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17 Cards in this Set
- Front
- Back
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negative rewards are aversive such as increased anxiety and dysphoria by what pathway
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GABA
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reinforcement is in what 2 brain areas
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ventral tegmental area and nucleus accumbens
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what is early partial remission
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one or more criteria for substance dependence for at least one month but less than 12 months
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what is sustained partial remission
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one or more criteria but not full criteria have been met for substance dependence for 12 months or longer
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Early partial remission
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no criteria met for abuse or dependence for at least one month but less than six months
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Sustained full remission
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no criteria met for abuse or dependence for 12 months or longer
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what labs suggest ETOH dependence
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BAL >100 exam- >300 anytime
MCV, GGT, AST, ALT, PT, Amylase, lipids, uric acid, all high low- WBC, K, NA |
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polytherapy is a newer approach that matches drugs required for safe and effective withdrawal with neurotransmitter deficits created by substance use which are 5 types of meds
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SSRI
Opioid antagonists (Revex, Vivitrol, or Revia) NMDA agonists anitseizure- tegretol or depakote andrenergic meds- to decrease bloodpressure and pulse associated with high withdrawal |
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what are 4 anticraving medications
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Revia, Campral, Zofran, Buprenex
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Antabuse or Disulfiram
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DO NOT administer until ETOH free for at least 12 hours
Advise client to refrain from ETOH or anything that contains ETOH... vinegar, aftershave, perfumes, mouthwash, cough meds for 2 weeks after stopping med) can increase LFTs can induce mania AVERSION TX if ETOH ingested causes headache, nausea, flushing, vomiting |
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what SSRI is given to treat ETOH craving and why
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Celexa- reduce liking of ETOH
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Buprenex
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decreased heroin craving and use of opiates
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Revex
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blocks ETOH induced release of dopamine
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REvia or Vivitrol
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blocks opioid receptors in rewarding effects of ETOH
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Campral
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increases abstinence through decreased ETOH craving and alter tolerance
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Zofran
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Selective inhibitor of Serotonin 5HT3, increases abstinence, decreases craving
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review diagnostics for abuse vs. dependence
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in bookkkkk
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