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48 Cards in this Set

  • Front
  • Back

Anesthetic agent

Any drug used to induce a loss of sensation with or without unconsciousness

Adjunct

A drug that is not a true anesthetic, but that is used during anesthesia to produce other desired effects

What are the effects of adjuncts?


Sedation


Muscle relaxation


Analgesia


Reversal


Neuromuscular blockade


Parasympathetic blockade

What are the routes of administration for anesthetic agents and adjuncts?

Inhalant


Injectable


Oral


Topical

When do you administer anesthetic agents and adjuncts?

Preanesthetic


Induction


Maintenance

What are the different classifications for anesthetic agents? (Based on principal effect)

Local


General


Sedatives


Tranquilizers


Analgesics


Neuromuscular blockers


Anticholinergic agents


Reversal agents

What are agonists?

Drugs that bind to and stimulate target tissue

Are most anesthetic agents and adjuncts considered agonists?

Yes

`What are antagonists?

Drugs that bind to target tissue but do not stimulate

Are reversal agents agonists or antagonists?

Antagonists

What are agonist-antagonist or partial agonists?

Drugs that partially stimulate target tissue and are used to block pure agonists

Name a class of drugs that are partial agonists/agonist-antagonist

Opioids

What are analgesics?

Drugs that offer some pain relief

Are most general anesthetics analgesics?

NO

When do you provide analgesics?

Pre and post operatively

Do true analgesics provide general anesthesia?

No

Should you mix drugs in a single syringe?

No, unless they are compatible

If there is a precipitate when drugs are mixed, should you administer it?

NO

Are most anesthetic agents and adjuncts water soluble?

Yes

What do preanesthetic medications do?

Calm or sedate an excited animal


Minimize adverse drug effects


Reduce dose of concurrent drugs


Analgesia


Muscle relaxation


Smoother induction and recovery

What are the routes of administration for preanesthetic medications?

SubQ: Slowest onset, longest duration


IM: Faster onset, shorter duration


IV: Fastest onset, shortest duration

What are anticholinergics?

Drugs that act against the parasympathetic nervous system

What do preanesthetic anticholinergics do?

Block acetylcholine

What is acetylcholine?

A neurotransmitter that acts as an inhibitor

What does blocking acetylcholine do?

Prevents and treats bradycardia


Decreases salivary secretions

What are two preanesthetic anticholinergics?

Atropine


Glycopyrrolate

What are the routes of administration for atropine and glycopyrrolate?

IV


IM


SC


IT

Atropine characteristics

Faster onset


Shorter peak


Shorter duration

Glycopyrrolate

Slower onset


Longer peak


Longer duration

What are the anticholinergic effects on the CNS

Limited effect

What are the anticholinergic effects on the cardiovascular system

Prevent bradycardia

What are the anticholinergic effects on the secretions of the body

Decreases

What are the anticholinergic effects on the eye

Mydriasis (dilation)


Corneal drying

What are the anticholinergic effects on the lungs

Bronchodilation

What are some adverse anticholinergic effects?

Cardiac arrhythmia


Thickened respiratory and salivary excretions


Intestinal peristalsis inhibition

What is an adverse effect of atropine?

Temporary bradycardia

What are four classes of tranquilizers and sedatives?

Phenothiazines


Benzodiazepines


Alpha2-adrenoceptor agonists


Alpha2-antagonists

What is an example of a phenothiazine?

Acepromazine

Acepromazine characteristics

Prenanesthetic sedation


Decreases the dose of general anesthetics


Eases induction and recovery


Can be used with opioids for minor procedures


No reversal agent


Metabolized by the liver


Will slowly cross the placenta

For which species of animals is acepromazine approved?

Horses


Cats


Dogs

What is the route of administration for acepromazine?

IV


IM

What are the effects of acepromazine on the CNS

Calming


Reluctance to move


Decreased interest in surroundings

Are cats as sedated as horses or dogs with acepromazine?

No

Is acepromazine an analgesic?

No

What are the effects of acepromazine on the cardiovascular system?

Hypotension


Increased heart rate


Hypothermia


Protects against arrhythmias


Decreases cardiac output

What are the effects of acepromazine on the respiration system?

Worsens respiratory depression effect of other drugs

What are the effects of acepromazine on the gastrointestinal system?

It is an antiemetic

Does acepromazine prevent histamine release and decrease allergic responses?

Yes