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14 Cards in this Set
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- Back
Phenylephrine
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Dose:100 mcg/ bolus, or 20 mg/250 ml gtt =8 mcg/ml
Use:AntiHYPOtensive Mechanism: Alpha 1 agonist Effects:Vasoconstriction, Increased coronary blood flow, Reflex bradycardia, Elimination:Hepatic Duration: 5+ min |
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Epinephrine
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DOSE:0.01-0.1 mg bolus or 0.1-0.2 mcg/kg/min
USE:AntiHYPOtesive MECHANISM: Alpha 1, Beta 1, Beta 2 agonists EFFECT: increase HR, Contractility, Coronary perfustion pressure, bronchodilation, Decrease renal arterial flow, Decrease splanchnic arterial flow. ELIMINATION: Enzymatic DURATION:~3 min |
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Ephedrine
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DOSE:5-10 mg (0.1 mg/kg)
USE:antiHYPOtensive MECHANISM:catecholamine agonist EFFECT: Increase Heart rate, Cardiac output and Blood Pressure, ANTIEMETIC post spinal, vasopressor ELIMINATION: some liver metabolism, Renal elimination DURATION: 5-10 min effect, Beta1/2 = 3-6 hours |
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Levophed
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DOSE:0.4-.4 mcg/kg/min (mix 4 mg in 250 cc)
USE:AntiHYPOtesive MECHANISM: Alpha 1, Beta 1,Beta 2, Vasoconstriction EFFECT: increase SVR, increase contractility, Reflex bradycardia, thachyarrythmias, HTN, Headache, Decrease cardiac output. ELIMINATION: DURATION: Short acting |
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Dopamine
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DOSE: (effect dependent)
2-10 mcg/kg/min = Beta 1 agonist, 10+ mcg/kg/min= Alpha 1 agonist USE:AntiHYPOtesive MECHANISM: (dose dependent)( 2mcg/kg/min beta 1 agonist): = contractility, increased SA rate and enhanced impulse conduction in the heart. (10+ mcg/kg/min ) Vasoconstriction, potentially angerously so. (Dopamine is a Norepi precursor) EFFECT: (10+) Increase renal output, Vasoconstriction, tachycardia, Headache, Hypertension ELIMINATION: urine B 1/2 ~12 hours DURATION: 10 minutes |
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Dobutamine
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DOSE:2-20 mcg/kg/min
USE:inotropic support of heart MECHANISM: EFFECT: increase stroke volume without increasing heart rate. ELIMINATION: Hepatic catechol metabolism, renal elimination DURATION: 2 minutes |
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Clonadine
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Dose: 3-5 mg
Use: antiHYPERtensive Mechanism: Alpha 2 Agonist, sympatholytic Effects:decrease SVR, Brady cardia, Respiratory depression, Rebound hypertension, Elimination: Hepatic and renal Duration:~12 hours |
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Fenoldopam
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DOSE:0.1-.16 mcg/kg/min
USE:AntiHYPERtesive MECHANISM: Dopaminergic 1 receptors on heart and Alpha 2 agonist EFFECT: Increase renal blood flow, decrease PVR ELIMINATION: conjugation, then renal excretion DURATION: 30 minutes |
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Labetolol
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Dose 0.1-0.25 mg/kg
Purpose: AntiHYPERtensive Mechanism: Alpha and Beta blocker (1:7 ratio) |
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Metoprolol
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Dose: 2mg then 1 mg.
Purpose: AntiHYPERtensive Precautions: don't give if HR < 70 |
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Esmolol
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Dose: 0.2-0.5 mg/kg
Purpose: AntiHYPERtensive Action: B1 blocker Effect decreases HR. |
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Nitro
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Dose: 50 mcg
Purpose: AntiHYPERtensive (5 ml in 20 me= 50 mcg/ml) |
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Hydralazine
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Dose 20-50 mg IV bolus
Purpose: AntiHYPERtensive Mechanism: Alpha 1 antagonist: Give if low HR, |
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Cardene
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Dyhydropyridine
Dose 200-250 mcg (25 mg vial in 250 ml) Purpose: AntiHYPERtensive |