Anti-Protozoal Drugs

Front 1

Proguanil

Back 1

Clinical Uses: prophylactic and suppressive activity in sporozoite induced P.falciparum malaria; suppresses acute attacks of P.vivax malaria

Front 2

Primaquine

Back 2

Clinical Uses: used to treat latent forms (hypnozoiticidal) of P.vivax and P.ovale to prevent relapse; prophylaxis - active against exo-erythrotic schizonts; gametocytocidal for all malarial parasites;
CI: patients with G6PD deficiency, may cause acute intravascular hemolysis

Front 3

Chloroquine

Back 3

Clinical Uses: TOC for P.vivax, P.ovale, P.malariae, and uncomplicated P.falciparum malaria;
SAFE in PREGNANCY!

Front 4

Quinine/Quinidine

Back 4

Clinical Uses: treatment of severe illness due to chloroquine-resistant strains of P.falciparum; gametocytocidal for P.vivax and P.malariae;
AE: cinchonism, hypoglycemia, hypotension, thrombocytopenia;
CI: PREGNANCY

Front 5

Pyrimethamine + Sulfadioxine

Back 5

Clinical Uses: prophylaxis of mildly chloroquine-resistant P.falciparum malaria; used in combo with Quinine in the treatment of uncomplicated, multi-resistant P.falciparum malaria;
SAFE in PREGNANCY!

Front 6

Metronidazole

Back 6

Clinical Uses: used to treat ANAEROBIC bacteria; amebiasis, trichomoniasis, giardiasis, dracunculiasis; hepatic abscesses and other extra hepatic amebic infections;
AE: nausea, headache, metallic aftertaste;
CI: alcohol use should be avoided

Front 7

Nifurtimox

Back 7

Clinical Uses: acute Chaga's disease;
AE: nausea, vomiting, abdominal pain, insomnia, seizures, polyneuritis;
CI: should be avoided in early pregnancy

Front 8

Sodium Stilbogluconate

Back 8

Clinical Uses: leishmaniasis and KALA AZAR