Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
31 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Penicillun notatum |
Alexander flemming |
|
|
|
Term for mechanism of inhabition |
Antibiosis |
|
|
|
Inhibit the growth of the another organism |
Antibiotic |
|
|
|
Salvarsan |
Paul erlich |
|
|
|
Sulfanilamide |
Prontosil red |
|
|
|
For clinical trial for penicillin |
Howard and chain |
|
|
|
Discover prontosil red |
Domagk |
|
|
|
Broadest spectrum |
Tetracyline |
|
|
|
Kill microbes directly |
Batericidal |
|
|
|
Prevent microbes for growing |
Bacteristatic |
|
|
|
All protein synthesis except |
Aminoglycosides |
|
|
|
Result of 2 drugs is equal to the result of the more effective drug |
Autonomous/ indifferent |
|
|
|
Cancellation effect Static + cidal Example Tetracycline + Amoxicillin |
Antagonistic (1+1=0) |
|
|
|
Effective on actively dividing cells |
Cidal |
|
|
|
Inhibit the growth of the microorganism |
Static |
|
|
|
Static + static
Example Co- trmoxale(sulfamethoxale + trimethoprim) |
Synergistic (1+1=3) |
|
|
|
Cidal + cidal except penicillin + aminoglycoside( synergism) |
Addictive (1+1=2) |
|
|
|
B-lactamase inhibitor + penicillin Example Co- amoxiclav -} clavulanic acid + amox Sultamicillin -} sulbactam + ampicillim Piptazo -} tazobactam+ piperacillin |
Potentiation (0+1=2) |
|
|
|
Suicide inhibitor |
Potentiation |
|
|
|
Moa Cell syntesis |
Cell wall synthesia |
|
|
|
Cycloserine Synthesis of cell wall precursor |
Cytoplasm |
|
|
|
Glycopeptide, bacitracin Synthesis of new cell wall sub unit attached to the lipid carrier |
Cytoplasmic membrane |
|
|
|
Beta lactams Attachment of new wall unit growing PG |
Cell wall |
|
|
|
... |
Beta lactam |
|
|
|
... |
... |
|
|
|
Moa Inhibit cell wall synthesis |
Beta lactam |
|
|
|
Moa Cross linking PG
Adr Hypersensitivity reaction -) anahylaxis |
Penicillin |
Epenephrine doc for Anahylaxis |
|
|
Doc for anaphylaxis |
Epinephrine |
|
|
|
Prototype DOC for staphylococci, streptococcus,,,,,,,,,, |
Penicillin G |
|
|
|
Orally form For minor infection |
Penicillin V |
|
|
|
Treatmentof uncomplicated pneumococcal pneumonia and gonorrhea |
Procaine and penicillin G |
|
