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14 Cards in this Set
- Front
- Back
Penicilin
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inhibit peptide bridge PTG
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Vancomycin
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inhibits glycan chains inhibiting formation of PTG and cell wall construction
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Bacitracin
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inteferes with transport of PTG precursors across cytoplasmic membrane
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Aminoglycosides
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binds to 30s unit: cause distortion and malfunction of ribosome misreading of mRNA
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tratracyline
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binds 30s unit: block tRNA attachement to ribosome
prevent continuation of protein syntesis |
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macrolides
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bind to 50s ribosome prevents of continution of protein synthesis (judge of choice if allergic to penicllin)
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Lincosamides
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binds to 50s ribosomal subunit prevents protein syn.
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Fluoroquinolones
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inhibit DNA gyrase
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Rifamycin
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block prokaryotic RNA polymerase
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Sulfonamide
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block metabolic pathways
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polymixn B
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damage cell membrane also effect eukaryotic
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Rifampin
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inhibit mRNA syntheis
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Streptomycin
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inhibits protein synthesis
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Isoniazid, ethambutol, pyrazinadmide
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I: inhibit mycolic acid
E:Inhibits enzymes cell wall synthesis P: unknown |