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152 Cards in this Set

  • Front
  • Back
What is the definition of anesthesia?
Loss of sensation
What is general anesthesia?
Loss of consciousness and loss of sensation
True/false: Local anesthesia provides analgesia and anesthesia to a limited area
True
Name two dissociative anesthetics
Ketamine
Teletamine
What general drug classes provide analgesia?
Opioids
Dissociative anesthetics
Alpha 2 agonists
True/false: With neuroleptanalgesia, an animal may seem unconscious but with stimulation will become aware.
True
When should you optimally do a pre-anesthetic evaluation?
1-7 days prior to anesthesia; often is done the same day though
Is there such a thing as safe anesthesia?
NO, only safe ANESTHETISTS
What is the minimal amount of time you should fast an animal pre-op? What is the optimal amount of time?
6 hrs
8-12 hrs preferred
Why might you not fast a young or very small patient prior to surgery?
Due to hypoglycemia
Why shouldn't you give regularly administered meds between pre-med and induction?
Because it can be retained in esophagus or pharynx
Which of the following can cause additive effects when mixed with anesthetics: Aminoglycosides, Barbiturates, Corticosteroids, Digitalis.
Barbiturates
Which causes an increased depressant effect of anesthesia which is severe, aminoglycosides or B-adrenergic agonists (propranolol)?
B-adrenergic agonists
Which may impair ventilation and have renal concerns when mixed with anesthesia, aminoglycosides or Ca channel blockers?
Aminoglycosides
H2 blockers and NSAIDS are enzyme inducers or enzyme inhibitors?
Enzyme inhibitors, which means they prolong the activity of other drugs
Barbiturates and benzodiazepines are enzyme inducers or enzyme inhibitors?
Enzyme inducers
What is the minimum data base of bloodwork performed pre-op?
PCV, TP, BUN
What is normal PCV?
>27-30
True/false: Pre-op bloodwork varies with patient (based on age, presentation and dz process).
TRUE
Subtle changes in renal and hepatic function are normal, but if > ___x, you should investivate.
2
What effect does increased potassium have on the heart?
Bradycardia and arrest
What effect does decreased potassium have on the heart?
Irritated myocardium
You are presented with a normal, healthy dog for OHE who has no systemic diseases. What ASA classification is this?
ASA 1
You are presented with a dog who was HBC. What ASA classification is this?
ASA 5
Which ASA classification covers mild systemic disease (obesity, simple fracture, compensated heart dz)?
ASA 2
Which ASA classification covers severe systemic disease that is under control (hepatic/renal)?
ASA 3
Which ASA classification covers severe systemic dz that is not under control and is a threat to life (shock, hepatic/renal, fever)?
ASA 4
What designation can be added to ASA classifications to denoted that it is an emergency?
E
How should you dose an obese patient who is >25% over normal body weight?
Dose based on lean BW - remember, obese animal has brain of normal weight!
Do you need to use the anesthesia machine with chemical restraint?
No, in fact, lack of an anesthesia machine is a reson for doing chemical restraint
What are some disadvantages of using chemical restraint?
All-or-nothing
Prolonged recovery
No airway control
Monitoring overlooked
Describe good induction:
Quiet, quick
Rapid control of airways
What is the most common way to induce anesthesia?
IV (either bolus or titration)
When might you use IM anesthetic induction?
Wild animal
Fractious animal
On what animal might you use a nasotracheal tube?
Foal under sedation
What are some disadvantages of using chemical restraint?
All-or-nothing
Prolonged recovery
No airway control
Monitoring overlooked
Describe good induction:
Quiet, quick
Rapid control of airways
What is the most common way to induce anesthesia?
IV (either bolus or titration)
When might you use IM anesthetic induction?
Wild animal
Fractious animal
On what animal might you use a nasotracheal tube?
Foal under sedation
When should you intubate?
When anesthetic depth is 2/3 of stage 3
Regular breathing
Normal pupil size
Relaxed 3rd eyelid
Rotated eyeball
Decreased palpebral reflex
Decreased laryngeal reflex
Which reflex goes first, the lateral or medial palpebral?
Lateral
What is the most reliable way to insure that the ET tube is in the trachea?
Visualize tube between arytenoids
After induction, what is one of the most important things to check?
Palpate pulse
What are some common complications associated with induction?
Apnea
Excitement
Hypoxemia
Regurgitation
Laryngospams
What are the three phases of recovery?
Emergence
Early recovery
Late recovery
Which stage of recovery is characterized as the period between discontinuation of anesthesia and extubation?
Emergence
Which stage of recovery is characterized by an ambulatory animal that is still under the influence of sedatives?
Early recovery
What stage of recovery = FULL recovery?
Late recovery
Describe a good recovery.
Quiet, fast control of airway
Appropriate analgesia
If you give an epidural, what do you have to remember during recovery?
Express the animal's bladder
Why should you disconnect the patient before moving?
Prevent tracheal tear
When should you extubate?
Mouth and nose clean
Regular breathing
Well oxygenated
Swallowing reflex
How do you handle extubation in brachycephalics?
Leave tube in until they reject it
Where should you be positioned to extubate an animal?
Behind it
What is the most important monitoring tool on/in the patient?
Esophageal stethescope
Why is an esophageal stethescope important?
Tells HR and rhythm
Whether it is ALIVE or NOT
What does an ECG reflect?
Electrical activity of the heart
What should you use for arrhythmia diagnosis?
ECG
Does ECG provide indication of CO?
NO
What lead should you focus on when doing an ECG?
Lead II
What is the equation for MAP?
MAP = CO x SVR
Systolic pressure should be:
90-100 mmHg
MAP should be:
70-90 mmHg
What are the two indirect methods of measuring indirect arterial BP?
Doppler flow
Oscillometer
Which provides you with more information, Doppler flow or Oscillometer?
Oscillometer, not only does systolic BP, but also does HR, diastolic and MAP
You should use indirect arterial BP measurements (doppler and oscillimeter) on larger or small patients?
Small patients
Which provides a measure of systolic BP only, Doppler or Oscillimeter?
Doppler
Which one gives automatic trends of BP and is easier to use, Doppler or Oscillimeter?
Oscillimeter
What is the gold standard for arterial BP measurement?
Direct BP (IV cath in peripheral artery)
True/false: Direct BP measurement only gives systolic BP information.
False, gives continuous information on systolic, diastolic and MAP
How can you measure how the heart handles venous return?
Central venous pressure (cath in right jugular that measures luminal pressure of cranial vena cava or right atrium)
Name some things that can interfere with the Pulse-Ox.
Hair
Pigmentation
Vasoconstriction
Decreased perfusion
Motion
Which produces a waveform, capnograph or capnometer?
Capnograph
What is the optimal end tidal CO2 measurement provided by either a capnograph or capnometry?
35-45 mmHg
CO2 increases or decreases with expiration?
Increases
What is the gold standard for ventilatory status determination?
Arterial blood gas
How can you monitor renal physiology?
Urine production - 1-2 mL/kg/hr
True/false: General anesthesia includes unconsciousness, analgesia, muscle relaxation and absence of reflex responses.
TRUE
What stage of anesthesia does this describe: Voluntary movement, awake/asleep/sedated, includes the initial admin of induction agent to unconsciousness.
Stage 1
During which stage of anesthesia might you have voluntary motor activity, cough, laryngeal reflexes, salivation and vomition?
Stage 1
During which stage of anesthesia is there delirium with involuntary movement, loss of consciousness, exaggerated reflexes and jaw tone?
Stage 2
Surgical anesthesia is achieved in which anesthetic stage?
Stage 3
Eyeball movement, unconscious, reduced muscle tone, normal HR and RR, loss of laryngeal response but intact palpebral reflexes. The above describe what plane of stage 3 anesthesia?
Light
Describe the medium plane of stage 3 anesthesia.
Stable pulse and RR
Palpebral reflexes sluggish
Eye partially obscured by 3rd eyelid
Adequate for most surgical procedures
Decreased intercostal muscle function, decreased Vt, increased RR, a centered and dilated pupil with no palpebral reflex describes what stage of anesthesia?
Deep plane, stage 3
What stage of anesthesia causes extreme CNS depression, a barely detectable BP, shock and widely dilated pupils that don't respond to light?
Stage 4 - WE DON'T WANT THIS
What cranial nerves are related to the palpebral reflexes?
5 and 7
What cranial nerves are related to PLR?
2 and 3
True/false: Ear flicks in cats are reliable signs of anesthetic depth.
False
True/false: HR, RR, BP and mm color are the most reliable signs of anesthetic depth.
False
True/false: PLR, eyeball position and palpebral reflexes are unreliable signs of anesthetic depth.
False
What is metabolic scaling?
Decreased metabolic rate per kg in larger animals (so mouse requires more anesthetic per kg than does an elephant)
True/false: Pre-medications help decrease anesthetic requirements, decrease qirway secretions and help suppress/induce vomiting.
TRUE
What two pre-med drugs are considered anticholinergics?
Atropine
Glycopyrrolate
Which crosses the BBB, atropine or glycopyrrolate?
Atropine
Which is a competative antagonist of Ach at muscarinic receptors, atropine, diazepam, or ace?
Atropine (anticholinergic)
True/false: anticholinergics are reversible
TRUE
What is atropine's affect on HR?
Increases it
Do anticholinergics provide analgesia?
NO
What are the general effects of atropine?
Decrease SLUD
Increase HR
Bronchodilation
Mydriasis
What is mydriasis?
Pupil dilation
What are the four uses of acepromazine?
Excellent sedative
Antiemetic
Antihistamine
Antiarrhythmic
Which drug blocks dopamine receptors in CNS, serotonin and alpha 1 receptors, diazepam, metatomadine or ace?
Ace
Does ace (and other phenothiazines) provide analgesia?
NO
True/false: Ace is synergystic with opiods.
TRUE
Why might atropine cause colic in a horse?
Decreases secretions and causes GI stasis
What two drugs cause relaxation of the retractor penis muscle?
Ace and Xylazine
Why might you not want to use Ace in a hypovolemic animal who has anemia or shock?
Because it causes vasodilation as well as decreases PCV, TP and platelet function
Is Ace reversible or irreversible?
Irreversible
High doses of Ace can cause what?
Hypotension
True/false: The use of Ace will allow you to decrease your MAC.
TRUE
Which causes better sedation, Ace or diazepam?
Ace
Which is an anticonvulsant, Ace or diazepam?
Diazepam
What is the mechanism of action of benzodiazepines?
Bind to GABAa receptors and increase affinity
What is the reversal agent for benzodiazepines?
Flumazenil
Which would be better to use in a patient with heart and respiratory problems, Diazepam or Xylazine?
Diazepam - benzodiazepines have very minimal CV and respiratory effects
True/false: Diazepam may cause paradoxical excitement.
True
Name two benzodiazepines.
Diazepam
Midazolam
Which class of drugs can cause facial edema in horses and emesis in cats?
Alpha-2 agonists
What are the physiologic changes associated with alpha-2 agonists?
Decreased CO, RR, Vt, HR
Sedation
Analgesia
Muscle relaxation
Put the alpha-2 agonists in order of increases alpha-2 affinity.
Xylazine
Romifidine
Meditomadine
Dexmeditomadine
Who is more sensitive to xylazine, a cow or a dog?
Cow
Who is more sensitive to xylazine, a horse or a pig?
Horse
True/false: With xylazine, there is arousal with auditory stimuli.
True
Which has more predictable sedation and analgesia, medetomidine or xylazine?
Medetomidine
Which has to be used off-label in cats, medetomidine or dexmedetomidine?
Medetomidine
Is romifidine approved for large or small animals?
Large only
Detomidine is used in which animals?
Horses and cows
What are some contraindications for use of alpha-2 agonists?
Arrhythmias, hypotension, shock, urinary tract obstruction
What is the reversal agent for Medetomidine and Dexmeditomidine?
Antipemazole
Which is more selective for alpha-2, antipemazole or yohimbine?
antipemazole
What are the full agonist opioids?
Morphine, oxymorphone, hydromorphone, fentanyl
What is the partial agonist opioid?
Buprenorphine
What is the agonist-antagonist opioid?
Butorphenol
Opioids cause presynaptic inhibition of which receptors?
Ach, Dopa, NE, Substance P
What is the full antagonist opioid?
Naloxone
True/false: You can see excitation/dysphoria with high doses of opioids.
True
True/false: Opioids can cause nausea and vomiting.
True
naproxen
Analgesics
Drug Class: NSAID
Brand: Naprosyn
Use: anti-inflammatory, analgesic
Which can cause histamine release, morphine, oxymorphone, or hydromorphone?
Morphine
Which causes less vomiting, morphine or oxy/hydromorphone?
Oxy/hydromorphone
True/false: Both morphine and fentanyl provide excellent analgesia.
True
Which of the opioids has the most rapid onset and shortest duration?
Fentanyl
Does Fentanyl cause a histamine release?
NO
Which two opioids cause less respiratory depression?
Buprenorphine
Butorphanol
Which allows for better sedation, buprenorphine or butorphanol?
Butorphanol
Why is Butorphanol highly used in equine patients?
Because there are less GI side effects
True/false: Naloxone shoud be given slowly IM or IV and reverses everything, including analgesia.
True
Which drug that we talked about lowers the seizure threshold and can cause hypotension?
Ace
You have an animal present to you that was HBC and is shocky. You want to give him Ace as a pre-med. Should you?
No - It decreases PCV, TP and platelet function and it causes hypotension, so definitely shouldn't use it in an already hypotensive shocky animal.
What does the ASA classification system help us with?
Determining patient risk factors for anesthesia (there are of course other risk factors to take into consideration)