Antibiotic - Doc

Front 1

Enterococcus faecalis

Serious Infection
(endocarditis, meningitis, pylenonephritis with bacteremia)

Back 1

DOC: Ampicillin (or penicillin G) + (gentamicin or streptomycin)

ALT:Vancomycin + (gentamicin or streptomycin)
Linezolid, Daptomycin, Tigecycline

Hint 1

(GRAM POSITIVE COCCI)

Front 2

E. Faecium
Recommend consultation with infectious disease specialist

Back 2

DOC:Linezolid, Synercid, Daptomycin, Tigecycline
***more resistant than E. Faecalis

Hint 2

GRAM POSITIVE COCCI)

Front 3

Staphylococcus aureus/epidermis

Methicillin (oxacillin)-sensitive

Back 3

DOC: Penicillinase-Resistant
ALT: FGC, Bactrim, clindamycin, Unasyn, amox-clav

Hint 3

(GRAM POSITIVE COCCI)

Front 4

Streptococcus (groups A, B, C, G and Bovis)

Back 4

DOC:Penicillin G or V or ampicillin

ALT:Erythromycin, FGC, (erythro/azithro/clarithromycin)

Hint 4

(GRAM POSITIVE COCCI)

Front 5

Streptococcus Pneumoniae

Penicillin-sensitive
(MIC < 0.1mcg/mL)

Back 5

DOC: Penicillin G or V or ampicillin

ALT: Erythromycin, FGC, doxcycline, azithromycin, clarithromycin

Hint 5

(GRAM POSITIVE COCCI)

Front 6

Streptococcus, viridians group

Back 6

DOC: Penicillin G ± gentamicin

ALT: TGC, (erythro/azithro/clarithromycin), or
vancomycin ± gentamicin

Hint 6

(GRAM POSITIVE COCCI)

Front 7

Streptococcus Pneumoniae

Penicillin-intermediate
(MIC <0.1-1.0 mcg/mL)
*recommend consultation

Back 7

DOC: High dose penicillin
(12 million units/day for adults) or Ceftriaxone or cefotaxime

ALT: TGFQ—Levo/Moxi/Gemifloxacin
telithromycin, or vancomycin

Hint 7

(GRAM POSITIVE COCCI)

Front 8

Streptococcus Pneumoniae

Penicillin-resistant
(MIC >1.0 mcg/mL)

Back 8

DOC: Vancomycin ± Rifampin

ALT: TGC, telithromycin,
(Levo/Moxi/Gemifloxacin)—TGFQ

Hint 8

(GRAM POSITIVE COCCI)

Front 9

Enterococcus faecalis

UTI

Back 9

DOC:Ampicillin, amoxicillin

ALT:Fosfomycin or nitrofurantoin

Hint 9

(GRAM POSITIVE COCCI)

Front 10

Staphylococcus aureus/epidermis

Methicillin (oxacillin)-resistant

Back 10

DOC:Vancomycin ±
(gentamcin or Rifampin)

ALT:Bactrim, doxycycline, clindamycin, linezolid, Synercid, daptomycin or tigecycline

Hint 10

(GRAM POSITIVE COCCI)

Front 11

Clostridium perfringens

Back 11

DOC: Penicillin G ± clindamycin

ALT: Metronidazole, clindamycin, doxcycline, cefazolin, (imi/mero/ertapenem)

Hint 11

(GRAM POSITIVE BACILLI)

Front 12

Clostridium Difficile

Back 12

DOC: Oral metronidazole,
oral vancomycin

Hint 12

(GRAM POSITIVE BACILLI)

Front 13

Moraxella (Branhamella) catarrhalis

Back 13

DOC: Amox-clav, Unasyn

ALT: Bactrim, doxycycline
(erythr/clarithromycin),
SGC, TGC, or TGC PO

Hint 13

(GRAM NEGATIVE COCCI)

Front 14

Neisseria gonorrhoae

Disseminated gonococcal infection
(give concomitant treatment for Chlamydia trachomatis)

Back 14

DOC: Ceftriaxone or cefotaxime

ALT: Oral followup:
Cefodoxime,
Cipro/levofloxacin

Hint 14

(GRAM NEGATIVE COCCI)

Front 15

Neisseria Meningitides

Back 15

DOC: Penicillin G

ALT: TGC

Hint 15

(GRAM NEGATIVE COCCI)

Front 16

Neisseria gonorrhoae

Uncomplicated Infection

Back 16

DOC: Ceftriaxone or cefotaxime or cefpodoxime

ALT: (Cipro/Levofloxacin)

Hint 16

(GRAM NEGATIVE COCCI)

Front 17

Chlamydia pneumonia

Back 17

DOC: Doxycycline

ALT: (Erythro/Azithro/Clarithromycin)
Telithromycin or FQ

Hint 17

(MISCELLANEOUS MICROORGANISMS)

Front 18

C. Trachomatis

Back 18

DOC: Doxcycline or azithromycin

ALT: Levo/ Ofloxacin

Hint 18

(MISCELLANEOUS MICROORGANISMS)

Front 19

Mycoplasma pneumonia

Back 19

DOC: Erythr/azithro/clarithromycin

ALT: Doxycycline or FQ

Hint 19

(MISCELLANEOUS MICROORGANISMS)

Front 20

Treponema Pallidum

Neurosyphilis

Back 20

DOC: Penicillin G

ALT: Ceftriaxone

Hint 20

(SPIROCHETES)

Front 21

Treponema Pallidum

Primary or secondary

Back 21

DOC: Benzathine penicillin G

ALT: Doxycycline or ceftriaxone

Hint 21

(SPIROCHETES)

Front 22

Borrelia burgdorferi

Choice depends on stage of disease

Back 22

DOC:(Ceftriaxone/Cefotaxime) or cefuroxime axetil,
doxycycline, amoxicillin, high-dose penicillin, or azithromycin

Hint 22

(SPIROCHETES)

Front 23

Acinetobacter spp

Back 23

DOC:Imi/Meropenem ± AG (amikacin)

ALT:Ciprofloxacin, Unasyn,
colistin, or tigecycline

Hint 23

(GRAM NEGATIVE BACILLI)

Front 24

Bacteroides fragilis
(and others)

Back 24

DOC:Metronidazole

ALT:BLIC, clindamycin, cephamycins, or cabapenem

Hint 24

(GRAM NEGATIVE BACILLI)

Front 25

Enterobacter spp

Back 25

DOC:(Imi/Mero/Ertapenem) or cefepime ± AG

ALT:(Cipro/Levofloxacin) tigercycline, (Zosyn, ticarcillin-clav)

Hint 25

(GRAM NEGATIVE BACILLI)

Front 26

Escherichia coli

Meningitis

Back 26

DOC:TGC or meropenem

Hint 26

(GRAM NEGATIVE BACILLI)

Front 27

Escherichia coli

Systemic Infection

Back 27

DOC: TGC

ALT: Ampicillin-sulbactam, FGC, BL/BLI, FQ, imipenem, meropenem

Hint 27

(GRAM NEGATIVE BACILLI)

Front 28

Escherichia coli

UTI (most oral agents:
check sensitivities)

Back 28

DOC: Ampicillin, amox-clav, doxycyline, or cephalexin

ALT: AG, FGC, nitrofurantoin, FQ

Hint 28

(GRAM NEGATIVE BACILLI)

Front 29

Gardnerella vaginalis

Back 29

DOC: Metronidazole

ALT: Clindamycin

Hint 29

(GRAM NEGATIVE BACILLI)

Front 30

Haemophilus influenzae
Meningitis

Back 30

DOC: Cefotaxime or ceftriaxone

ALT: Meropenem or chloramphenicol

Hint 30

(GRAM NEGATIVE BACILLI)

Front 31

Haemophilus influenzae
Other infections

Back 31

DOC: BLIC, (if B-lactamase-negative) Ampicillin or amoxicillin

ALT:Bactrim, cefuroxime, (Azithro/Clarithromycin) or FQ

Hint 31

(GRAM NEGATIVE BACILLI)

Front 32

Klebsiella pneumonia

Back 32

DOC: TGC (UTI only—AG)

ALT: Cefuroxime, FQ, BLIC,
(Imi/Mero/Ertapenem)

Hint 32

(GRAM NEGATIVE BACILLI)

Front 33

Legionella spp

Back 33

DOC: Erythromycin ± Rifampin or FQ

ALT: Bactrim, clarithromycin, azithromycin, or doxycycline

Hint 33

(GRAM NEGATIVE BACILLI)

Front 34

Pasteurella multocida

Back 34

DOC: Penicillin G, ampicillin, amoxicillin

ALT: Doxycycline, BLIC, Bactrim or ceftriaxone

Hint 34

(GRAM NEGATIVE BACILLI)

Front 35

Proteus Mirabilis

Back 35

DOC: Ampicillin

ALT: Bactrim, most antibiotics except PRP

Hint 35

(GRAM NEGATIVE BACILLI)

Front 36

Proteus (indole-positive) (including Providencia retgeri, Morganella morganii, and Proteus vulgaris)

Back 36

DOC: TGC, or FQ

ALT: BLIC, aztreonam, imipenem, or TGC PO

Hint 36

(GRAM NEGATIVE BACILLI)

Front 37

Providencia stuartii

Back 37

DOC: TGC or FQ

ALT: Bactrim, aztreonam,
(Imi/Mero/Ertapenem)

Hint 37

(GRAM NEGATIVE BACILLI)

Front 38

Pseudomonas aeruginosa

Back 38

DOC: Cefepime, ceftaxidime, Zosyn, or
ticarcillin-clav + AG

ALT: (Cipro, levofloxacin), aztreonam, (Imi/Meropenem) or colistin

Hint 38

(GRAM NEGATIVE BACILLI)

Front 39

Salmonella typhi

Back 39

DOC: (Cipro/Levofloxacin) (Ceftriaxone, or cefotaxime)

ALT: Bactrim

Hint 39

(GRAM NEGATIVE BACILLI)

Front 40

Serratia marcescens

Back 40

DOC: Piperacillin-tazobactam, ticarcillin-clav, or TGC ± gentamicin

ALT: Bactrim, cipro, levo, aztreonam, (Imi/mero/ertapenem)

Hint 40

(GRAM NEGATIVE BACILLI)

Front 41

Stenotrophomonas (Xanthomonas) maltophilia

Generally very resistant to all antimicrobials

Back 41

DOC: Bactrim

ALT: check sensitivities to ceftazidime, ticarcillin-clav, doxycycline and minocycline

Hint 41

(GRAM NEGATIVE BACILLI)

Front 42

Pseudomonas aeruginosa
UTI only

Back 42

DOC: AG

ALT: Ciprofloxacin, Levofloxacin

Hint 42

(GRAM NEGATIVE BACILLI)