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10 Cards in this Set
- Front
- Back
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Penicillins |
Inhibit cell wall synthesis Bactericidal Gram-positive, gram-negative cocci B-lactam antibiotics Target transpeptidase |
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Cephalosporins |
Inhibit cell wall synthesis Bactericidal Gram-positive, gram-negative B-lactam antibiotics Target transpeptidase More resistant to B-lactamase enzymes than penicillin |
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Vancomycin |
Inhibit cell wall synthesis Bactericidal Gram-positive B-lactam antibiotics Inhibit NAG and NAM in peptidoglycan |
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Bacitracin |
Inhibit cell wall synthesis Bactericidal Gram-negative Inhibit peptidoglycan precursors from moving to cell wall |
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Isoniazid |
Inhibit cell wall synthesis Bactericidal Mycobacteria Inhibit mycolic acid synthesis |
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Chloramphenicol |
Inhibit protein synthesis Bacteriostatic Gram-positive, gram-negative, aerobe, anaerobe Use as last resort because it also impacts protein synthesis in bone marrow. Binds to 50S and inhibits peptide bonds between a.a. residues. |
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Aminoglycosides |
Inhibit protein synthesis Bactericidal Aerobic, gram-negative rods (not anaerobic because it needs O2 for transport into cell) Binds to 30S. mRNA is read incorrectly |
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Tetracyclines |
Inhibit protein synthesis Bacteriostatic Gram-positive, gram-negative Binds to 30S and interferes with tRNA attachment |
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Macrolides |
Inhibit protein synthesis Bacteriostatic Gram-positive Binds to 50S |
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Lincosamides |
Inhibit protein synthesis Bacteriostatic Aerobic, gram-positive cocci, anaerobes Binds to 50S |
