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26 Cards in this Set

  • Front
  • Back
Pigmented upper surface
Animal pole (Anterior)
Unpigmented lower region, having an accumulation of yolk granules.
Vegetal pole (Posterior)
Cleavage
Occurs after fertilization (fusion of the male and female nuclei) - mitotic divisions in which cells become smaller between each successive division.
Blastula
After about 12 division cycles from cleavage
Blastocoel
fluid-filled cavity; surrounded by small cells from above large yokly cells from below.
Mesoderm
Gives rise to muscle, cartilage, bone, and other internal organs like heart, blood, kidney; It is present in the blastula as an equatorial band.
Endoderm
Gives rise to the gut, lungs, liver.
Animal Pole
gives rise to the ectoderm
Ectoderm
forms both the epidermis and the nervous system
Gastrulation
Drf cells; damatic rearrangement of cells - the endoderms and mesoderm move inside, and the basic body plan of the tadpole is established. The mesoderm gives rise to a rod-like structure called the Notochord.
Neurulation
Process that begins shortly after gastrulation; the notochord folds to form the neural tube and gives rise to the brain and spinal cord.
Organogenesis
Specialized cells such as muscle cartilage, and neurons differentiate
William Harvey (1651)
Concludes all organisms come from eggs
Marcello Malphigi (1672)
Publishes microscopy of chick development
What are the 3 major approaches to Development?
1) Anatomical Approaches
2) Experimental Approaches
3) Genetic Approaches
What are the Anatomical Approaches of Development?
**Look and See**
-Comparative Embryology (our main emphasis)
-Evolutionary Embryology
-Teratology (birth defects)
-Mathematical modeling
What are the Experimental Approaches of Development?
**Manipulation of embryos and their molecular components**
-Removal or grafting of embryo pieces
-Ablation of cells
-Treating tissues with chemical substances
-Overexpressing or blocking gene functions
What are the genetic approaches of Development?
-Classic Genetics: randomly mutagenize genome, observe phenotype & map gene.
-Reverse genetics: knock out gene of interest and observe phenotype
-Modern molecular genetics: genome analysis, DNA sequencing, gene expression analysis.
Neurulation
Process that begins shortly after gastrulation; the notochord folds to form the neural tube and gives rise to the brain and spinal cord.
Organogenesis
Specialized cells such as muscle cartilage, and neurons differentiate
William Harvey (1651)
Concludes all organisms come from eggs
Marcello Malphigi (1672)
Publishes microscopy of chick development
What are the 3 major approaches to Development?
1) Anatomical Approaches
2) Experimental Approaches
3) Genetic Approaches
What are the Anatomical Approaches of Development?
**Look and See**
-Comparative Embryology (our main emphasis)
-Evolutionary Embryology
-Teratology (birth defects)
-Mathematical modeling
What are the Experimental Approaches of Development?
**Manipulation of embryos and their molecular components**
-Removal or grafting of embryo pieces
-Ablation of cells
-Treating tissues with chemical substances
-Overexpressing or blocking gene functions
What are the genetic approaches of Development?
-Classic Genetics: randomly mutagenize genome, observe phenotype & map gene.
-Reverse genetics: knock out gene of interest and observe phenotype
-Modern molecular genetics: genome analysis, DNA sequencing, gene expression analysis.