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5 Cards in this Set
- Front
- Back
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Why is the cell wall essential for (most) bacteria and hence a good target for many antibiotics?
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Cell wall prevents bacteria from lysing as water enters from the external environment.
Thus, if you block cell wall synthesis in dividing bacteria, they will explode b/c the salt concentration is so much higher in them than in the external environment. |
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IV, IM, (oral)
Poorly absorbed orally. G+/G- cocci NOT vs G- rods and anaerobes. Beta lactamase sensitive Pneumococcus Non-lactamase Staphylococcus Neisseria meningitidis Clostridium Treponema pallidum |
Penicillin G
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Orally available version of Penicillin G!
-Note: Oral route NOT good for serious infections. |
Penicillin V
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Penicillins (Beta lactams) that are resistant to beta lactamases and prescribed primarily for Staphylococcus aureus b/c it produces penicillinases!! (4)
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Oxacillin, Nafcillin, Methicillin, Cloxacillin
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What are the 2 key “extended spectrum” beta lactams?
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Amoxacillin, Piperacillin
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