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42 Cards in this Set

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  • Back
Which patients getting GI surgery don't get metronidazole (i.e. just recieve cephazolin or gent)
Upper GI: normal gastric acidity, no obstruction, no bleeding, no prev GI surgery)
Biliary tract: <60, non-diabetic, for elective surgery unlikely to involve exploration of the common bile duct
What endoscopic procedures require antibiotic prophylaxis?
those likely to cause bacteraemia (i.e. not standard endoscopy): involving biliary tract, sclerotherapy, oesophageal dilatation, ERCP
Standard antibiotic regime for endoscopic procedures?
cephazolin or gent prophylaxis

if evidence of biliary stasis: 3d of oral amoxicillin/clavulanate
Antibiotic prophylaxis for hernia repair?
none if no prosthetic material used\
cephazolin if prosthetic material used
Management of peritonitis due to a perforated viscus?
amixicillin
gentamycin\
metronidazole

if therapy >72 hours use piperacillin-tazobactam
Management of patients with SBP?
ceftriaxone
cefotaxime
piperacillin-tazobactam
ticaracillin-clavulanate

If have been on TMP-SMX prophylaxis: enterococcal infection is more common so add amoxy/ampicillin.
Albumin 20% 100ml IV to reduce the risk of hepatorenal syndrome
Antibiotic prophylaxis for SBP in cirrhotic patient
oral norfolxacin/IV cipro for 2 days if GI bleed

If previous SBP/very low protein content in ascietes: use TMP-SMX first line or norflox
Outpatient treatment of mild community-acquired pneumonia
oral amoxicillin or doxy/clarythromycin if atypical org
Inpatient treatment of non-severe community acquired pneumonia
benpen + doxy/clartythromycin
if gram negs on stain/suspected: add gent or substitute cefriaxone/cefotaxime for the ben pen
Management of severe community acquired pneumonia:
IV ceftriaxone + azithro

instead of ceftriaxone use cefotaxime/benpen + gent

i.e. same as non-severe (moderate) CAP where gram negative bacilli are identified in sputum/blood
Indications for in-patient treatment in community acquired pneumonia?
ONE of above:
Clinical
respiratory rate greater than 30 breaths/min
systolic blood pressure less than 90 mm Hg
oxygen saturation less than 92%
acute onset confusion.
Investigations
arterial (or venous) pH less than 7.35
partial pressure of oxygen (PaO2) less than 60 mm Hg
multilobar involvement on chest X-ray.
Define severe pneumonia?
At least 2 of CORB:
C = acute confusion

O = oxygen saturation 90% or less

R = respiratory rate 30 breaths or more per minute

B = systolic blood pressure less than 90 mm Hg or diastolic blood pressure 60 mm Hg or less
Antibiotic prophylaxis for cardiac surgery
cephazolin
OR
di/fluclox + gent
Indications for pre-operative vancomycin prophylaxis in any surgery?
preoperative patients infected or colonised with a methicillin-resistant S. aureus (MRSA) strain (health care–associated or community-associated) currently or in the past
patients having major surgery who are at high risk for MRSA colonisation (eg those who have resided for longer than 5 days in a health care facility where MRSA is endemic)
patients undergoing prosthetic cardiac valve, joint or vascular surgery where the procedure is a re-operation (return to theatre or revision)
patients hypersensitive to penicillins and/or cephalosporins
Indications for post-operative vancomycin?
cardiac surgery and vascular surgery
Antibiotic prophylaxis for head, neck, thoracic surgery?
incision/prosthetic material\
use cephazolin- usually single dose is enough but if procedure is not completed within 3 hours of initiating prophylaxis a 2nd dose should be given
Prophylaxis for lower limb amputation
risk of clostridial infection
benpen + metro
Prophylaxis before neurosurgery
cephazolin or di/fluclox
prophylaxis for termination of pregnancy
cephazolin + metro
Prophylaxis for c-section
cephazolin
Prophylaxis for orthopaedia surgery
cephazolin or di/fluclox
Prophylaxis for turp
ciprofloxacin 1 hr before procedure
prophylaxis before prostatectomy/ urological procedure with evidence of a UTI
gentamycin
Are prophylactic antibiotics used for surgery on the brachial/carotid arteries?
no, unless prosthetic material is used
Indications for antibiotic prophylaxis in vascular surgery?
Arterial reconstructive surgery involving the abdominal aorta and/or the lower limb, particularly if a groin incision is involved or with the implantation of foreign material
prophylactic antibiotics in vascular surgery
cephazolin
OR
di/fluclox + vancomycin

if vancomycin indicated use vanc + gent
Antibiotic cover for human bites/clenched fist injuries?
amoxicillin + clavulanate
cover eikinella
Common side effects of augmentin
>10% GI (diarrhoea)
1-10% rash, vaginitis, mucositis
<1%: ALP rise, cholestatic jaundice, hepatitis, thrombocytosis
How many dTPA doses should a kid have had by the age of 17?
5
How do you vaccinate an adult who has not had their primary course of tetanus vaccination?
Give 3 doses dT at 4 weeks apart and a booster 10/20 years later
Management of a tetanus prone wound?
if no bouster in 5 years- give booster
if doubt adequacyy of immunization- give Ig + toxoid
Antibiotic cover for human bites/clenched fist injuries?
amoxicillin + clavulanate
cover eikinella
Common side effects of augmentin
>10% GI (diarrhoea)
1-10% rash, vaginitis, mucositis
<1%: ALP rise, cholestatic jaundice, hepatitis, thrombocytosis
How many dTPA doses should a kid have had by the age of 17?
5
How do you vaccinate an adult who has not had their primary course of tetanus vaccination?
Give 3 doses dT at 4 weeks apart and a booster 10/20 years later
Management of a tetanus prone wound?
if no bouster in 5 years- give booster
if doubt adequacyy of immunization- give Ig + toxoid
Antibiotic cover for human bites/clenched fist injuries?
amoxicillin + clavulanate
cover eikinella
Common side effects of augmentin
>10% GI (diarrhoea)
1-10% rash, vaginitis, mucositis
<1%: ALP rise, cholestatic jaundice, hepatitis, thrombocytosis
How many dTPA doses should a kid have had by the age of 17?
5
How do you vaccinate an adult who has not had their primary course of tetanus vaccination?
Give 3 doses dT at 4 weeks apart and a booster 10/20 years later
Management of a tetanus prone wound?
if no bouster in 5 years- give booster
if doubt adequacyy of immunization- give Ig + toxoid
Are prophylactic antibiotics indicated in simple scalp lacerations?
no