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15 Cards in this Set
- Front
- Back
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Aminoglycosides Mechanism of Action
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Disrupt Protein Synthesis at Ribosome
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Tetrcyclines Mechanism of Action
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Disrupt Protein Synthesis at Ribosome
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Macrolides Mechanism of Action
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Disrupt Protein Synthesis at Ribosome
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Quinolones Mechanism of Action
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Disrupt DNA synthesis (gyrase or topoisomerase)
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Rifampin Mechanism of Action
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Disrupt RNA synthesis (RNA polymerase)
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Sulfonamides Mechanism of Action
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Disrupt Folic Acid Metabolism
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Penicillin Mechanism of Action
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Disrupt Cell Wall Synthesis (peptidoglycan)
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Cephalosporins Mechanism of Action
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Disrupt Cell Wall Synthesis (peptidoglycan)
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Vancomycin Mechanism of Action
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Disrupt Cell Wall Synthesis (peptidoglycan)
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Bacitracin Mechanism of Action
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Disrupt Cell Wall Synthesis (peptidoglycan)
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Antibiotic of choice for MRSA
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Vancomycin
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Name 5 mechanisms of action of Antibiotics
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1. Disrupt cell wall synthesis
2. Disrupts cell membrane/alters permeability 3. Disrupt nucleic acid synthesis 4. Inhibits protein synthesis 5. Disrupt a metabolic pathway |
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What are three general problems that can arise with antibiotic therapy?
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1. allergic reactions
2. Superinfection (disrupt normal microbiota) 3. Direct toxicity (e.g., nephrotoxicity) |
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Aminoglycosides can have what toxic side effects?
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NephrotoxicityOtotoxicity
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beta-lactams action and examples
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Inhibit bacterial cell wall synthesis
(e.g, Penicillin, amoxicillin) |
