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18 Cards in this Set
- Front
- Back
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Enfuvirtide (T-20) |
Viral fusion and entry blocker, mimics HR2 and prevents membrane fusion |
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Maraviroc |
viral fusion and entry blocker, blocks CCR5 |
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Palivuzumab |
viral fusion and entry blocker used for RSV |
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Amantidine, Rimantidine |
viral uncoating inhibitor, used for Influenza A |
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Raltegravir |
blocks HIV-1/2 integrase from inegrating DNA into host |
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Acyclovir |
nucleoside that integrates into viral DNA chain, traps DNA polymerase |
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Foscarnet |
inhibits viral DNA and RNA polymerase |
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Adefovir |
competitively inhibits viral DNA polymerase and reverse transcriptases higher affinity for HBV polymerase than human |
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Lamivudine (3-TC) |
NRTI nucleoside drug that competitively inhibits viral reverse transcriptase used for HBV |
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Entecavir |
NRTI competitively inhibits DNA polymerase weak inhibitor of cellular and mitochondrial polymerases |
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Ribavirin |
inhibits viral RNA polymerase mulitple MOA, poorly understood drug of choice for RSV |
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Zidovudine (AZT) |
NRTI |
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Nevirapine, Efavirenz |
NNRTI binds p66 pocket of HIV reverse transcriptase |
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Boceprevir, Telaprevir |
block cleavage of precursor protein in HCV |
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Peginterferon alfa |
long-lasting exogenous interferon
signals cell production of anti-viral proteins used for HBV |
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Atazanvir, Ritonavir, Saquinavir |
HIV protease inhibitors |
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Oseltamvir, Zanamavir |
neuramindase inhibitor used for influenza A and B blocks progeny release |
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Ganciclovir |
inhibits viral DNA polymerase better oral bioavailabilty than acicyclovir used for CMV infections |
