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8 Cards in this Set

  • Front
  • Back
phenytoin (Dilantin)
inhibits Na channels in post-synaptic neuron
narrow therapeutic range
given IV to stop status epilepticus
severe rash

very alkaline
fosphenytoin (Cerebyx)
like phenytoin but more water soluble
topiramate (Topomax)
inhibits Na channels (augmenting GABA receptors)
prevention of migraines
carbamazepine (Tegretol)
tx of: 1) grand mal seizures
2) complex seizures
increase sensitivity of GABA receptors
adverse SE - idiosyncratic hyperactivity
valproic acid (Depakene)
effective against ALL types of seizures

enteric coated = Depakote
avail in IV = Depacon
lamotrigine (Lamictal)
tx of partial seizures and tonic-clonic seizures
also for depression in bipolar

adverse - Stevens-Johnson syndrome (Life threatening rash)
levetiracetam (Keppra)
adjunct in tx of partial and tonic-clonic seizures