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42 Cards in this Set
- Front
- Back
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Directly acting cholinomimetic: physiological neurotransmitter
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Ach
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Directly acting cholinomimetic: diagnose bronchial asthma
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Methacholine
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Directly acting cholinomimetic: post operative ileus & urinary retention
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Bethanecol
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Directly acting cholinomimetic: glaucoma
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Carbachol
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Directly acting cholinomimetic alkaloid: glaucoma & Sjrogrens syndrome
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Pilocarpine
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Indirectly acting cholinomimetic: Reversible inhibitor for Glaucoma
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physostigmine
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Indirectly acting cholinomimetic: Reversible inhibitor for Rx of Myasthenia Gravis..Reverse competitive blockade at nmj
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neostigmine and pyridostigmine
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Indirectly acting cholinomimetic: Reversible inhibitor for Diagnosis of Myasthenia Gravis
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Edrophonium
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Indirectly acting cholinomimetic: Reversible inhibitor for Alzheimer Disease
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Donepezil, Tacrine, Rivastigmine
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Indirectly acting cholinomimetic: Irreversible inhibitor for Insecticide use in chemical warfare
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Parathion, Malathion, nerve gases (Sarin, Tabun)
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Indirectly acting cholinomimetic: Irreversible for glaucoma
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Ecothiophate
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Antimuscarinic: mydriatic refractive testing, uveitis, iritis
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Homatropine, Tropicamide, Cyclopentolate
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Antimuscarinic: Organophosphate Mushroom poistoning
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Atropine
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Antimuscarinic: Motion Sickness
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Scopolamine
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Antimuscarinic: Drug induced parkinsonism
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Benztropine, Biperidine, Trihexphenidyl
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Antimuscarinic: Bronchial asthma
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Ipatropium
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Antimuscarinic: Urinary urgency
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Oxybutynin
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Antimuscarinic: Cystitis
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Glycopyrrolate
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Antinicotinic: Ganglion Blocker (not used)
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Hexamethonium, Mecamylamine
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Antinicotinic: NM blocker used as skeletal muscle relaxant during general anesthesia.
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Depolarizing blocker- Succinyl Choline (sCH - genetically determine atypical pseudocholinesterase enzyme will develop respiratory paralysis).
Competitive blockers- D-tubocurarine, Pancuronium, Vecuronium |
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Adrenergic Agonist: alpha, beta 1, beta 2..for cardiac arrest, glaucoma, anaphylaxis
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Epinephrine
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Adrenergic Agonist: alpha, beta 1, no activity on beta 2...short term hypotensive emergency
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Norepinephrine
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Adrenergic Agonist: D1 = D2 >> Beta >> Alpha...cardiogenic shock
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Dopamine
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Adrenergic Agonist: Beta 1...cardiogenic shock
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Dobutamine
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Adrenergic Agonist: Beta 1.. Bronchial asthma, cardiac arrest, heart block
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Isoproterenol
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Adrenergic Agonist: alpha 1 for short term hypotensive emergency
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Phenylephrine
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Adrenergic Agonist: alpha 2 at vasomotor center for hypertension
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Clonidine, alpha-methyldopa
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Adrenergic Agonist: alpha 1 as nasal decongestant - rhinitis, hay fever
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Oxymetazoline, Xylometazoline, Ephedrine, Pseudoephedrine
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Adrenergic Agonist: Block catecholamine reuptake..abuse
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Cocaine
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Adrenergic Agonist: CNS stimulants for ADHD and Narcolepsy
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Dextroamphetamine, methylphenidate
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Adrenergic Agonist: Beta 2 stimulant for bronchial asthma and premature labor
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Albuterol, Terbutaline, and Ritodrine
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Adrenergic Antagonist: NON-selective alpha 1 and 2 blocker to decrease TPR and BP for HTN of pheochromocytoma
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Phenoxybenzamine, Phentolamine
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Adrenergic Antagonist: Selective alpha 1 blocker to improve urinary symptoms in BPH (decreased TPR and BP) for Benign Prostatic Hypertrophy
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Prazosin, Terazosin, and Tamsulosin
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Adrenergic Antagonist: Beta 1 and 2 blocker to decrease TPR, BP, AV conduction, Cardiac work load for HTN, Angina, performance anxiety, essential tremors, pheochromocytoma, cardiac arrhythmias, migraine prophylaxis, and thyrotoxicosis
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Propranolol
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Adrenergic Antagonist: Beta 1 and 2 blocker for HTN and Angina - long duration of action
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Nadolol
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Adrenergic Antagonist: Beta 1 and 2 blocker to decrease aqueous humor formation for glaucoma
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Timolol
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Adrenergic Antagonist: Beta 1 adn 2 blocker for HTN and angina as a partial agonist
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Pindolol
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Adrenergic Antagonist: Blocks K+ channels for cardiac arrythmias
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Sotalol
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Adrenergic Antagonist: alpha and beta blocker for HTN emergency and cardiac failure
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Labetolol and Carvedilol
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Adrenergic Antagonist: Beta 1 > Beta 2 blocker...safer beta blockers in asthmatics and diabetic patients
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Metoprolol, Atenolol, and Acebutalol
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Adrenergic Antagonist: short plasma half life for supraventricular arrythmias
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Esmolol
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Adrenergic Antagonist: long duration of action for Glaucoma
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Betaxolol
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