Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
91 Cards in this Set
- Front
- Back
|
Bordatella pertussis
|
Azithromycin (Z-pack)
|
|
|
Bact sinusitis
AOM Acute Exacerbation of Chronic Bronchitis |
1. Amoxicillin (High dose for sinusitis)
2. Augmentin 3. Z-pack, if allergic, or Cephalexin (Keflex) |
|
|
CAP with recent ABX
|
Azithromycin (Z-pack)
OR Doxycycline |
|
|
CAP with co-morbidities but NOT MRSA
|
Moxi- OR
Geni- OR Levofloxin (Beta-lactam would not cover atypicals) |
|
|
Respiratory Quinalones = Floxacins
|
Moxi-
Geni- Levofloxin |
|
|
Meningitis
|
Cephatriaxone (Rocephin)
PLUS Vanco |
|
|
UTI, uncomplicated
|
Cipro OR
TMP/SMX (Bactrim) OR Nitrofurantoin (Macrobid) |
|
|
Pylenephritis
|
Cipro
|
|
|
Soft tissue/skin infxn, mild
|
To cover both Strep pyogenes & Staph Aureus:
Doxycyline AND TMP/SMX (Bactrim) |
|
|
Bacterial Vaginitis
|
Metronidazole (Flagyl)
|
|
|
Bacterial Vaginitis
|
Metronidazole (Flagyl)
|
|
|
Vulvovaginal Candidiasis
|
-azole
|
|
|
Bact sinusitis
AOM Acute exacerbation of chronic bronchitis |
1. Amoxicillin (high dose for sinusitis)
2. Augmentin 3. Zpack, if allergick, or Cephalexin (Keflex) |
|
|
CAP with recent aBX
|
Azithromycin (Z-pack)
OR Doxycylcine |
|
|
CAP with comorbidities but NOT MRSA
|
Moxi-
Gemi- Levo- floxacin (Beta-lactam would not cover atypicals) |
|
|
Quinolones
|
Floxacins
|
|
|
Floxacins
|
Quinolones
|
|
|
The respiratory floxacins
|
Moxi-
Gemi- Levo- floxacin |
|
|
The resp quinolones
|
Moxi-
Gemi- Levo- floxacin |
|
|
Meningitis
|
Cephatriaxone (Rocephin)
AND Vanco |
|
|
UTI, uncomplicated
|
TMP/SMX (Bactrim) OR
Cipro OR Nitrofurantion (Macrobid) |
|
|
Trichomonas Vaginalis
|
Metronidazole (Flagyl)
|
|
|
Soft tissue/skin infection, severe
|
MRSA:
TMP/SMX (Bactrim) OR Rifampin OR Linezolid (Zyvox) ($1800) OR Vanco |
|
|
Pseudomonas Aeruginosa
|
Gentamycin OR
Tobramycin OR Amikacin OR Ceftzadine Cefzim - is sometimes referred to as the "Tasmanian Devil," due to its fairly powerful anti-pseudomonal activity.) OR Cipro OR Levofloxin |
|
|
Routine surg prophylaxis (not abdominal)
|
Cefazolin (IV Anceph)
|
|
|
External Genital Warts, topical
|
Podofilax (condylox) OR
Imiguimod (Aldara) |
|
|
Syphilis
|
Benzathine IM
|
|
|
Chlamydia
|
1 dose PO Azithromycin
OR Doxycycline |
|
|
Gonorrhea
|
Cephtriaxone (Rocephin)
|
|
|
C diff
|
Metronizadole (PO preferred)
OR PO Vanco |
|
|
Lyme Disease
(B burgerdorfi) |
Amoxicillin
OR Cefuroxime (Ceftin) OR Doxycycline |
|
|
Prostatitis
UTI Achilles Tendon with rupture Anthrax |
Quinolone= Floxacin
|
|
|
Peptostreptococcus
C perfringins Chlamydia |
Quinolone= Floxacin
|
|
|
M cat
H flu |
Quinolone= Floxacin
|
|
|
Cellulitis, outpt
|
Doxycycline OR TMP/SRX
for MRSA AND Cephalexin (Keflex) for MSSA & Strep pyogenes |
|
|
Hosp cellulitis
|
Vanco
|
|
|
List 1st generation
CEPHALOSPORINS Best for gram ___ |
1st gen = Cephalexin(Keflex)
Cephazolin (Ancef IV) **best for gm POSITIVE** |
|
|
3rd generation
CEPHALOSPORIN Best for gram _____ |
Cephtriaxone (Rocephin)
|
|
|
Cephtriaxone (Rocephin)
|
Best for gm negative
N meningiditis Neisseria gonorrhea - 1 dose |
|
|
Cephalosporin MOA
|
bacteriocidal
similar to pcn beta lactam |
|
|
Quinalones = Floxacins
|
BIG GUNS
Inhibit DNA gyrase action - prevents DNA supercoiling |
|
|
"BIG GUNS"
|
Quinalones = floxacins
|
|
|
Quinalones = floxacins are used for which gm+
|
Gram + (strep, staph, MSSA, listeria)
|
|
|
Quinalones = floxacins are used for which gm neg -
|
pseudomonas, M cat, H flu, & many others.
excellent gm - coverage |
|
|
Quinolones = floxacins are good for gm+, gm-, MSSA, & which others?
|
Atypical
Chlamydia M pneumoniae Anerobes Peptostrepto C perfringens(gas gangrene) Anthrax |
|
|
Quinolones = floxacins not allowed when -
except - |
< age 18
CF, because it will cover pseudomonas |
|
|
Quinolones = floxacins
Drug interaction |
Inhibits CYP450 (esp Cipro)
Increases INR with Warfarin also incr action of theophylline |
|
|
List MACROLIDES
|
Erthyromycin
Clndamycin Azithromycin (Zpack) Clarithromycin (Biaxin) |
|
|
MACROLIDE hint
|
throw-my-sin
|
|
|
1 dose for Chlamydia
|
Azitromycin
|
|
|
DOC for strep if pcn allergic
|
Erythromycin
|
|
|
M avium
Diabetic foot Sinusitis, AOM H Pylori, intra-abd |
Clarithromycin
|
|
|
Toxoplasmic encephalitis
Penumocystic pneumonia |
Azythromycin
|
|
|
Macrolide (thromycin) gm - coverage
|
H flu
M cat H pylori Legionella |
|
|
Chlamydia
B burgerdori (Lyme dz) B pertussis |
Macrolide (thromycin)
|
|
|
Azithromax t 1/2
|
68 hours
|
|
|
Erythomycin t 1/2
|
2hors
|
|
|
#1 cause of C diff & pseudomonas colitis
|
Macrolides (thromycins)
|
|
|
list Carapenem
|
Imipenem = primexem
|
|
|
Imipenem is used for which gm positive
|
Strep
Enterococci MSSA Listeria |
|
|
Imipenem is used for which gm neg -
|
N gonorrhoeae
N meningitidis M cat H flu E coli etc |
|
|
Imipenem is used for which atypicals & anerobes -
|
No atypicals
Peptrostrepto B frag C perfringens (Gas gangrene) |
|
|
List GLYCOPEPTIDE
|
IV Vanco
PO Vanco |
|
|
glycopeptide/vanco AE
|
ototoxic
nephrotoxic |
|
|
glycopeptide/vanco coverage
|
C diff
EXCELLENT GM+ MRSA! MSSA! serious enterococcal infxn coag neg staph |
|
|
Sulfonamides MOA
|
SOFA: inhibits
Synthesis of Folic Acid |
|
|
Sulfa AE
|
Stephens-Johnson rash
|
|
|
List AMINOGLYCOSIDES
|
Gent
Tobra Amikacin Neomycin Topical Streptomycin |
|
|
Aminoglycosides hint
|
-mysin
|
|
|
Macrolides hint
|
-thromysin
|
|
|
Aminoglycosides used for -
but newer drugs are used because- |
Gm Neg
Pseudomonas BUT neprho-oto-toxic |
|
|
List TETRACYCLINEs
|
Tetracycline
Doxacycline Democlocycline Microcycline |
|
|
Demaclocycline is used for
|
SIADH because it causes DI
|
|
|
Prob with tetracycline
|
bugs quickly develop resistance
|
|
|
Plague
Ricksettia (Rky Mtn Spt Fever) Malaria B burgerdorfi (Lyme) Acne |
Microcycline
|
|
|
M pneumoniae
chlamydia TB Parasite protozoa |
Tetracycline
Doxycycline |
|
|
Tetracycline MOA
|
interferes with 30s unit
metab by liver, excreted by kidneys |
|
|
List beta-lactams
|
pcn
cephalosporins carapenem (imipenum) |
|
|
PCN & anti-beta-lactamase combos
|
Amox/clav = PO Augmentin
Amp/sulbactam = IV Unasyn Piper/tazabactan = IV Zosyn Ticar/clavulan = Timetin |
|
|
PCN & anti-beta-lactamase combos are used for -
|
H flu
M cat N gonorrhea B frag |
|
|
OXALODINE (only one)
|
Linezolid = Zyvox $1800
|
|
|
Linezolid (the only oxadine) spectrum
|
E faecalis & facium
MRSA + MSSA + MSSE + SRSE ALL gm + Peptostrepto B frag C perfringins |
|
|
List fluoroquinolones =
quinolones = floxacins |
Older = cipro
Newer = "resp floxacins" Moxi- Gemi- Levofloxin (Levaquin) |
|
|
Fluoroquinolones = floxins spectrum
|
ALL GRAM NEGATIVE!
Most gm + (NOT MRSA) peptostrepto c perfringens chlamydia m pneumoniae |
|
|
Strep pneumoniae
|
Augmentin (amox + clavul)
|
|
|
Metronizadole = flagyl AE
|
No ETOH!
Antabuse-like rxn |
|
|
Metronizadole/flagyl spectrum
|
disrupts anerobe DNA
C diff B frag Peptostrepto Parasites: Amoeba Giardia Trichomonas vaginalis |
|
|
Metronizadole/flagyl will NOT cover -
|
Any gram +
Any gm - except H pylori Gardnerella Vaginalis |
|
|
Gram Neg organisms-
|
Have lipid layer
Stain pink are endotoxic (sepsis is endotoxins released into your body) |
|
|
Gram Pos organisms:
|
Stain purple
have a thick layer of peptoglycan but NO lipid layer |
|
|
Carbapenems - IV only
Imipenem Ertapenem |
Inhibit >90% clinically important bacteria
|
