back 34

Fosfomycin

Front 35

Hydrolyzed by most commonly occuring plasmid and chromosomally B lactamases

Back 35

Monobactams

Front 36

Cefepime, Cefotetan, Cefoxitin, Cefaclor

Back 36

4th generation

Front 37

Wider spectrum, Gram pos cocci but much more active against Enterobacteriaceae and P. aeruginosa

Back 37

3rd generation cephalosporin C3G

Front 38

Narrow spectrum; good gram pos activity and modest in gram neg activity

Back 38

1st generation C1G

Front 39

B lactams with broad spectrum of action. Gram pos except MRSA; Gram neg Pseudomonas aeruginosa and anaerobes

Back 39

Carbapenem

Front 40

Cefunicid, Cefuroxime

Back 40

2nd generation

Front 41

Aztreonam

Back 41

Monobactams

Front 42

Binds with 50s subunit resulting to misreading of mRNA and interferes with aminoacyl - tRNA binding

Back 42

Protein synthesis inhibitors (amonoglycosides, tetracycline)

Front 43

Mistranslation and production of proteins

Back 43

Aminoglycosides

Front 44

Binds with 50s subunit resulting to inhibition of peptidyl transferase and inhibits peptide chain elongation

Back 44

Protein synthesis (clindamycin, erythromycin)