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14 Cards in this Set

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  • Back
Penicilin
inhibit peptide bridge PTG
Vancomycin
inhibits glycan chains inhibiting formation of PTG and cell wall construction
Bacitracin
inteferes with transport of PTG precursors across cytoplasmic membrane
Aminoglycosides
binds to 30s unit: cause distortion and malfunction of ribosome misreading of mRNA
tratracyline
binds 30s unit: block tRNA attachement to ribosome
prevent continuation of protein syntesis
macrolides
bind to 50s ribosome prevents of continution of protein synthesis (judge of choice if allergic to penicllin)
Lincosamides
binds to 50s ribosomal subunit prevents protein syn.
Fluoroquinolones
inhibit DNA gyrase
Rifamycin
block prokaryotic RNA polymerase
Sulfonamide
block metabolic pathways
polymixn B
damage cell membrane also effect eukaryotic
Rifampin
inhibit mRNA syntheis
Streptomycin
inhibits protein synthesis
Isoniazid, ethambutol, pyrazinadmide
I: inhibit mycolic acid
E:Inhibits enzymes cell wall synthesis
P: unknown